Rhabdomyolysis caused by Commiphora mukul, a natural lipid-lowering agent

Annals of Pharmacotherapy

Volumn 38, Issue 7-8, 2004, Pages 1222-1225

  Bianchi, Antonio ^a   Cantù, Paola ^b   Firenzuoli, Fabio ^c   Mazzanti, Gabriela ^d   Menniti Ippolito, Francesca ^e   Raschetti, Roberto ^e  

^a Centro di Orientamento Educativo   (Italy)

^b Gallarate Hospital   (Italy)

^c SAN GIUSEPPE HOSPITAL   (Italy)

^d SAPIENZA UNIVERSITY OF ROME   (Italy)

^e ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

Commiphora mukul; Guggul; Herbal supplements; Rhabdomyolysis

Indexed keywords

3 HYDROXY 3 METHYLGLUTARYL COENZYME A; ALANINE AMINOTRANSFERASE; ANTILIPEMIC AGENT; ASPARTATE AMINOTRANSFERASE; CHOLESTEROL; COMMIPHORA MUKUL EXTRACT; CREATINE KINASE; FIBRIC ACID DERIVATIVE; HEMOGLOBIN; HERBACEOUS AGENT; LACTATE DEHYDROGENASE; NATURAL PRODUCT; PLANT EXTRACT; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CASE REPORT; COMMIPHORA; DRUG MEGADOSE; DRUG WITHDRAWAL; HEMOGLOBINURIA; HUMAN; LABORATORY TEST; MALE; NONHUMAN; PRIORITY JOURNAL; RARE DISEASE; RHABDOMYOLYSIS; SIDE EFFECT;

ANTILIPEMIC AGENTS; COMMIPHORA; HUMANS; HYPERCHOLESTEROLEMIA; MALE; MIDDLE AGED; PHYTOTHERAPY; PLANT EXTRACTS; RHABDOMYOLYSIS;

EID: 3042692069     PISSN: 10600280     EISSN: None     Source Type: Journal    
DOI: 10.1345/aph.1D486     Document Type: Article

References (27)

1. Warren JD, Blumbergs PC, Thompson PD. Rhabdomyolysis: a review. Muscle Nerve 2002;25:332-47.
2. Pasternak RC, Smith SC, Bairey-Merz CN, Grundy SM, Cleeman JI, Lenfant C. ACC/AHA/NHLBI clinical advisory on the use and safety of statins. J Am Coll Cardiol 2002;40:567-72.
3. Sauret JM, Marinides G, Wang GK. Rhabdomyolysis. Am Fam Physician 2002;65:907-12.
4. Holt S, Moore K. Pathogenesis of renal failure in rhabdomyolysis: the role of myoglobin. Exp Nephrol 2000;8:72-6.
5. van der Elst ME, Buurma H, Bouvy ML, de Boer A. Drug therapy for prevention of recurrent myocardial infarction. Ann Pharmacother 2003; 37:1465-77. DOI 10.1345/aph.1C450
6. Thompson PD, Clarkson P, Karas RH. Statin-associated myopathy. JAMA 2003;289:1681-90.
7. Omar MA, Wilson JP, Cox TS. Rhabdomyolysis and HMG-CoA reductase inhibitors. Ann Pharmacother 2001;35:1096-107. DOI 10.1345/aph. 10228
8. Capasso F, Gaginella TS, Grandolini G, Izzo AA. Are the herbal medicines safe? In: Phytotherapy-a quick reference to herbal medicine. Milan: Springer, 2003:13-20.
9. Satyavati GV. Gum guggul (Commiphora mukul)-the success story of an ancient insight leading to a modern discovery. Indian J Med Res 1988;87:327-35.
10. Khanna DS, Agarwal OP, Gupta SK, Arora RB. A biochemical approach to anti-atherosclerotic action of Commiphora mukul: an Indian indigenous drug in Indian domestic pigs (Sus scrofa). Indian J Med Res 1969; 57:900-6.
11. Verma SK, Bordia A. Effect of Commiphora mukul (gum guggulu) in patients of hyperlipidemia with special reference to HDL-cholesterol. Indian J Med Res 1988;87:356-60.
12. Nityanand S, Srivastava JS, Asthana OP. Clinical trials with gugulipid: a new hypolipidemic agent. J Assoc Physicians India 1989;37:323-8.
13. Singh RB, Niaz MA, Ghosh S. Hypolipidemic and antioxidant effects of Commiphora mukul as adjunct to dietary therapy in patients with hypercholesterolemia. Cardiovasc Drugs Ther 1994;8:659-64.
14. Szapary PO, Wolfe ML, Bloedon LT, Cucchiara AJ, DerMardersian AH, Ciriglia MD, et al. Guggulipid for the treatment of hypercholesterolemia: a randomized controlled trial. JAMA 2003;290:765-72.
15. Tripathi YB, Malhotra OP, Tripathi SN. Thyroid stimulating action of Z-guggulsterone obtained from Commiphora mukul. Planta Med 1984;1: 78-80.
16. Panda S, Kar A. Gugulu (Commiphora mukul) induces triiodothyronine production: possible involvement of lipid peroxidation. Life Sci 1999;65: PL137-41.
17. Wu J, Xia C, Meier J, Li S, Hu X, Lala DS. The hypolipidemic natural product guggulsterone acts as an antagonist of the bile acid receptor. Mol Endocrinol 2002;16:1590-7.
18. Urizar NL, Moore DD. Gugulipid: a natural cholesterol-lowering agent. Annu Rev Nutr 2003;23:303-13.
19. Thompson CJS, Ernst E. Herbs for serum cholesterol reduction: a systematic review. J Fam Pract 2003;52:468-78.
20. Dalvi SS, Nayak VK, Pohujani SM, Desai NK, Kshirsagar NA, Gupta KC. Effect of gugulipid on bioavailability of diltiazem and propranolol. J Assoc Physicians India 1994;42:454-5.
21. Naranjo CA, Busto U, Sellers EM, Sandor P, Ruiz I, Roberts EA, et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 1981;30:239-45.
22. Prasad GVR, Wong T, Meliton G, Bhaloo S. Rhabdomyolysis due to red yeast rice (Monascuspurpureus) in a renal transplant recipient. Transplantation 2002;74:1200-1.
23. Firenzuoli F, Gori L. Licorice induced rhabdomyolysis. Recent Progress in Medicine 2002;93:482-3.
24. Maglich JM, Sluder AE, Wilson TM, Moore JT. Beyond the human genome. Examples of nuclear receptor analysis in model organism and potential for drug discovery. Am J Pharmacogenom 2003;3:345-53.
25. Akiyama TE, Gonzalez FJ. Regulation of P450 genes by liver-enriched transcription factors and nuclear receptors. Biochim Biophys Acta 2003;1619:223-34.
26. Ernst E. Harmless herbs? A review of the recent literature. Am J Med 1998;104:170-8.
27. Fugh-Berman A, Ernst E. Herb-drug interactions: review and assessment of report reliability. Br J Clin Pharmacol 2001;52:587-95.