Isolation and characterization of a novel lepidopteran-selective toxin from the venom of South Indian red scorpion, Mesobuthus tamulus

BMC Biochemistry

Volumn 2, Issue , 2001, Pages 1-8

  Wudayagiri, Rajendra ^a,b   Inceoglu, Bora ^b   Herrmann, Rafael ^c   Derbel, Maher ^b   Choudary, Prabhakara V ^b   Hammock, Bruce D ^b  

^a SRI VENKATESWARA UNIVERSITY   (India)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c DUPONT COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INSECT VENOM; LEPIDOPTERAN; NEUROTOXIN; PEPTIDE; SCORPION VENOM; UNCLASSIFIED DRUG;

ALPHA HELIX; ARTICLE; BETA SHEET; FLACCID PARALYSIS; LARVA; NONHUMAN; PROTEIN CROSS LINKING; PROTEIN ISOLATION; PROTEIN STRUCTURE; SCORPION; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS; THREE DIMENSIONAL IMAGING;

BUTHUS; HELIOTHIS; HELIOTHIS VIRESCENS; INSECTA; LEPIDOPTERA; MAMMALIA; MESOBUTHUS TAMULUS; SCORPIONES;

EID: 3042727965     PISSN: 14712091     EISSN: None     Source Type: Journal    
DOI: 10.1186/1471-2091-2-16     Document Type: Article

References (42)

