Aberrant expression of a fetal glycoprotein 68 in hepatocellular carcinoma: A comparative study on the expression of alpha-fetoprotein and carcinoembryonic antigen

Histology and Histopathology

Volumn 19, Issue 3, 2004, Pages 701-706

  Kato, Masako ^a   Shinozawa, T ^b   Kato, S ^c   Terada, T ^d  

^a TOTTORI UNIVERSITY HOSPITAL   (Japan)

^b GUNMA UNIVERSITY   (Japan)

^c TOTTORI UNIVERSITY   (Japan)

^d Shimizu Municipal Hospital   (Japan)

Author keywords

fetoprotein; Carcinoembryonic antigen; Fetal glycoprotein 68; Hepatocellular carcinoma; Immunohistochemistry

Indexed keywords

ALPHA FETOPROTEIN; CARCINOEMBRYONIC ANTIGEN; FORMALDEHYDE; GLYCOPROTEIN; GLYCOPROTEIN GP 68; IMMUNOGLOBULIN G ANTIBODY; PARAFFIN; UNCLASSIFIED DRUG;

ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ARTICLE; CANCER CELL; CANCER STAGING; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOPLASM; EMBRYO; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INTERMETHOD COMPARISON; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RAT; TISSUE SECTION; TUMOR CELL;

ADULT; AGED; ALPHA-FETOPROTEINS; ANIMALS; ANTIBODIES, MONOCLONAL; CARCINOEMBRYONIC ANTIGEN; CARCINOMA, HEPATOCELLULAR; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LIVER NEOPLASMS; MALE; MICE; MICE, INBRED BALB C; MIDDLE AGED; MOLECULAR WEIGHT; PREGNANCY; RATS; RATS, WISTAR; RETROSPECTIVE STUDIES;

ANIMALIA;

