Purification and characterization of pheromaxein, the porcine steroid-binding protein: A member of the secretoglobin superfamily

European Journal of Biochemistry

Volumn 271, Issue 13, 2004, Pages 2593-2606

  Austin, Corrine J ^a   Emberson, Louise ^b   Nicholls, Peter ^b  

^a UNILEVER RESEARCH   (United Kingdom)

^b UNIVERSITY OF KENT   (United Kingdom)

Author keywords

Androstenone; Lipocalin; Pheromaxein; Secretoglobin; Steroid binding protein

Indexed keywords

PEPTIDE; PHEROMAXEIN A; PHEROMAXEIN C; PHEROMONE DERIVATIVE; PORCINE STEROID BINDING PROTEIN; PROSTATEIN; PROTEOLIPID PROTEIN; STEROID BINDING PROTEIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; MATING; MOLECULAR WEIGHT; MULTIGENE FAMILY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROSTATE; PROTEIN ANALYSIS; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PROTEIN PURIFICATION; PROTEIN SECRETION; SEQUENCE HOMOLOGY; SUBMANDIBULAR GLAND; TRANSCRIPTION INITIATION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CARRIER PROTEINS; CLONING, MOLECULAR; DNA, COMPLEMENTARY; MALE; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID; SEQUENCE HOMOLOGY, NUCLEIC ACID; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SUBMANDIBULAR GLAND; SWINE;

ANIMALIA; MAMMALIA; SUIDAE;

EID: 3042810290     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.2004.04188.x     Document Type: Article

References (35)

