Molecular identification and expression of two non-P450 enzymes, monoamine oxidase a and flavin-containing monooxygenase 2, involved in phase I of xenobiotic biotransformation in the Pacific oyster, Crassostrea gigas

Biochimica et Biophysica Acta - Gene Structure and Expression

Volumn 1679, Issue 1, 2004, Pages 29-36

  Boutet, Isabelle ^a   Tanguy, Arnaud ^b   Moraga, Dario ^b  

^a IFREMER   (France)

^b UNIVERSITÉ DE BRETAGNE OCCIDENTALE   (France)

Author keywords

Crassostrea gigas; FAD; flavin adenine dinucleotide; flavin containing monooxygenase 2; Flavin containing monooxygenase 2; FMO 2; glutathione S transferase; GST; MAO A; messenger RNA; Monoamine oxidase A; monoamine oxidase A; mRNA; NADP

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING); AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; ATRAZINE; COMPLEMENTARY DNA; CYTOCHROME P450; DIURON; GLYPHOSATE; HYDROCARBON; ISOPROTURON; MESSENGER RNA; QUERCETIN; UNSPECIFIC MONOOXYGENASE;

ARTICLE; BIOLOGICAL MONITORING; BIOTRANSFORMATION; CONTROLLED STUDY; ENZYME REGULATION; EXOCRINE GLAND; GENE SEQUENCE; GENETIC CODE; NONHUMAN; NUCLEOTIDE SEQUENCE; OYSTER; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE SPECIFICITY;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BIOTRANSFORMATION; CLONING, MOLECULAR; DNA, COMPLEMENTARY; MOLECULAR SEQUENCE DATA; MONOAMINE OXIDASE; OSTREIDAE; OXYGENASES; XENOBIOTICS;

BIVALVIA; CRASSOSTREA; CRASSOSTREA GIGAS; GYMNOMYZA SAMOENSIS; OSTREIDAE;

EID: 3042774163     PISSN: 01674781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbaexp.2004.04.001     Document Type: Article

References (40)

