Baculoviruses expressing the human familial Alzheimer's disease presenilin 1 mutation lacking exon 9 increase levels of an amyloid beta-like protein in Sf9 cells

Molecular Psychiatry

Volumn 9, Issue 6, 2004, Pages 594-602

  Verdile, G ^a   Groth, D ^a   Mathews, P M ^b   St George Hyslop, P ^c,d   Fraser, P E ^c,d   Ramabhadran, T V ^e   Kwok, J B J ^f   Schofield, P R ^f,g   Carter, T ^h   Gandy, S ^h   Martins, R N ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

^c UNIVERSITY OF TORONTO   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

^e Tranzyme Inc   (United States)

^f GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^g UNIVERSITY OF NEW SOUTH WALES   (Australia)

^h THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

secretase; A ; Alzheimer's disease; Amyloid precursor protein; Amyloid ; Nicastrin; Presenilin 1; Proteolytic processing; Spodoptera frugiperda cells

Indexed keywords

AMYLOID BETA PROTEIN; MEMBRANE PROTEIN; MUTANT PROTEIN; NICASTRIN; PRESENILIN 1; TROPOMYOSIN;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; BACULOVIRUS EXPRESSION SYSTEM; CONTROLLED STUDY; EXON; GENE MUTATION; INSECT CELL; LEPIDOPTERA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; BACULOVIRIDAE; CELL LINE; EXONS; HUMANS; MEMBRANE PROTEINS; PRESENILIN-1; RECOMBINANT PROTEINS; SEQUENCE DELETION; SPODOPTERA; TRANSFECTION;

EID: 3042701268     PISSN: 13594184     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.mp.4001458     Document Type: Article

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