Effects of triiodothyronine on 5-HT1A and 5-HT1B autoreceptor activity, and postsynaptic 5-HT1A receptor activity, in rat hypothalamus: Lack of interaction with imipramine

Psychoneuroendocrinology

Volumn 29, Issue 9, 2004, Pages 1172-1183

  Gur, Eitan ^a   Lifschytz, Tsuri ^a   Van De Kar, Louis D ^b   Lerer, Bernard ^a   Newman, Michael E ^a  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^b LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

5 HT 1B receptor; 5 HT1A receptor; ACTH; Antidepressant; Corticosterone; Hypothalamus; Triiodothyronine

Indexed keywords

IMIPRAMINE; LIOTHYRONINE; SEROTONIN 1A RECEPTOR; SEROTONIN 1B RECEPTOR; TRICYCLIC ANTIDEPRESSANT AGENT;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; CORTICOTROPIN BLOOD LEVEL; DRUG EFFECT; DRUG POTENTIATION; HYPOTHALAMUS; IN VIVO STUDY; MALE; MICRODIALYSIS; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR SENSITIVITY; SEROTONIN BRAIN LEVEL; SEROTONIN RELEASE; SEROTONINERGIC SYSTEM;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ADRENOCORTICOTROPIC HORMONE; ANALYSIS OF VARIANCE; ANIMALS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; AUTORECEPTORS; CORTICOSTERONE; DRUG INTERACTIONS; HYPOTHALAMUS; IMIPRAMINE; MALE; MICRODIALYSIS; MICROINJECTIONS; RATS; RATS, INBRED STRAINS; RECEPTOR, SEROTONIN, 5-HT1A; RECEPTOR, SEROTONIN, 5-HT1B; SEROTONIN AGONISTS; SYNAPTIC TRANSMISSION; TRIIODOTHYRONINE;

EID: 3042690048     PISSN: 03064530     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2004.01.011     Document Type: Article

References (44)

