Activation of the renin-angiotensin system in α-calcitonin gene-related peptide/calcitonin gene knockout mice

Journal of Hypertension

Volumn 22, Issue 7, 2004, Pages 1345-1349

  Li, Jianping ^a   Zhao, Huawei ^a   Supowit, Scott C ^b   DiPette, Donald J ^b   Wang, Donna H ^a,c  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

^c MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Angiotensin II receptor; Calcitonin; Calcitonin gene related peptide; Hypertension; Knockout mice; Renin

Indexed keywords

ALPHA CALCITONIN GENE RELATED PEPTIDE; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; CALCITONIN; LOSARTAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; HYPERTENSION; KIDNEY CORTEX; KIDNEY MEDULLA; KNOCKOUT GENE; KNOCKOUT MOUSE; MALE; MEAN ARTERIAL PRESSURE; MESENTERIC ARTERY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; WESTERN BLOTTING; WILD TYPE;

EID: 3042759512     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.hjh.0000125409.50839.f1     Document Type: Article

References (27)

1. Wimalawansa SJ. Calcitonin gene-related peptide: molecular genetics, physiology, pathology and therapeutic potentials. Endocrinol Rev 1996; 17:533-585.
2. Rosenfeld MG, Mermod JJ, Amara SG, Swanson LW, Sawchenko PE, Rivier J, et al. Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing. Nature 1983; 304:129-135.
3. Zaidi M, Breimer LH, MacIntyre I. Biology of peptides from the calcitonin genes. J Exp Physiol 1987; 72:371-408.
4. Amara SG, Arriza JL, Leff SE, Swanson LW, Evans RM, Rosenfeld MG. Expression in brain of a messenger RNA encoding a novel neuropeptide homologous to calcitonin gene-related peptide. Science 1985; 229:1094-1097.
5. Wimalawansa SJ, Morris HR, Etienne A, Blench I, Panico M, MacIntyre I. Isolation, purification and characterization of β-hCGRP from human spinal cord. Biochem Biophys Res Commun 1990; 167:993-1000.
6. Brain SD, Williams TJ, Tippins JR, Morris HR, MacIntyre I. Calcitonin gene-related peptide is a potent vasodilator. Nature 1985; 313:54-56.
7. Bell D, McDermott BJ. Calcitonin gene-related peptide in the cardiovascular system: characterization of receptor populations and their (patho)physiological significance. Pharmacol Rev 1996; 48:253-288.
8. DiPette DJ, Schwarzenberger K, Kerr N, Holland OB. Dose-dependent systemic and regional hemodynamic effects of calcitonin gene-related peptide. Am J Med Sci 1989; 297:65-70.
9. Oh-hashi Y, Shindo T, Kurihara Y, Imai T, Wang Y, Morita H, et al. Elevated sympathetic nervous activity in mice deficient in CGRP. Circ Res 2001; 89:983-990.
10. Gangula PR, Zhao H, Supowit SC, Wimalawansa SJ, DiPette DJ, Westlund KN, et al. Increased blood pressure in alpha-calcitonin gene-related peptide/calcitonin gene knockout mice. Hypertension 2000; 35:470-475.
11. Wang DH, Huang Y. Development of salt sensitive hypertension in a sensory denervated model: the underlying mechanisms. J Renin Angiotensin Aldosterone Syst 2001; 2:125-129.
12. Huang Y, Wang DH. Role of renin-angiotensin-aldosterone system in salt-sensitive hypertension induced by sensory denervation. Am J Physiol Heart Circ Physiol 2001; 281:H2143-H2149.
13. Huang Y, Wang DH. Role of AT1 and AT2 receptor subtypes in salt-sensitive hypertension induced by sensory nerve degeneration. J Hypertens 2001; 19:1841-1846.
14. Hoff AO, Catala-Lehnen P, Thomas PM, Priemel M, Rueger JM, Nasonkin I, et al. Increased bone mass is an unexpected phenotype associated with deletion of the calcitonin gene. J Clin Invest 2002; 110:1849-1857.
15. Hoff AO, Thomas PM, Cote GJ, Qiu H, Brain S, Puerner D, et al. Generation of a calcitonin knockout mouse model. Bone 1998; 23 (Suppl 5):S164.
16. Li XX, Bek M, Asico LD, Yang Z, Grandy DK, Goldstein DS, et al. Adrenergic and endothelin B receptor-dependent hypertension in dopamine receptor type-2 knockout mice. Hypertension 2001; 38:303-308.
17. Li J, Kaminski NE, Wang DH. Anandamide-induced depressor effect in spontaneously hypertensive rats: role of the vanilloid receptor. Hypertension 2003; 41:757-762.
18. Ballew JR, Fink GD. Role of endothelin ETB receptor activation in angiotensin II-induced hypertension: effects of salt intake. Am J Physiol Heart Circ Physiol 2001; 281:H2218-H2225.
19. Zhao HW, Fink G, DiPette DJ, Supowit SC. Telemetric recording of basal blood pressure and circadian ryhthm in alpha-calcitonin gene-related peptide knockout mice. Hypertension 2003; 42:40.
20. Preibisz JJ. CGRP and regulation of human cardiovascular homestasis. Am J Hypertens 1993; 6:434-450.
21. Yamada M, Ishikawa T, Fujimori A, Miyauchi T, Goto K. Enhanced depressor and hyperemic responses to calcitonin gene-related peptide in spontaneously hypertensive rats. Peptides 1998; 19:697-701.
22. Wang DH, Li J, Qiu J. Salt-sensitive hypertension induced by sensory denervation: introduction of a new model. Hypertension 1998; 32:649-653.
23. Siren AL, Feuerstein G. Cardiovascular effects of rat calcitonin gene-related peptide in the conscious rat. J Pharmacol Exp Ther 1988; 247:69-78.
24. Chin SY, Hall JM, Brain SD, Morton IK. Vasodilator responses to calcitonin gene-related peptide (CGRP) and amylin in the rat isolated perfused kidney are mediated via CGRP1 receptors. J Pharmacol Exp Ther 1994; 269:989-992.
25. Kurtz A, Muff R, Born W, Lundberg JM, Millberg BI, Gnadinger MP, et al. Calcitonin gene-related peptide is a stimulator of renin secretion. J Clin Invest 1988; 82:538-543.
26. Resnick LM, Churchill MC, Churchill PC, Laragh JH, Orlowski R. Effects of calcitonin, calcitonin analogues, and calcitonin gene-related peptide on basal in vitro renin secretion. Am J Hypertens 1989; 2:453-457.
27. Wang DH, Du Y, Yao A, Hu Z. Regulation of type 1 angiotensin II receptor and its subtype gene expression in kidney by sodium loading and angiotensin II infusion. J Hypertens 1996; 14:1409-1415.