Analgesic safety and efficacy of diclofenac sodium softgels on postoperative third molar extraction pain

Journal of Oral and Maxillofacial Surgery

Volumn 62, Issue 7, 2004, Pages 806-815

  Zuniga, John R ^a,d   Phillips, Ceib L ^a   Shugars, Daniel ^a   Lyon, James A ^b   Peroutka, Stephen J ^b,c   Swarbrick, James ^b   Bon, Charles ^b  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b AAIPharma Inc   (United States)

^c Synergia Pharma Inc   (United States)

^d UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DICLOFENAC; DICLOFENAC POTASSIUM; PLACEBO;

ADULT; ANALGESIA; ANALGESIC ACTIVITY; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG FORMULATION; DRUG SAFETY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MOLAR TOOTH; NAUSEA; PAIN ASSESSMENT; POSTOPERATIVE PAIN; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; SIDE EFFECT; SINGLE BLIND PROCEDURE; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; SYNCOPE; TOOTH DISEASE; TOOTH EXTRACTION; TREATMENT OUTCOME; VOMITING;

ADOLESCENT; ADULT; ANALGESICS, NON-NARCOTIC; ANALYSIS OF VARIANCE; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CAPSULES; DICLOFENAC; FEMALE; HUMANS; MALE; MOLAR, THIRD; PAIN MEASUREMENT; PAIN, POSTOPERATIVE; PATIENT SATISFACTION; PLACEBOS; SINGLE-BLIND METHOD; TIME FACTORS; TOOTH EXTRACTION; TOOTH, IMPACTED; TREATMENT OUTCOME;

EID: 3042811401     PISSN: 02782391     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joms.2003.12.019     Document Type: Article

References (18)

1. Conrad S.M., Blakey G.H., Shugars D.A., et al. Patient's perception of recovery after third molar surgery. J Oral Maxillofac Surg. 57:1999;1288
2. Cooper S.A. Models for clinical assessment of oral analgesics. Am J Med. 11:1983;24
3. Cooper S.A., Beaver W.T. A model to evaluate mild analgesics in oral surgery outpatients. Clin Pharmacol Ther. 20:1976;241
4. Menasse R., Hedwall P.R., Kraetz C., et al. Pharmacological properties of diclofenac sodium and its metabolites. Scand J Rheumatol Suppl. 22:1978;5
5. Ku E.C., Lee W., Kothari H.V., et al. The effects of diclofenac sodium on the arachidonic cascade. Semin Arthritis Rheumat. 15:1985;36
6. John V.A. The pharmacokinetics and metabolism of diclofenac sodium (Voltarol®) in animals and man. Rheumatol Rehab. 2:1979;22
7. Todd P.A., Sorkin E.M. Diclofenac sodium a reappraisal of its pharmacodynamic and pharmocokinetic properties, and therapeutic efficacy. Drugs. 35:1988;244
8. Shiba R., Morishita M., Takada K., et al. Clinical evaluation of a new anti-phlogistic and analgesic agent Comparative study between sodium-O-(2, 6-dichloroanilino) phenylacetate (GP 45840) and indomethacin by double-blind method. Prospect Dental Field. 40:1972;334
9. Hultin M., Olander K.J. A clinical trial of the analgesic properties of Voltaren (diclofenac sodium). Scand J Rheumatol. 22:1978;42
10. Nuutinen L.S., Wuolijoki E., Pentikainen I.T. Diclofenac and oxycodone in treatment of postoperative pain A double-blind trial. Acta Anaesth Scand. 30:1986;620
11. Lundstram S., Ivarsson L., Lindglad L., et al. Treatment of biliary pain by prostaglandin synthetase inhibition with diclofenac sodium. Curr Ther Res. 37:1985;435
12. Frame J.W., Rout P.G.J. A comparison of the analgesic efficacy of flurbiprofen, diclofenac, dihydrocodeine/paracetamol and placebo following oral surgery. Br J Clin Pract. 40:1986;463
13. Hersh E.V., Levin L.M., Cooper S.A., et al. Conventional and extended-release etodolac for postsurgical dental pain. Clin Ther. 21:1999;1333
14. Hersh E.V., Cooper S.A., Levin L.M., et al. A dose-ranging study of bromfenac sodium in oral surgery pain. Oral Surg. 86:1998;36
15. Cooper S.A., Reynolds D.C., Reynolds R.N., et al. Analgesic efficacy and safety of (R)-ketoprofen in postoperative dental pain. J Clin Pharmacol. 38:1998;11S
16. Winter L., Bass E., Recant B., et al. Analgesic activity of ibuprofen (Motrin) in postoperative and surgical pain. Oral Surg. 45:1978;159
17. Lundstam S., Wahlander L., Kral J.G. Treatment of ureteral colic by prostaglandin synthetase inhibition with diclofenac sodium. Curr Ther Res. 28:1980;355
18. Willkens R.F. Worldwide clinical safety experience with diclofenac. Sem Arthitis Rheumat. 15:(suppl 1):1985;105