Binding specificity of Bacillus thuringiensis Cry1Aa for purified, native Bombyx mori aminopeptidase N and cadherin-like receptors

BMC Biochemistry

Volumn 2, Issue , 2001, Pages 1-8

  Jenkins, Jeremy L ^a,b   Dean, Donald H ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACILLUS THURINGIENSIS TOXIN; BACTERIAL TOXIN; CRY1AA TOXIN; MICROSOMAL AMINOPEPTIDASE; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ARTICLE; BACILLUS THURINGIENSIS; BINDING AFFINITY; BINDING SITE; CORRELATION ANALYSIS; ENZYME PURIFICATION; MEMBRANE VESICLE; MOLECULAR INTERACTION; NONHUMAN; SILKWORM; SURFACE PLASMON RESONANCE;

BACILLUS THURINGIENSIS; BACTERIA (MICROORGANISMS); BOMBYX; BOMBYX MORI; HEXAPODA;

EID: 3042763991     PISSN: 14712091     EISSN: None     Source Type: Journal    
DOI: 10.1186/1471-2091-2-12     Document Type: Article

References (27)

1. Jayaraman K: A caveat: Bt must be allowed, but with caution and after carefully controlled trials. Curr. Sci 1991, 60:465
2. Van Driesche RG, Bellows JTS: Biological Control. New York: Chapman and Hall; 1996
3. Ge AZ, Shivarova NI, Dean DH: Location of the Bombyx mori specificity domain on a Bacillus thuringiensis δ-endotoxin protein. Proc. Natl. Acad. Sci. USA 1989, 86:4037-4041
4. Lee MK, Milne RE, Ge AZ, Dean DH: Location of a Bombyx mori receptor binding region on a Bacillus thuringiensis δ-endotoxin. J. Biol. Chem 1992, 267:3115-3121
5. Lu H, Rajamohan F, Dean DH: Identification of amino acid residues of Bacillus thuringiensis δ-endotoxin Cry1Aa associated with membrane binding and toxicity to Bombyx mori. J. Bacteriol 1994, 176:5554-5559
6. Yaoi K, Kadotani T, Kuwana H, Shinkawa A, Takahashi T, H I, Isato R: Aminopeptidase N from Bombyx mori as a candidate for the receptor of Bacillus thuringiensis Cry1Aa toxin. Eur. J. Biochem 1997, 246:652-657
7. Yaoi K, Nakanishi K, Kadotani T, Imamura M, Koizumi N, Iwahana H, Sato R: cDNA cloning and expression of Bacillus thuringiensis Cry1Aa toxin binding 120 kDa aminopeptidase N from Bomyx mori. Biochim. Biophys. Acta 1999, 1444:131-137
8. Masson L, Lu Y-J, Mazza A, Brousseau R, Adang MJ: The Cry1A(c) receptor purified from Manduca sexta displays multiple specificities. J. Biol. Chem 1995, 270:20309-20315
9. Nakanishi K, Yaoi K, Shimada N, Kadotani T, Sato R: Bacillus thuringiensis insecticidal Cry1Aa toxin binds to a highly conserved region of aminopeptidase N in the host insect leading to its evolutionary success. Biochim. Biophys. Acta 1999, 1432:57-63
10. Shinkawa A, Yaoi K, Kadotani T, Imamura M, Koizumi N, Iwahana H, Sato R: Binding of phylogenetically distant Bacillus thuringiensis Cry toxins to a Bombyx mori aminopeptidase N suggests importance of Cry toxin's conserved structure in receptor binding. Curr. Microbiol 1999, 39:14-20
11. Hua G, Tsukamoto K, Taguchi R, Tomita M, Miyamima S, Ikezawa H: Characterization of aminopeptidase N from the brush border membrane of the larvae midgut of silkworm, Bombyx mori as a zinc enzyme. Biochim. Biophys. Acta 1998, 1383:301-310
12. Hua G, Tsukamoto K, Rasilo M-L, Ikezawa H: Molecular cloning of a GPI-anchored aminopeptidase N from Bombyx mori midgut: a putative receptor from Bacillus thuringiensis Cry1A toxin. Gene 1998, 214:177-185