1. Babol, J., Squires, E.J. & Bonneau, M. (1996) Factors regulating the concentrations of 16-androstene steroids in submaxillary glands of pigs. J. Anim. Sci. 74, 413-419.
2. Booth, W.D. (1984) Sexual dimorphism involving steroidal pheromones and their binding protein in the submaxillary salivary gland of the Gottingen minature pig. J. Endocrinol. 100, 195-202.
3. Booth, W.D. & White, C.A. (1988) The isolation, purification and some properties of pheromaxein, the pheromonal steroid binding protein, in porcine submaxillary glands and saliva. J. Endocrinol. 118, 47-57.
4. Booth, W.D. (1987) Factors affecting the pheromone composition of voided boar saliva. J. Reprod. Fertil. 81, 427-431.
5. Marchese, S., Pes, D., Scaloni, A., Carbone, V. & Pelosi, P. (1998) Lipocalins of boar salivary glands binding odours and pheromones. Eur. J. Biochem. 252, 563-568.
6. Loebel, D., Scaloni, A., Paolini, S., Fini, C., Ferrara, L., Breer, H. & Pelosi, P. (2000) Cloning, post-translational modifications, heterologous expression and ligand binding of boar salivary lipocalin. J. Biochem. (Tokyo) 350, 369-379.
7. Singer, A.G. & Macrides, F. (1992) Lipocalins associated with mammalian pheromones. In Chemical Signals in Vertebrates (Doty, R.L. & Muller-Schwarze, D., eds), p. 365. Plenum Press, New York.
8. Schenkels, L.C.P.M., Veerman, E.C.I. & Amerongen, A.V. (1995) EP-GP and the lipocalin VEGh, two different human salivary 20 kDa proteins. J. Dent. Res. 74, 1543.
9. Krishnan, R.S. & Daniel, J.C. (1967) Blastokinin: inducer and regulator of blastocyst development in the rabbit uterus. Science 158, 490-492.
10. Peeters, B., Rombauts, W., Mous, J. & Heyns, W. (1981) Structural studies on rat prostatic binding protein. The primary structure of its glycosylated component C3. Eur. J. Biochem. 115, 115-121.
11. Peeters, B., Heyns, W., Mous, J. & Rombauts, W. (1982) Structural studies on rat prostatic binding-protein: the primary structure of component C1 from subunit-F. Eur. J. Biochem. 123, 55-62.
12. Peeters, B., Heynes, W., Mous, J. & Rombauts, W. (1983) Structural studies on rat prostatic binding protein. The primary structure of component C2 from subunit S. Eur. J. Biochem. 132, 669-679.
13. Baker, M.E. (1983) Amino acid sequence homology between rat prostatic binding protein and rabbit uleroglobin. Biochem. Biophys. Res. Commun. 114, 325-330.
14. Zhao, C.Q., Nguyen, T., Yusifov, T., Glasgow, B.J. & Lehrer, R.I. (1999) Lipophilins: human peptides homologous to rat prostatein. Biochem. Biophys. Res. Commun. 256, 147-155.
15. Watson, M.A. & Fleming, T.P. (1996) Mammaglobulin, a mammary specific member of the uleroglobin gene family, is overexpressed in human breast cancer. Cancer Res. 56, 860-865.
16. Colpills, T.L., Billing-Medel, P., Friedman, P., Granados, E.N., Hayden, M., Hodges, S., Menhart, N., Roberts, L., Russell, J. & Stroupe, S.D. (2001) Mammaglobin is found in breast tissue as a complex with BU101. Biochemistry 40, 11048-11059.
17. Dominguez, P. (1995) Cloning of a Syrian-hamster cDNA related to sexual dimorphism: establishment of a new family of proteins. FEBS Lett. 376, 257-261.
18. Alvarez, J., Vinas, J., Martin Alonso, J.M., Pablo Albar, J., Ashman, K. & Dominguez, P. (2002) Characterization and cloning of two isoforms of heteroglobin, a novel heterodimeric glycoprotein of the secretoglobin- uteroglobin family showing tissue-specific and sex differential expression. J. Biol. Chem. 277, 233-242.
19. Sambrook, J., Fritsch, E.F. & Maniatis, T. (1989) Molecular Cloning: a Laboratory Manual, 2nd edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
20. Folch, J. (1957) A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem. 226, 498-509.
21. Hellman, U., Werstedt, C., Gonez, J. & Heldin, C.-H. (1995) Improvement of an in-gel digestion procedure for the micro-preparation of internal protein-fragments for amino acid sequencing. Anal. Biochem. 224, 451-455.
22. Booth, W.D. & von Glos, K.I. (1991) Pheromaxein, the pheromonal steroid-binding protein, is a major protein synthesised in porcine submaxillary salivary glands. J. Endocrinol. 128, 205-212.
23. Redl, B. (2000) Human tear lipocalin. Biochim. Biophys. Acta 1482, 241.
24. Lehrer, R.I., Xu, G.R., Abduragimov, A., Dinh, N.N., Qu, X.D., Martin, D. & Glasgow, B.J. (1998) Lipophilin, a novel heterodimeric protein of human tears. FEBS Lett. 432, 163-167.
25. Kasper, S. & Matusik, R.J. (2000) Rat probasin: structure and function of an outlier lipocalin. Biochim. Biophys. Acta 1482, 249-258.
26. Lea, O.A., Petrusz, P. & French, F.S. (1979) Prostatein: major secretory protein of the rat ventral prostate. J. Biol. Chem. 254, 6196-6202.
27. Crossett, B., Allen, W.R. & Stewart, F. (1996) A 19 kDa protein secreted by the endometrium of the mare is a novel member of the lipocalin family. Biochem. J. 320, 137-143.
28. Muller-Schottle, F., Classen-Linke, I., Alfer, J., Krusche, C., Beier-Hellwig, K., Sterzik, K. & Beier, H.M. (1999) Expression of uteroglobin in the human endometrium. Mol. Human Reprod. 5, 1155-1161.
29. Bratt, T.B. (2000) Lipocalins and cancer. Biochim. Biophys. Acta 1482, 318-326.
30. Clissold, P.M. & Bishop, J.O. (1982) Variation in mouse major urinary protein genes and the MUP gene: products within and between inbred lines. Gene 18, 211-220.
31. Clarke, A.J., Chave-Cox, A., Ma, X. & Bishop, J.O. (1985) Analysis of mouse urinary protein genes. EMBO J. 4, 3167-3171.
32. Evershed, R.P., Robertson, D.H.L., Beynon, R.J. & Green, B.N. (1993) Application of electrospray ionization mass spectrometry with maximum-entropy analysis to allelic fingerprinting of major urinary proteins. Rapid Commun. Mass Spectrom. 1, 882-886.
33. Robertson, D.H.L., Cox, K.A., Gaskell, S.J., Evershed, R.P. & Beynon, R.J. (1996) Molecular heterogeneity in the major urinary proteins of the house mouse Mus musculus. Biochem. J. 316, 265-272.
34. Peeters, B., Heyns, W. & Rombauts, W. (1983) Assignment of the disulphide bonds in the subunits S and F of rat prostatic binding protein. De Biochimie de Biophysique. 91, B67-B68.
35. Celis, L., Ciaessens, F., Peeters, B., Heyns, W., Verhoeven, G. & Rombauts, W. (1983) Proteins interacting with an androgen-responsive unit in the C3 (1) gene intron. Mol. Cell. Endocrinol. 94, 165-172.