1. Rochat H, Bernard P, Couraud F: Scorpion toxins: Chemistry and mode of action. In: Adv. Cytopharmacol, Edited by Ceccarelli, F. pp. 325-334 New York: Raven; 1979
2. Zlotkin E, Eitan M, Bindokas VP, Adams ME, Moyer M, Burkhart W, Fowler E: Functional duality and structural uniqueness of depressant insect-selective neurotoxins. Biochemistry 1991, 30:4814-4821
3. Gordon D, Moskowitz H, Eitan M, Warner C, Catterall WA, Zlotkin E: Localization of receptor sites for insect-selective toxins on sodium channels by site-directed antibodies. Biochemistry 1992, 31:7622-7628
4. Zlotkin E, Miranda F, Rochat C: Chemistry and pharmacology of Buthinae scorpion venoms. In: Arthropod Venoms Edited by Bettini, S. pp. 317-369 New York: Springer-Verlag; 1978
5. Carbone E, Wanke E, Prestipino G, Possani LD, Maelicke A: Selective blockage of voltage-dependent K+ channels by a novel scorpion toxin. Nature 1982, 296:90-91
6. Miller C, Moczydlowski E, Latore R, Philips M: Charybdotoxin, a potent inhibitor of single Ca2+-activated K+ channels from mammalian skeletal muscle. Nature 1985, 313:316-318
7. Jover E, Couraud F, Rochat H: Two types of scorpion neurotoxins characterized by their binding to two separate receptor sites on rat brain synaptosomes. Biochem. Biophys. Res. Commun 1980, 95:1607-1614
8. Couraud F, Jover E, Dubois JM, Rochat H: Two types of scorpion toxin receptor sites, one related to the activation, the other to the inactivation of the action potential sodium channel. Toxicon 1982, 20:9-16
9. Zlotkin E, Moskowitz H, Herrmann R, Pelhate M, Gordon D: Insect sodium channel as the target for insect-selective neurotoxins from scorpion venom. In: Molecular Action of Insecticides on Ion Channels, Edited by dark, J.M. pp. 56-85 Washington, D.C.: ACS; 1995
10. Delepierre M, Prochnicka A, Possani LD: A novel potassium channel blocking toxin from the scorpion Pandinus imperator: Al H NMR analysis using a nano-NMR probe. Biochemistry 1997, 36:2649-2658
11. DeBin JA, Maggio JE, Strichartz GR: Purification and characterization of chlorotoxin, a Cl- channel ligand from the venom of the scorpion. Am. J. Physiol. Cell. Physiol 1993, 264:C361-C369
12. Stewart LMD, Hirst M, Ferber ML, Merryweather AT, Cayley PJ, Posse RD: Construction of an improved baculovirus insecticide containing an insect-specific toxin gene. Nature 1991, 352:85-88
13. McCutchen BF, Hammock BD: Recombinant baculovirus expressing an insect-selective neurotoxin. In: Natural and Engineered Pest Management Agents, Edited by Hedin PA, Menn JJ, Hollingworth RM. pp. 348-367 Washington, D.C: American Chemical Society Symp. Ser 1994
14. Zlotkin E: The insect voltage-gated sodium channel as target of insecticides. Ann. Rev. Entomol 1999, 44:429-455
15. Nakagawa Y, Lee YM, Lehmberg E, Herrmann R, Herrmann R, Moskowitz H, Jones AD, Hammock BD: Anti-insect toxin 5 (AalT5) from A australis. Eur. J. Biochem 1997, 246:496-501
16. Crest M, Jacquet G, Gola M, Zerrouk H, Benslimane A, Rochat H, Mansuelle P, Martin-Eauclaire MF: Kaliotoxin, a novel peptidyl inhibitor of neuronal BK-type Ca2+-activated K+ channels characterized from Androctonus mauretanicus mauretanicus venom. J. Biol. Chem 1992, 267:1640-1647
17. Bontems F, Roumestand C, Gilquin B, Me'nez A, Toma F: Refined structure of chary bdotoxin: common motifs in scorpion toxins and insect defensins. Science 1991, 254:1521-1523
18. Becerril B, Corona M, Garcia C, Bolivar F, Possani LD: Cloning of genes encoding scorpion toxins: An interpretive review. J. Toxicol. Toxin Rev 1995, 14:339-357
19. Chhatwal GS, Heberman E: Neurotoxins, protease inhibitors and histamine releasers in the venom of the Indian Red scorpion (Buthus tamulus): Isolation and partial characterization. Toxicon 1981, 19:807-823
20. Lala K, Narayanan P: Purification, N-terminal sequence and structural characterization of a toxic protein from the Indian scorpion venom, Buthus tamulus. Toxicon 1994, 32:325-338
21. Galvez A, Gimenez-Gallego G, Reuben JP, Roy-Contancin L, Feigenbaum P, Kaczorowski GJ, Garcia ML: Purification and characterization of a unique, potent, peptidyl-probe for the high-conductance calcium-activated potassium channel from the venom of the scorpion, Buthus tamulus. J. Biol. Chem 1990, 265:11083-11090
22. Arseniev AS, Kondakov VI, Maioro VN, Bystrov VF: NMR solution spatial structure of "short" insectotoxin 15A. Febs. Lett 1984, 165:57-62
23. Grishin EV, Volkova TM, Soldatova LN: Study of toxic components from the venom of Caucasus subspecies of scorpion Buthus eupeus. Bioorg. Khim 1982, 8:155-164
24. Adamovich TB, Nasimov IV, Grishin EV, Ovchinnikov YA: Amino acid sequence of insectotoxin II from the venom of middle-asian scorpion Buthus eupeus. Bioorg. Khim 1977, 3:485-493
25. Fazal A, Beg OU, Shafqat J, Zaidi ZH, Jornvall H: Characterization of two different peptides from the venom of the scorpion Buthus sindicus. Febs. Lett 1989, 257:260-262
26. Rosso JP, Rochat H: Characterization of ten proteins from the venom of the Moroccan scorpion Androctonus mauretanicus mauretanicus, six of which are toxic to mouse. Toxicon 1985, 23:113-125
27. Adjadj E, Naudat V, Quiniou E, Wouters D, Sautiere P, Craeseu CT: Solution structure of Lqh-8/6, a toxin-like peptide from a scorpion venom-structural homogeneity induced by proline cis/trans isomerization. Eur. J. Biochem 1997, 246:218-227
28. Altschul SF, Madden TL, Schaeffer AA, Zhang J, Zhang Z, Miller W, Lipman DJ: Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res 1997, 25:3389-3402
29. Drenth J, Low BW, Richardson JS, Wright CS: The toxin-agglutinin fold. A new group of small protein structures organized around a four-disulfide core. J. Biol. Chem 1980, 255:2652-2655
30. Drenth J: The structure of neurophysin. J. Biol. Chem 1981, 256:2601-2602
31. Johnson BA, Sugg EE: Determination of the three-dimensional structure of iberiotoxin in solution by 1 H Nuclear magnetic resonance spectroscopy. Biochemistry 1992, 31:8151-8159
32. Fernandez I, Romi R, Szendeffy S, Martin-Eauclaire MF, Rochat H, Rietschoten JV, Pons M, Giralt E: Kaliotoxin (1-37) shows structural differences with related potasium channel blockers. Biochemistry 1994, 33:14256-14263
33. Aiyar J, Withka JM, Rizzi JP, Singleton DH, Andrews GC, Lin W, Boyd J, Hanson DC, Simon M, Dethlefs B, Lee CL, Hall JE, Gutman GA, Chandy KG: Topology of the pore-region of a K+ channel revealed by the NMR-derived structures of scorpion toxins. Neuron 1995, 15:1169-1181
34. Johnson BA, Stevens SP, Williamson JM: Determination of the three-dimensional structure of margatoxin by 1H, 13C, 15N triple-resonance nuclear resonance magnetic spectroscopy. Biochemistry 1994, 33:15061-15070
35. Kharrat R, Mansuelle P, Sampieri F, Crest M, Oughideni R, Rietschoten JV, Martin-Eauclaire MF, Rochat H, Ayub ME: Maurotoxin, a four disulfide bridge toxin from Scorpio maurus venom: Purification, structure and action on potassium channels. Febs. Lett 1997, 406:284-290
36. Krezel AM, Kasibhatla C, Hidalgo P, Mackinnon R, Wagner G: Solution structure of the K+ channel inhibitor agitoxin2: Caliper for probing channel geometry. Protein. Sci 1995, 4:1478-1489
37. Dauplais M, Gilquin B, Possani LD, Gurrola-Briones G, Roumestand C, Menez A: Determination of the three-dimensional solution structure of noxiustoxin: analysis of structural differences with related short-chain scorpion toxins. Biochemistry 1995, 34:16563-16573
38. Lippens G, Najib S, Wodak J, Tartar A: NMR sequential assignments and solution structure of chlorotoxin, a small scorpion that blocks chloride channels. Biochemistry 1995, 34:13-21
39. Guex N, Peitsch MC: SWISS-model and the SWISS-PDB viewer: An environment for comparative protein modeling. Electrophoresis 1997, 18:2714-2723
40. Peitsch MC: Protein modeling by Email. Bio/Technology 1995, 13:658-660
41. Peitsch MC: ProMod and SWISS-Model: Internet-based tools for automated comparative protein modeling. Biochem. Soc. Trans 1996, 24:274-279
42. Peitsch MC, Guex N: Large scale comparative protein modeling. In: Proteome research: New frontiers in functional genomics, Edited by Wilkins MR, Williams KL, Appel RD, Hochstrasser DF. pp. 177-186 Berlin: Springer-Verlag; 1997