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Volumn 126, Issue 26, 2004, Pages 8078-8079

Adaptability at a protein-DNA interface: Re-engineering the engrailed homeodomain to recognize an unnatural nucleotide

Author keywords

[No Author keywords available]

Indexed keywords

HOMEODOMAIN PROTEIN; NUCLEOTIDE;

EID: 3042770584     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja048113w     Document Type: Article
Times cited : (12)

References (21)
  • 5
    • 0031053362 scopus 로고    scopus 로고
    • For examples and reviews, see: (a) Greisman, H. A.; Pabo, C. O. Science 1997, 275, 657-661.
    • (1997) Science , vol.275 , pp. 657-661
    • Greisman, H.A.1    Pabo, C.O.2
  • 14
    • 3042783729 scopus 로고    scopus 로고
    • note
    • Wild-type engrailed HD binds the palindromic DNA sequence, TAATTA, thereby complicating the interpretation of biochemical experiments. To avoid this difficulty, we chose to work with the Q50K mutant which binds TAATCC.
  • 15
    • 0037114031 scopus 로고    scopus 로고
    • and references therein
    • See: He, J. L.; Seela, F. Nucleic Acids Res. 2002, 30, 5485-5496 and references therein.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 5485-5496
    • He, J.L.1    Seela, F.2
  • 16
    • 3042821415 scopus 로고    scopus 로고
    • See Supporting Information
    • See Supporting Information.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.