13. Nagamatsu Y, Toda S, Yamaguchi F, Ogo M, Kogure M, Nakamura M, Shibata Y, Katsumoto T: Identification of Bombyx mori midgut receptor for Bacillus thuringiensis insecticidal Cry1A(a) toxin. Biosci. Biotechnol. Biochem 1998, 62:718-726
14. Nagamatsu Y, Toda S, Koike T, Miyoshi Y, Shigematsu S, Kogure M: Cloning, sequencing, and expression of the Bombyx mori receptor for Bacillus thuringiensis insecticidal Cry1A(a) toxin. Biosci. Biotechnol. Biochem 1998, 62:727-734
15. Nagamatsu Y, Koike T, Sasaki K, Yoshimoto A, Furukawa Y: The cadherin-like protein is essential to specificity determination and cytotoxic action of the Bacillus thuringiensis insecticidal Cry1Aa toxin. FEBS Lett 1999, 460:385-390
16. Ihara H, Uemura T, Masuhara M, Ikawa S, Sugimoto S, Wadano A, Himeno M: Purification and partial amino acid sequences of the binding protein from Bombyx mori for Cry1Aa δ-endotoxin of Bacillus thuringiensis. Comp. Biochem. Physiol 1998, 120:197-204
17. Ikawa S, Tsuda Y, Fukada T, Sugimoto K, Himeno M: cDNA cloning of the Cry1Aa receptor variants from Bombyx mori and their expression in mammalian cells. Biosci, Biotechnol. Biochem 2000, 64:2682-2685
18. Vadlamudi RK, Weber E, Ji I, Ji TH, Bulla LA Jr: Cloning and expression of a receptor for an insecticidal toxin of Bacillus thuringiensis. J. Biol. Chem 1995, 270:5490-5494
19. Jenkins JL, Lee MK, Valaitis AP, Curtiss A, Dean DH: Bivalent sequential binding model of a Bacillus thuringiensis toxin to gypsy moth aminopeptidase N receptor. J. Biol. Chem 2000, 275:14423-14431
20. Gómez I, Oltean DI, Gill S, Bravo A, Soberón M: Mapping the epitope in cadherin-like receptors involved in Bacillus thuringiensis Cry1A toxins interaction using phage display. J. Biol. Chem 2001, 276:28906-28912
21. Yaoi K, Nakanishsi K, Kadotani T, Imamura M, Koizumi N, Iwahana H, Sato R: Bacillus thuringiensis Cry1Aa toxin binding region of Bombyx mori aminopeptidase N. FEBS Letts 1999, 463:221-224
22. Altschul SF, Madden TL, Schaffer AA, Zhang J, Zhang Z, Miller W, Lipman DJ: Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucl. Acids Res 1997, 25:3389-3402
23. Luo K, Sangadala S, Masson L, Mazza A, Brousseau R, Adang MJ: The Heliothis virescens 170 kDa aminopeptidase functions as "receptor A" by mediating specific Bacillus thuringiensis Cry1A δ-endotoxin binding and pore formation. Insect Biochem. Mol. Biol 1997, 27:735-743
24. Rajamohan F, Alzate O, Cotrill JA, Curtiss A, Dean DH: Protein engineering of Bacillus thuringiensis δ-endotoxin: mutations at domain II of Cry1Ab enhance receptor affinity and toxicity towards gypsy moth larvae. Proc. Natl. Acad. Sci. USA 1996, 93:14338-14343
25. Wolfersberger M, Lüthy P, Maurer A, Parenti P, Sacchi FV, Giordana B, Hanozet GM: Preparation and partial characterization of amino acid transporting brush border membrane vesicles from the larval midgut of the cabbage butterfly (Pieris brassicae). Comp. Biochem. Physiol 1987, 86A:301-308
26. Lee MK, Young BA, Dean DH: Domain III exchanges of Bacillus thuringiensis Cry1A toxins affect binding to different gypsy moth midgut receptors. Biochem. Biophys. Res. Commun 1995, 216:306-312
27. Lee MK, You TH, Young BA, Valaitis AP, Dean DH: Aminopeptidase N purified from gypsy moth BBMV is a specific receptor for Bacillus thuringiensis Cry1Ac toxin. Appl. Environ. Microbiol 1996, 62:2845-2849