Performance characteristics of the Coulter LH 500 hematology analyzer

Laboratory Hematology

Volumn 10, Issue 2, 2004, Pages 76-87

  Kaplan, Sandra S ^a   Johnson, Kathleen ^a   Wolfe, Nancy ^a   Brown, Wendy ^b   Keeney, Michael ^b   Gray Statchuk, Leslie ^b   Yee, Ian Chin ^b  

^a PRESBYTERIAN UNIVERSITY HOSPITAL   (United States)

^b LONDON HEALTH SCIENCES CENTRE   (Canada)

Author keywords

Automated analysis; Hematology analyzer; LH 500; Performance evaluation

Indexed keywords

ARTICLE; AUTOANALYZER; BASOPHIL; BLOOD ANALYSIS; BLOOD CELL COUNT; BLOOD SAMPLING; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CORRELATION COEFFICIENT; COST EFFECTIVENESS ANALYSIS; DIAGNOSTIC ACCURACY; ERYTHROCYTE COUNT; FLOW CYTOMETRY; HUMAN; INTERMETHOD COMPARISON; LABORATORY DIAGNOSIS; LEUKOCYTE DIFFERENTIAL COUNT; RANK SUM TEST; SENSITIVITY AND SPECIFICITY; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; VALIDATION PROCESS;

BLOOD CELL COUNT; EFFICIENCY; EVALUATION STUDIES; FALSE NEGATIVE REACTIONS; HUMANS; QUALITY CONTROL; REFERENCE STANDARDS; REFERENCE VALUES; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 3042723944     PISSN: 10802924     EISSN: None     Source Type: Journal    
DOI: 10.1532/LH96.04019     Document Type: Article

References (19)

1. Vamvakas EC. Meta-analysis of studies of the diagnostic accuracy of laboratory tests. A review of concepts and methods. Arch Pathol Lab Medicine. 1998;122:675-686.
2. Lundberg GD. Acting on significant laboratory results. JAMA. 1981;245:1762-1763.
3. Burke DM. Laboratory medicine in the 21st century. Am J Clin Pathol. 2000;114:840-846.
4. Morrow JS. Fifty years of laboratory investigation. Chronicle of a blossoming discipline. Lab Invest. 2002;82:3-4.
5. Connelly DP, Sielaff BH, Willard KE. A clinician workstation for improving laboratory use. Integrated display of laboratory results. Am J Clin Pathol. 1995;104:243-252.
6. Gulati GL, Hyun BH. The automated CBC: a current perspective. Hematol Oncol Clin N A. 1994;8:593-603.
7. Ward PC. The CBC at the turn of the millennium: an overview. Clin Chem. 2000;46:1215-1220.
8. Bodey GP, Buckley M, Sathe YS, Freireich EJ. Quantitative relationship between circulating leukocytes and infection in patients with acute leukemia. Ann Int Med. 1966;64:328-340.
9. Harrison P. Progress in assessment of platelet function. Brit J Hematol. 2000;111:733-744.
10. Houwen B. Fifty years of hematology innovation: The Coulter Principle. MLO. 2003;35:12-13.
11. Lantis KL, Harris RJ, Davis G, Renner N, Finn WG. Elimination of instrument-driven reflex manual differential leukocyte counts. Optimization of manual blood smear review criteria in a high-volume automated hematology laboratory. Am J Clin Pathol. 2003;119:656-662.
12. Connelly DP, Willard KE, Hallgren MJH, Sielaff BH. Closing the clinical laboratory testing loop with information technology. Am J Clin Pathol. 1996;105 (suppl 1):S40-47.
13. Brown W, Kaplan S, Keeney M, Johnson K, Wolfe N, Chin-Yee I. Workflow improvement with random access and enhanced flagging on the new Coulter LH 750 hematology analyzer. Lab Hematol. 2001;7:229-235.
14. Chin Yee I, Keeney M, Johnson K, Brown W, Wolfe N, Kaplan S. White blood cell flagging rates of the Coulter LH 750 analyzer compared with the Coulter Gen•S hematology analyzer. Lab Hematol. 2001;7:211-216.
15. Keeney M, Brown W, Chin Yee I. Platelet counts and flagging rates from the LH 750 hematology analyzer compared with the ICSH/ISLH platelet reference method and the Gen•S hematology analyzer. Lab Hematol. 2001;7:204-210.
16. Kaplan S, Johnson K, Wolfe N. Validation of low platelet counts from Coulter LH 750 and Coulter Gen•S analyzers. Lab Hematol. 2001;7:198-203.
17. International Council for Standardization in Haematology Expert Panel on Cytometry and International Society of Laboratory Hematology Task Force on Platelet Counting. Platelet counting by the RBC/platelet ratio method. A reference method. Am J Clin Pathol. 2001;115:460-464.
18. Davis BH, Bigelow NC. Indirect immunoplatelet counting by flow cytometry as a reference method for platelet count calibration. Lab Hematol. 1999;5:15-21.
19. Reference Leukocyte Differential Count (Proportional) and Evaluation of Instrumental Methods. NCCLS Document H20-A. March 1992.