Cross-linking of MHC class I molecules on human NK cells inhibits NK cell function, segregates MHC I from the NK cell synapse, and induces intracellular phosphotyrosines

Journal of Leukocyte Biology

Volumn 76, Issue 1, 2004, Pages 116-124

  Rubio, Gonzalo ^a   Férez, Xavier ^b   Sánchez Campillo, María ^b   Gálvez, Jesús ^c   Martí, Salvador ^a   Verdú, Rocío ^a   Hernández Caselles, Trinidad ^b   García Peñarrubia, Pilar ^b,d  

^a MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

^b UNIVERSITY OF MURCIA   (Spain)

^c Faculty of Science   (Spain)

^d Unit of Pharmacology   (Spain)

Author keywords

Cytotoxicity; E:T conjugation; Rafts colocalization

Indexed keywords

IMMUNOGLOBULIN FC FRAGMENT; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PHOSPHOTYROSINE; SPHINGOLIPID ACTIVATOR PROTEIN 1;

ADULT; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CELL KILLING; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CROSS LINKING; CYTOTOXICITY; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; LYMPHOCYTE FUNCTION; MAJOR HISTOCOMPATIBILITY COMPLEX; NATURAL KILLER CELL; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SYNAPSE;

ANTIBODIES, MONOCLONAL; CELL COMMUNICATION; CELL LINE; CROSS-LINKING REAGENTS; CYTOTOXICITY TESTS, IMMUNOLOGIC; FLUORESCENT ANTIBODY TECHNIQUE; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; KILLER CELLS, NATURAL; MEMBRANE MICRODOMAINS; MICROSCOPY, CONFOCAL; PHOSPHOTYROSINE; SIGNAL TRANSDUCTION;

EID: 3042738953     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.1103597     Document Type: Article

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