EID: 3042699814     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Abelev G.I., Perova S.D., Khramkova N.I., Postnikova Z.A. and Irlin I.S. (1963). Production of embryonal alpha-globulin by transplantable mouse hepatomas. Transplantation 1, 174-180.
2. Alexander P. (1972). Foetal "antigens" in cancer. Nature 235, 137-140.
3. Aoyagi Y., Ikenaka T. and Ichida F. (1978). Copper(II)-binding ability of human α-fetoprotein. Cancer Res. 38, 3483-3486.
4. Aoyagi Y., Ikenaka T. and Ichida F. (1979). α-fetoprotein as a carrier protein in plasma and its bilirubin-binding ability. Cancer Res. 39, 3571-3574.
5. Aoyagi Y., Takahashi Y., Odani S., Ogata K., Ono T. and Ichida F. (1982). Inhibitory effect of α-fetoprotein on protein synthesis in a reticulocyte lysate cell-free system. J. Biol. Chem. 257, 9566-9569.
6. Balaton A.J., Nehama-Sibony M., Gotheil C., Callard P. and Baviera E.E. (1988). Distinction between hepatocellular carcinoma, cholangiocarcinoma, and metastatic carcinoma based on immunohistochemical staining for carcinoembryonic antigen and for cytokeratin 19 on paraffin sections. J. Pathol. 156, 305-310.
7. Burnette W.N. (1981). "Western blotting": Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A. Anal. Biochem. 112, 195-203.
8. Edmondson H.A. and Steiner P.E. (1954). Primary carcinoma of the liver. A study of 100 cases among 48900 necropsies. Cancer 7, 462-503.
9. Fujita S.C., Zipursky S.L., Benzer S., Ferrüs A. and Shotwell S.L. (1982) Monoclonal antibodies against the Drosophila nervous system. Proc. Natl. Acad. Sci. USA 79, 7929-7933.
10. Gold P. and Freedman S.O. (1965). Specific carcinoembryonic antigens of the human digestive system. J. Exp. Med. 122, 467-481.
11. Hawkes R., Niday E. and Gordon J. (1982). A dot-immunobinding assay for monoclonal and other antibodies. Anal. Biochem. 119, 142-147.
12. Hsu S.M., Rains L. and Fanger H. (1981). Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: A comparison between ABC and unlabeled antibody (PAP) procedures. J. Histochem. Cytochem. 29, 577-580.
13. Imoto M., Nishimura D., Fukuda Y., Sugiyama K., Kumada T. and Nakano S. (1985). Immunohistochemical detection of a-fetoprotein, carcinoembryonic antigen, and ferritin in formalin-paraffin sections from hepatocellular carcinoma. Am. J. Gastroenterol. 80, 902-906.
14. Ishak K.G., Goodman Z.D. and Stocker J.T. (2001). Tumors of the liver and intrahepatic bile ducts. Rosai J. and Sobin L,H. (eds). Atlas of tumor pathology. Third series, Washington DC, Armed Forces Institute of Pathology 2001, 199-230.
15. Kato S., Shinozawa T.,Nagashige H., Nakamura M., Asano Y., Takikawa M., Kato M., Awaya A., Hirano A. and Ohama E. (2002). Monoclonal antibody to stage-specific fetal brain 68-kDa glycoprotein (FGP66) revealed increased FGP68 expression in human primary brain tumors. Acta Neuropathol. 104, 57-66.
16. Köhler G. and Milstein C. (1975). Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 256, 495-497.
17. Kojiro M., Kawano Y., Isomura T. and Nakashima T. (1981). Distribution of albumin- and/or α-fetoprotein-positive cells in hepatocellular carcinoma. Lab. Invest. 44, 221-226.
18. Marks A., Sutherland D.R., Bailey D., Iglesias J., Law J., Lei M., Yeger H., Banerjee D. and Baumal R. (1999). Characterization and distribution of an oncofetal antigen (M2A antigen) expressed on testicular germ cell tumours. Br. J. Cancer, 80, 569-578.
19. Minami S., Furui J. and Kanematsu T. (2001). Role of carcinoembryonic antigen in the progression of colon cancer cells that express carbohydrate antigen. Cancer Res. 61, 2732-2735.
20. Morita T., Shinozawa T., Nakamura M., Awaya A., Sato N., Ishiwata I. and Kami K. (1998). Expression of a 68kDa-glycoprotein (GP68) and laminin in the mesodermal tissue of the developing mouse embryo. Okajima Folia Anat. Jpn. 75, 185-196.
21. Murgita R.A. and Tomasi T.B. Jr. (1975a). Suppression of the immune response by α-fetoprotein. I. The effect of mouse a-fetoprotein on the primary and secondary antibody response. J. Exp. Med. 141, 269-286.
22. Murgita R.A. and Tomasi T.B. Jr. (1975b). Suppression of the immune response by a-fetoprotein. II. The effect of mouse α -fetoprotein on mixed lymphocyte reactivity and mitogen-induced lymphocyte transformation. J. Exp. Med. 141, 440-452.
23. Noguchi S., Ogata S., Sato M. and Muramatsu T. (1984). Stage-specific polypeptides in the developing mouse brain as demonstrated by two-dimensional gel electrophoresis. J. Biochem. 96, 881-886.
24. Oikawa S., Inuzuka C., Kuroki M., Matsuoka Y., Kosaki G. and Nakazato H. (1989). Cell adhesion activity of non-specific cross-reacting antigen (NCA) and carcinoembryonic antigen (CEA) expressed on CHO cell surface: homophilic and heterophilic adhesion. Biochem. Biophys. Res. Commun. 164, 39-45.
25. Ritchie A.C. (1990). Neoplasia. In: Boyd's Textbook of Pathology. Ritchie A.C. (ed). 9th ed. Vol. I. London, Lea&Febiger, 1990: 234-278.
26. Rosai J. (1996). Special techniques in surgical pathology. Ackerman's Surgical Pathology. 8th ed. Vol 1. Ritchie A.C. (ed). Mosby-Year Book, Inc. St Louis, MO.. p 37.
27. Starzynska T., Wiechowska-Kozlowska A., Marlicz K., Bromley M., Robert S.A., Lawniczak M., Kolodziej B., Zyluk A. and Stern P.L. (1998). 5T4 oncofetal antigen in gastric carcinoma and its clinical significance. Eur. J. Gastroenterol. Hepatol. 10, 479-484.
28. Thung S.N., Gerber M.A., Sarno E. and Popper H. (1979). Distribution of five antigens in hepatocellular carcinoma. Lab. Invest, 41, 101-105.
29. Tsung S.H. (1977). Localization of α-fetoprotein synthesis in malignancies other than hepatoma. Arch. Pathol. Lab. Med. 101, 572-574.
30. Ueda K., Iwahashi M., Nakamori M., Nakamura M., Matsuura I., Yamaue H. and Tanimura H. (2001). Carcinoembryonic antigen-specific suicide gene therapy of cytosine deaminase/5-fluorocytosine enhanced by the cre/loxP system in the orthotopic gastric carcinoma model. Cancer Res. 61, 6158-6162.
31. Ureil J., de Nechaud B. and Dupiers M. (1972). Estrogen-binding properties of rat, mouse and man fetospecific serum protein. Demonstration by immunoautoradiographic methods. Biochem. Biophy. Res. Commun. 46, 1175-1180.
32. Vollmer C.M., Eilber F.C., Butterfield L.H., Ribas A., Dissette V.B., Koh A., Montejo L.D., Lee M.C., Andrews K.J., McBride W.H., Glaspy J.A. and Economou J.S. (1999). Alpha-fetoprotein-specific genetic immunotherapy for hepatocellular carcinoma. Cancer Res. 59, 3064-3067.
33. Wang X.W. and Xie H. (1999). Alpha-fetoprotein enhances the proliferation of human hepatoma cells in vitro. Life Sci. 64, 17-23.
34. Wunderlich H., Reichelt O., Zermann D.H., Schubert J., Berndt A. and Kosmehl H. (2001). Fetal fibronectin: a new screening-marker for bladder cancer? Oncol. Rep. 8, 669-672.
35. Zelle-Rieser C., Barsoum A.L., Sallusto F., Ramoner R., Rohrer J.W., Holtl L., Bartsch G., Coggin J.H. Jr. and Thurnher M. (2001). Expression and immunogenicity of oncofetal antigen-immature laminin receptor in human renal cell carcinoma. J. Urol. 165, 1705-1709.