Inhibition of glutathione S-transferases by thonningianin A, isolated from the African medicinal herb, Thonningia sanguinea, in vitro

Food and Chemical Toxicology

Volumn 42, Issue 9, 2004, Pages 1401-1408

  Gyamfi, Maxwell Afari ^a,d   Ohtani, Ikuko Ichiba ^b   Shinno, Etsuki ^c   Aniya, Yoko ^a  

^a Rhukyu University School of Medicine   (Japan)

^b Dept of Chem and Marine Science ^*  (Japan)

^c UNIVERSITY OF THE RYUKYUS   (Japan)

^d HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Antioxidant; Glutathione S transferase; Inhibition; Polyphenol; Thonningia sanguinea; Thonningianin A

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; 1,2 EPOXY 3 (4 NITROPHENOXY)PROPANE; ALKANE DERIVATIVE; CIBACRON BLUE F3GA; ETACRYNIC ACID; GLUTATHIONE; HEMATIN; PLANT EXTRACT; TANNIN; THONNINGIA SANGUINEA EXTRACT; THONNINGIANIN A; TRANSFERASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; DRUG ISOLATION; ENZYME ACTIVITY; HUMAN; LIVER; MALE; MEDICINAL PLANT; NONHUMAN; RAT; THONNINGIA SANGUINEA;

ANIMALS; ANTIOXIDANTS; BALANOPHORACEAE; CYTOSOL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GLUTATHIONE TRANSFERASE; HUMANS; HYDROLYZABLE TANNINS; INHIBITORY CONCENTRATION 50; LIVER; MALE; MEDICINE, AFRICAN TRADITIONAL; PLANTS, MEDICINAL; RATS; RATS, SPRAGUE-DAWLEY; TANNINS;

THONNINGIA; THONNINGIA SANGUINEA;

EID: 3042747926     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2004.04.001     Document Type: Article

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