Application of multiple-response optimization to fluoride release from an extended-release matrix tablet

Pharmazeutische Industrie

Volumn 66, Issue 5, 2004, Pages 601-606

  Tillotson, John ^a   Sakr, Adel ^a  

^a UNIVERSITY OF CINCINNATI   (United States)

Author keywords

Extended release tablets; Fluoride; Matrix tablets; Multiple response; Optimization; Response surface methodology

Indexed keywords

CARBOMER; EUDRAGIT; FLUORIDE; HYDROXYPROPYLMETHYLCELLULOSE; MICROCRYSTALLINE CELLULOSE;

ARTICLE; COMPUTER PROGRAM; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY; MATRIX TABLET; STATISTICAL MODEL; TABLET COMPRESSION;

EID: 3042797870     PISSN: 0031711X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Hamed, E., Sakr, A., Application of multiple response optimization technique to extended release formulations design, J. Contr. Rel. 73, 329 (2001)
2. Takahara, J., Takayama, K., Nagai, T., Multiobjective simultaneous optimization technique based on an artificial neural network in sustained release formulations, J. Contr. Rel. 49, 11 (1997)
3. The United States Pharmacopoeia 25, p. 2052. U. S. Pharmacopoeial Convention, Rockville, MD (2002)
4. Margolis, E., Moreno, E., Murphy, B., Effect of Low Levels of Fluoride in Solution on Enamel Demineralization in vitro, Dent. Res. 65, 23 (1986)
5. Vivien-Castioni, N., Baehni, P., Gurny, R. Current status in oral fluoride pharmacokinetics and implication for the prophylaxis against dental caries, Eur. J. Pharm. Biopharm. 45, 101 (1998)
6. Vivien-Castioni, N., Gurny, R., Baehni, P., Salivary fluoride concentrations following application of bioadhesive tablets and mouthrinses, Eur. J. Pharm. Biopharm. 49, 27 (2000)
7. FDA Guidance for Industry: Dissolution Testing of Immediate Release Solid Oral Dosage Forms. Center for Drug Evaluation and Research (1997)