Inhibins and activin A in hypertensive disorders of pregnancy and HELLP-syndrome;Inhibine und aktivin A bei hypertensiven schwangerschaftserkrankungen und HELLP-syndrom

Zentralblatt fur Gynakologie

Volumn 126, Issue 3, 2004, Pages 148-153

  Seufert, Rudolf ^a   Neubert, S ^a   Tanner, B ^a   Schaffrath, M ^b   Pollow, K ^b   Kolbl H ^a  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^b JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Activin A; HELLP Syndrome; Inhibin A; Inhibin B; Preeclampsia

Indexed keywords

ACTIVIN A; INHIBIN A; INHIBIN B;

ARTICLE; CHILDBIRTH; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HELLP SYNDROME; HIGH RISK POPULATION; HUMAN; MAJOR CLINICAL STUDY; MATERNAL HYPERTENSION; PARAMETER; PROTEIN BLOOD LEVEL; RISK ASSESSMENT; RISK FACTOR; SERUM; STATISTICAL ANALYSIS;

ACTIVINS; FEMALE; HELLP SYNDROME; HUMANS; HYPERTENSION; INHIBIN-BETA SUBUNITS; INHIBINS; PRE-ECLAMPSIA; PREGNANCY; PREGNANCY COMPLICATIONS; PREGNANCY COMPLICATIONS, CARDIOVASCULAR;

EID: 3042807904     PISSN: 00444197     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-822592     Document Type: Article

References (30)