1. Boutet I., Tanguy A., Rousseau S., Auffret M., Moraga D. Molecular identification and expression of Heat Shock Cognate (hsc70) and Heat Shock Protein (hsp70) genes in the Pacific oyster Crassostrea gigas. Cell Stress Chaperones. 8:2003;76-85
2. Tanguy A., Mura C., Moraga D. Cloning of a metallothionein gene and characterization of two other cDNA sequences of the Pacific oyster Crassostrea gigas. Aquat. Toxicol. 55:2001;35-47
3. Tanguy A., Moraga D. Cloning and characterization of a gene coding for a novel metallothionein in the Pacific oyster Crassostrea gigas (CgMT2): a case of adaptive response to metal-induced stress? Gene. 273:2001;123-130
4. Tanguy A., Boutet I., Bonhomme F., Boudry P., Moraga D. Polymorphism of metallothionein genes in the Pacific oyster Crassostrea gigas as a biomarker of response to metal exposure. Biomarkers. 7:2002;439-450
5. Boutet I., Tanguy A., Auffret M., Riso R., Moraga D. Immunochemical quantification of metallothioneins in marine mollusks: characterization of a metal exposure bioindicator. Environ. Toxicol. Chem. 21:2002;1009-1014
6. Boutet I., Tanguy A., Moraga D. Response of the Pacific oyster Crassostrea gigas to hydrocarbon contamination under experimental conditions. Gene. 329:2004;147-157
7. Schlenk D. Occurrence of flavin-containing monooxygenases in non-mammalian eukaryotic organisms. Comp. Biochem. Physiol. 121C:1998;185-195
8. Bach A.W., Lan N.C., Johnson D.L., Abell C.W., Bembenek M.E., Kwan S.W., Seeburg P.H., Shih J.C. cDNA cloning of human liver monoamine oxidase A and B: molecular basis of differences in enzymatic properties. Proc. Natl. Acad. Sci. U. S. A. 85:1988;4934-4938
9. Beedham C. The role of non-P450 enzymes in drug oxidation. Pharm. World Sci. 19:1997;255-263
10. Michel X.R., Cassand P.M., Ribera D.G., Narbonne J.F. Metabolism and mutagenic activation of benzo[a]pyrene by subcellular fractions from mussel (Mytilus galloprovincialis) digestive gland and sea bass (Dicenthrarcus labrax) liver. Comp. Biochem. Physiol. 103C:1992;43-51
11. Van der Oost R., Beyer J., Vermeulen N.P.E. Fish bioaccumulation and biomarkers in environmental risk assessment: a review. Environ. Toxicol. Pharmacol. 13:2003;57-149
12. McFadzen I., Eufemia N., Heath C., Epel D., Moore M., Lowe D. Multidrug resistance in the embryos and larvae of the mussel Mytilus edulis. Mar. Environ. Res. 50:2000;319-323
13. Lüdeking A., Köhler A. Identification of six mRNA sequences of genes related to multixenobiotic resistance (MXR) and biotransformation in Mytilus edulis. Mar. Ecol., Prog. Ser. 238:2002;115-124
14. Poulsen L.L., Ziegler D.M. The liver microsomal FAD-containing monooxygenase. Spectral characterization and kinetic studies. J. Biol. Chem. 254:1979;6449-6455
15. Kurelec B. Exclusive activation of aromatic amines in the marine mussel Mytilus edulis by FAD-containing monooxygenase. Biochem. Biophys. Res. Commun. 127:1985;773-778
16. Kurelec B., Krca S. Metabolic activation of 2-aminofluorene, 2-acetylaminofluorene and N-hydroxy-acetylaminofluorene to bacterial mutagens with mussel (Mytilus galloprovincialis) and carp (Cyprinus carpio) subcellular preparations. Comp. Biochem. Physiol. 88C:1987;171-177
17. Schlenk D., Buhler D.R. Xenobiotic biotransformation in the Pacific oyster Crassostrea gigas. Comp. Biochem. Physiol. 94C:1989;476-480
18. Schlenk D., Buhler D.R. The in vitro biotransformation of 2-aminofluorene in the visceral mass of the Pacific oyster, Crassostrea gigas. Xenobiotica. 20:1990;563-572
19. Strolin Benedetti M. Biotransformation of xenobiotics by amine oxidases. Fundam. Clin. Pharmacol. 15:2001;75-84
20. Wouters J. Structural aspects of monoamine oxidase and its reversible inhibition. Curr. Med. Chem. 5:1998;137-162
21. Youdim M.B., Feldman S.C., Pappas G.D., Pollard H.B. Serotonin metabolism and the nature of monoamine oxidase in squid central nervous system. Brain Res. 381:1986;300-304
22. Antipov A.D., Kostkin V.B., Rozengart E.V., Epshtein L.M. A comparative analysis of monoamine oxidase activity in the tissues of the deep-sea squid (Berryteuthis magister) and the mouse under normal and elevated atmospheric pressure. Zh. Evol. Biokhim. Fiziol. 32:1996;233-240
23. Snyder M.J., Girvetz E., Mulder E.P. Induction of marine mollusc stress proteins by chemical or physical stress. Arch. Environ. Contam. Toxicol. 41:2001;22-29
24. Gish W., States D.J. Identification of protein coding regions by database similarity search. Nat. Genet. 3:1993;266-272
25. Myers E.W., Miller W. Optimal alignments in linear space. Comput. Appl. Biosci. 4:1988;11-17
26. Wu H.F., Chen K., Shih J.C. Site-directed mutagenesis of monoamine oxidase A and B: role of cysteines. Mol. Pharmacol. 43:1993;888-893
27. Yueh M.F., Krueger S.K., Williams D.E. Pulmonary flavin-containing monooxygenase (FMO) in rhesus macaque: expression of FMO2 protein, mRNA and analysis of the cDNA. Biochim. Biophys. Acta. 1350:1997;267-271
28. Lawton M.P., Gasser R., Tynes R.E., Hodgson E., Philpot R.M. The flavin-containing monooxygenase enzymes expressed in rabbit liver and lung are products of related but distinctly different genes. J. Biol. Chem. 265:1990;5855-5861
29. Nikbakht K.N., Lawton M.P., Philpot R.M. Guinea pig or rabbit lung flavin-containing monooxygenases with distinct mobilities in SDS-PAGE are allelic variants that differ at only two positions. Pharmacogenetics. 2:1992;207-216
30. Phillips I.R., Dolphin C.T., Clair P., Hadley M.R., Hutt A.J., McCombie R.R., Smith R.L., Shephard E.A. The molecular biology of the flavin-containing monooxygenases of man. Chem.-Biol. Interact. 96:1995;17-32
31. Sabina R.L., Marquetant R., Desai N.M., Kaletha K., Holmes E.W. Cloning and sequence of rat myoadenylate deaminase cDNA. Evidence for tissue-specific and developmental regulation. J. Biol. Chem. 262:1987;12397-12400
32. Shaw G., Kamen R.A. Conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell. 46:1986;659-667
33. Fucci L., Piscopo A., Aniello F., Branno M., Di Gregorio A., Calogero R., Geraci G. Cloning and characterization of a developmentally regulated sea urchin cDNA encoding glutamine synthetase. Gene. 152:1995;205-208
34. Pavé-Preux M., Ferry N., Bouguet J., Hanoune J., Barouki R. Nucleotide sequence and glucocorticoid regulation of the mRNAs for the isoenzymes of rat aspartate aminotransferase. J. Biol. Chem. 263:1988;17459-17466
35. Grimsby J., Lan N.C., Neve R., Chen K., Shih J.C. Tissue distribution of human monoamine oxidase A and B mRNA. J. Neurochem. 55:1990;1166-1169
36. Ziegler D.M. Flavin-containing monooxygenases: catalytic mechanism and substrate specificities. Drug Metab. Rev. 19:1988;1-32
37. Ziegler D.M. Recent studies on structure and function of multisubstrate flavin-containing monooxygenases. Annu. Rev. Pharmacol. Toxicol. 33:1993;179-199
38. Livingstone D.R., Arnold R., Chipman K., Kirchin M.A., Marsh J. The mixed function oxygenase system in molluscs: metabolism, responses to xenobiotics and toxicity. Oceanis. 16:1990;331-347
39. Ramsay R.R. Substrate regulation of monoamine oxidases. J. Neural Transm. 52:1998;139-147
40. Carlo P., Violani E., Del Rio M., Olasmaa M., Santagati S., Maggi A., Picotti G.B. Monoamine oxidase B expression is selectively regulated by dexamethasone in cultured rat astrocytes. Brain Res. 711:1996;175-183