Obligatory role for endogenous endothelin in mediating the hypertrophic effects of phenylephrine and angiotensin II in neonatal rat ventricular myocytes: Evidence for two distinct mechanisms for endothelin regulation

Journal of Pharmacology and Experimental Therapeutics

Volumn 310, Issue 1, 2004, Pages 43-51

  Xia, Ying ^a   Karmazyn, Morris ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; ANGIOTENSIN II [1 SARCOSINE 8 ISOLEUCINE]; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ENDOTHELIN 1; ENDOTHELIN A RECEPTOR ANTAGONIST; ENDOTHELIN B RECEPTOR ANTAGONIST; MITOGEN ACTIVATED PROTEIN KINASE; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE; PHENYLEPHRINE; PHOSPHORAMIDON; PRAZOSIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME IMMUNOASSAY; GENE EXPRESSION; HEART HYPERTROPHY; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANGIOTENSIN II; ANIMALS; ANIMALS, NEWBORN; ASPARTIC ENDOPEPTIDASES; ENDOTHELIN-1; ENDOTHELINS; GENE EXPRESSION; HEART VENTRICLES; HYPERTROPHY; METALLOENDOPEPTIDASES; MITOGEN-ACTIVATED PROTEIN KINASES; MUSCLE CELLS; MYOCARDIUM; PHENYLEPHRINE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; RECEPTORS, ENDOTHELIN;

EID: 3042692450     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.104.065185     Document Type: Article

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