1. Aitken DA, Wallace CM, Crossley JA. Dimeric inhibin A as a marker for Down's syndrom in early pregnancy. N Engl J Med 1996; 334: 1231-1236
2. Aquilina J, Barnett A, Thompson O, Harrington K. Second-trimester maternal serum inhibin A concentration as an early marker for pre-eclampsia. Am J Obstet Gynecol 1999; 181: 131-136
3. Brosens JA, Robertson WB, Dixon HG. The role of spiral arteries in the pathogenesis of preeclampsia. In: Wynn R (ed). Obstetrics Gynecology Annual. Appleton, New York 1972
4. Burger HG, Findlay JK, Robertson DM. Inhibin/Activin/Follistatin. In: Adashi EY, Rock JA, Rosenwaks Z (eds). Reproductive Endocrinology, Surgery, and Technology. Lippincott-Raven, Philadelphia, New York 1995; 801-826
5. Cuckle H, Sehmi I, Jones R. Maternal serum inhibin A can predict pre-eclampsia. Br J Obstet Gynaecol 1998; 105: 1101-1103
6. D'Atonia D, Reis FM, Benedetto C, Evans LW, Groome NP, de Krester DM, Wallace WM, Petraglia F. Increased maternal serum activin A but not follistatin levels in pregnant woman with hypertensive disorders. J Endocrinol 2000; 165: 157-162
7. Davey DA, McGillivray I. The classification and definition of the hypertensive disorders of pregnancy. Am J Obstet Gynecol 1988; 158: 892-898
8. Fraser RF, McAsey ME, Coney P. Inhibin A and pro alpha-C are elevated in preeclamptic pregnancy and correlate with human chorionic gonadotropin. Am J Reprod Immunol 1998; 40: 37-42
9. Groome NP, Illingworth PJ, O'Brien M, Cooke I, Ganesan TS, Baird DT, McNeilly AS. Detection of dimeric inhibin throughout the human menstrual cycle. Clin Endocrinol 1994; 40: 717-723
10. Groome NP, Illingworth PJ, O'Brien M, Priddle J, Weaver K, McNeilly AS. Quantification of inhibin pro alpha-C containing forms in human serum by a new ultrasensitive two-site enzyme-linked immonosorbent assay. J Clin Endocrinol Metab 1995; 80: 2926-2932
11. Groome NP, Illingworth PJ, O'Brien M, Pai R, Rodger FE, Mather JP, McNeilly AS. Measurement of dimeric inhibin B throughout the human menstrual cycle. J Clin Endocrinol Metab 1996; 81: 1401-1405
12. Healy DL, Polson D, Yohkochiya T, de Kretser DM. Inhibin and related peptides in pregnancy. Baillieres Clin Endocrinol Metab 1990; 4: 233-247
13. Illingworth PJ, Groome NP, Duncan WC, Grant V, Tovanabutra S, Baird DT, McNeilly AS. Measurement of circulating inhibin forms during establishment of pregnancy. J Clin Endocrinol Metabol 1996; 81: 1471-1475
14. Knight PG, Muttukrishna S, Groome HP. Development and application of a two-site enzyme immunoassay for the determination of 'total' activin-A concentrations in serum and follicular fluid. J Endocrinol 1996; 148: 267-279
15. McLachlan RI, Healy DL, Lutjen PJ, Findlay JK, deKretser DM, Burger HG. The maternal ovary is not the source of circulating inhibin levels during human pregnancy. Clin Endocrinol 1987; 27: 663-668
16. Messague J. The transforming growth factor beta family. Ann Rev Cell Biol 1990; 6: 667-673
17. Muttukrishna S, George L, Fowler PA, Groome NP, Knight PG. Measurement of serum concentrations of inhibin-A (alpha-beta A dimer) during human pregnancy. Clin Endocrinol 1995; 42: 391-397
18. Muttukrishna S, Fowler PA, George L, Groome NP, Knight PG. Changes in peripheral serum levels of total activin A during the human menstrual cycle and pregnancy. J Clin Endocrinol Metab 1996; 81: 3328-3334
19. Muttukrishna S, Knight PG, Groome NP, Redman CWG, Ledger WL. Activin A and inhibin A as possible endocrine markers for pre-eclampsia. Lancet 1997; 349: 1285-1288
20. Muttukrishna S, North RA, Morris J, Schellenberg JC, Taylor RS, Asselin J, Ledger W, Groom N, Redman CWG. Serum inhibin A and activin A are elevated prior to the onset of pre-eclamsia. Human Reproduction 2000; 15: 1640-1645
21. Muttukrishna S, Fowler PA, Groome NP, Mitchell GG, Robertson WR, Knight PG. Serum concentrations of dimeric inhibin during the spontaneous human menstrual cycle and after treatment withexogenous gonadotrophin. Hum Reprod 1994; 9: 1634-1642
22. Petraglia F, Aguzzoli L, Gallinelli A, Florio P, Zonca M, Benedetto C, Woodruff K. Hypertension in pregnancy: changes in activin A maternal serum concentration. Placenta 1995; 16: 447-454
23. Petraglia F, Luisi S, Benedetto C, Zonca M, Florio P, Casarosa E, Volpe A, Bernasconi S, Genazzani AR. Changes of dimeric inhibin B levels in maternal serum throughout healthy gestation and in women with gestational diseases. J Clin Endocrinol Metab 1997; 82: 2991-2995
24. Qu J, Thomas K. Changes in bioactive and immunoactive inhibin levels around human labor. J Clin Endocrinol Metab 1992; 74: 1290-1295
25. Qu J, Thomas K. Inhibin and activin production in the human placenta. Endocr Rev 1995; 16: 485-507
26. Robertson WB, Brosens J, Dixon HG. Maternal uterine vascular lesion in the hypertensive complications of pregnancy. In: Lindheimer MD, Katz AJ, Zuspan FP (eds). Hypertension in Pregnancy. Wiley, New York 1976
27. Sebire NJ, Roberts L, Noble P, Wallace E, Nicolaides KH. Raised maternal serum inhibin A concentration at 10 to 14 weeks of gestation is associated with pre-eclamsia. Br J Obstet Gynecol 2000; 107: 795-797
28. Silver HM, Lambert-Messerlian GM, Star JA, Hogan J, Canick JA. Comparison of maternal serum total activin A and inhibin A in normal, preeclamptic, and nonproteinuric gestationally hypertensive pregnancies. Am J Obstet Gynecol 1999; 180: 1131-1137
29. Vale W, River C, Vaughan J. The role of inhibin and activin. In: Knobil E, Neill JD (eds). The physiology of reproduction. Raven, New York 1994; 1861-1874
30. Weinstein L. Syndrome of hemolysis, elevated liver enzymes and low platelet count: a severe consequence of hypertension in pregnancy. Am J Obstet Gynecol 1982; 142: 159-167