-
1
-
-
0042744723
-
-
For a discussion of antibody plasticity, see: (a) Yin, J.; Beuscher, A. E.; Andryski, S. E.; Stevens, R. C.; Schultz, P. G. J. Mol. Biol. 2003, 330, 651-656.
-
(2003)
J. Mol. Biol.
, vol.330
, pp. 651-656
-
-
Yin, J.1
Beuscher, A.E.2
Andryski, S.E.3
Stevens, R.C.4
Schultz, P.G.5
-
2
-
-
0037011407
-
-
For a review see: (b) Schultz, P. G.; Yin, J.; Lerner, R. A. Angew Chem., Int. Ed. 2002, 41, 4427-4437.
-
(2002)
Angew. Chem., Int. Ed.
, vol.41
, pp. 4427-4437
-
-
Schultz, P.G.1
Yin, J.2
Lerner, R.A.3
-
3
-
-
0030707656
-
-
For examples of protein-protein interface remodeling see: (c) Atwell, S.; Ultsch, M.; DeVos, A. M.; Wells, J. A. Science 1997, 278; 1125-1128
-
(1997)
Science
, vol.278
, pp. 1125-1128
-
-
Atwell, S.1
Ultsch, M.2
DeVos, A.M.3
Wells, J.A.4
-
4
-
-
0033550310
-
-
and (d) Hiipakka, M.; Poikonen, K.; Saksela, K. J. Mol. Biol. 1999, 293, 1097-1106.
-
(1999)
J. Mol. Biol.
, vol.293
, pp. 1097-1106
-
-
Hiipakka, M.1
Poikonen, K.2
Saksela, K.3
-
5
-
-
0031053362
-
-
For examples and reviews, see: (a) Greisman, H. A.; Pabo, C. O. Science 1997, 275, 657-661.
-
(1997)
Science
, vol.275
, pp. 657-661
-
-
Greisman, H.A.1
Pabo, C.O.2
-
6
-
-
0344839044
-
-
(b) Segal, D. J.; Beerli, R. R.; Blancafort, P.; Dreier, B.; Effertz, K.; Huber, A.; Koksch, B.; Lund, C. V.; Magnenat, L.; Valente, D.; Barbas, C. F. Biochemistry 2003, 42, 2137-2148.
-
(2003)
Biochemistry
, vol.42
, pp. 2137-2148
-
-
Segal, D.J.1
Beerli, R.R.2
Blancafort, P.3
Dreier, B.4
Effertz, K.5
Huber, A.6
Koksch, B.7
Lund, C.V.8
Magnenat, L.9
Valente, D.10
Barbas, C.F.11
-
8
-
-
0037711251
-
-
(d) Jamieson, A. C.; Miller, J. C.; Pabo, C. O. Nat. Rev. Drug Discov. 2003, 2, 361-368.
-
(2003)
Nat. Rev. Drug Discov.
, vol.2
, pp. 361-368
-
-
Jamieson, A.C.1
Miller, J.C.2
Pabo, C.O.3
-
9
-
-
0028103855
-
-
For a review, see: (a) Gehring, W. J.; Qian, Y. Q.; Billeter, M.; Furukubotokunaga, K.; Schier, A. F.; Resendezperez, D.; Affolter, M.; Otting, G.; Wuthrich, K. Cell 1994, 78, 211-223.
-
(1994)
Cell
, vol.78
, pp. 211-223
-
-
Gehring, W.J.1
Qian, Y.Q.2
Billeter, M.3
Furukubotokunaga, K.4
Schier, A.F.5
Resendezperez, D.6
Affolter, M.7
Otting, G.8
Wuthrich, K.9
-
11
-
-
0030609996
-
-
TuckerKellogg, L.; Rould, M. A.; Chambers, K. A.; Ades, S. E.; Sauer, R. T.; Pabo, C. O. Structure 1997, 5, 1047-1054.
-
(1997)
Structure
, vol.5
, pp. 1047-1054
-
-
TuckerKellogg, L.1
Rould, M.A.2
Chambers, K.A.3
Ades, S.E.4
Sauer, R.T.5
Pabo, C.O.6
-
14
-
-
3042783729
-
-
note
-
Wild-type engrailed HD binds the palindromic DNA sequence, TAATTA, thereby complicating the interpretation of biochemical experiments. To avoid this difficulty, we chose to work with the Q50K mutant which binds TAATCC.
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-
-
-
15
-
-
0037114031
-
-
and references therein
-
See: He, J. L.; Seela, F. Nucleic Acids Res. 2002, 30, 5485-5496 and references therein.
-
(2002)
Nucleic Acids Res.
, vol.30
, pp. 5485-5496
-
-
He, J.L.1
Seela, F.2
-
16
-
-
3042821415
-
-
See Supporting Information
-
See Supporting Information.
-
-
-
-
19
-
-
0242362269
-
-
For examples of other approaches to engineer small-molecule control over protein-protein and protein-DNA interactions, see: (a) Arndt, H. D.; Hauschild, K. E.; Sullivan, D. P.; Lake, K.; Dervan, P. B.; Ansari, A. Z. J. Am. Chem. Soc. 2003, 125, 13322-13323.
-
(2003)
J. Am. Chem. Soc.
, vol.125
, pp. 13322-13323
-
-
Arndt, H.D.1
Hauschild, K.E.2
Sullivan, D.P.3
Lake, K.4
Dervan, P.B.5
Ansari, A.Z.6
-
20
-
-
0037460166
-
-
(b) Lin, Q.; Barbas, C. F.; Schultz, P. G. J. Am. Chem. Soc. 2003, 125, 612-613.
-
(2003)
J. Am. Chem. Soc.
, vol.125
, pp. 612-613
-
-
Lin, Q.1
Barbas, C.F.2
Schultz, P.G.3
-
21
-
-
0034674624
-
-
(c) Guo, Z. H.; Zhou, D. M.; Schultz, P. G. Science 2000, 288, 2042-2045.
-
(2000)
Science
, vol.288
, pp. 2042-2045
-
-
Guo, Z.H.1
Zhou, D.M.2
Schultz, P.G.3
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