1. Altshuler L.L., Bauer M., Frye M.A., Gitlin M.J., Mintz J., Szuba M.P., Leight K.L., Whybrow P.C. Does thyroid supplementation accelerate tricyclic antidepressant response? A review and meta-analysis of the literature. Am. J. Psychiatr. 158:2001;1617-1622
2. Anderson I.M., Deakin J.F.W., Miller H.E.J. The effect of chronic fluvoxamine on hormonal and psychological responses to buspirone in normal volunteers. Psychopharmacology. 128:1996;74-82
3. Aronson R., Offman H.J., Joffe R.T., Naylor D. Triiodothyronine augmentation in the treatment of refractory depression. A meta-analysis. Arch. Gen. Psychiatr. 53:1996;842-848
4. Bauer M., Whybrow P.C. Thyroid hormone, neural tissue and mood modulation. World J. Biol. Psychiatr. 2:2001;57-67
5. Bauer M., Heinz A., Whybrow P.C. Thyroid hormones, serotonin and mood: of synergy and significance in the adult brain. Mol. Psychiatr. 7:2002;140-156
6. 1A receptor agonist-induced corticotropin and cortisol responses after long-term ipsapirone and fluoxetine administration to healthy subjects. Clin. Pharmacol. Ther. 63:1998;428-436
7. Blier P., de Montigny C. Effect of chronic antidepressant treatment on the serotoninergic autoreceptor: a microiontophoretic study in rat. Naunyn-Schmiedeberg's Arch. Pharmacol. 314:1980;123-128
8. Blier P., de Montigny C. Current advances and trends in the treatment of depression. Trends Pharmacol. Sci. 15:1994;220-226
9. Blier P., de Montigny C. Possible serotonergic mechanisms underlying the antidepressant and anti-obsessive-compulsive disorder responses. Biol. Psychiatr. 44:1998;313-323
10. 1A receptors control 5-HT release in the rat medial prefrontal cortex. Neuroreport. 10:1999;1441-1445
11. Cleare A.J., McGregor A., O'Keane V. Neuroendocrine evidence for an association between hypothyroidism, reduced central 5-HT activity and depression. Clin. Endocrinol. 43:1995;713-719
12. Cleare A.J., McGregor A., Chambers S.M., Dawling S., O'Keane V. Thyroxine replacement increases central 5-hydroxytryptamine activity and reduces depressive symptoms in hypothyroidism. Neuroendocrinology. 64:1996;65-69
13. Dremencov E., Gur E., Lerer B., Newman M.E. Effects of chronic antidepressants and electroconvulsive shock on serotonergic neurotransmission in the rat hypothalamus. Prog. Neuropsychopharmacol. Biol. Psychiatr. 26:2002;1029-1034
14. Gur E., Lerer B., Newman M.E. Chronic clomipramine and triiodothyronine increase 5-HT levels in rat frontal cortex in vivo: relationship to 5-HT autoreceptor activity. J. Pharmacol. Exp. Ther. 288:1999;81-87
15. Gur E., Dremencov E., Van de Kar L.D., Lerer B., Newman M.E. Effects of chronically administered venlafaxine on 5-HT receptor activity in rat hippocampus and hypothalamus. Eur. J. Pharmacol. 436:2002a;57-65
16. 1B receptor activity in rat hippocampus and hypothalamus. Brain Res. 952:2002b;52-60
17. Gur E., Lifschytz T., Lerer B., Newman M.E. Effects of triiodothyronine and imipramine on basal 5-HT levels and 5-HT1 autoreceptor activity in rat cortex. Eur. J. Pharmacol. 457:2002c;37-43
18. 1A receptor-induced inhibition of 5-HT neuronal activity in the rat. Br. J. Pharmacol. 126:1999;1741-1750
19. 1A receptor function in brain following agonist or antidepressant administration. Life Sci. 72:2003;1665-1682
20. Kreiss D.S., Lucki I. Effects of acute and repeated administration of antidepressant drugs on extracellular levels of 5-HT measured in vivo. J. Pharmacol. Exp. Ther. 274:1995;866-876
21. 1A receptor function in normal subjects on clinical doses of fluoxetine: blunted temperature and hormone responses to ipsapirone challenge. Neuropsychopharmacology. 20:1999;628-639
22. 1A receptor responsivity in obsessive-compulsive disorder. Psychopharmacology. 105:1991;415-420
23. 1A agonist, 8-OH-DPAT, in male rats. Brain Res. 630:1993;148-156
24. 1A agonist, ipsapirone, by long-term treatment with fluoxetine, but not desipramine, in male rats. Biol. Psychiatr. 36:1994;300-308
25. 1A agonist. J. Pharmacol. Exp. Ther. 279:1996;1035-1042
26. 1A receptors. J. Pharmacol. Exp. Ther. 282:1997;1581-1590
27. 1A receptor control of dorsal raphe 5-HT neurones. Neuropharmacology. 41:2001;72-78
28. McKinley M.J., McAllen R.M., Mendelsohn F.A.O., Allen A.M., Chai S.Y., Oldfield B.J. Circumventricular organs: neuroendocrine interfaces between the brain and the hemal milieu. Front. Neuroendocrinol. 11:1990;91-127
29. Mezey E., Palkovits M. Meningeal relations of the rat hypothalamo-hypophyseal system. Extravascular fluid spaces in and around the median eminence. Brain Res. 250:1982;21-30
30. 1A receptors. J. Psychopharmacol. 16:2002;253-260
31. 2A receptors in adult rat brain. Neuropsychopharmacology. 24:2001;652-662
32. Nestler E.J., Barrot M., DiLeone R.J., Eisch A.J., Gold S.J., Monteggia L.M. Neurobiology of depression. Neuron. 34:2002;13-25
33. Newman M.E., Shapira B., Lerer B. Evaluation of central serotonergic function in affective and related disorders by the fenfluramine challenge test: a critical review. Int. J. Neuropsychopharmacol. 1:1998;49-69
34. 1A receptor sensitivity in rat hypothalamus and hippocampus. Neuropharmacology. 39:2000a;2309-2317
35. Newman M.E., Agid O., Gur E., Lerer B. Pharmacological mechanisms of T3 augmentation of antidepressant action. Int. J. Neuropsychopharmacol. 3:2000b;187-191
36. Pineyro G., Blier P. Autoregulation of serotonergic neurons: role in antidepressant drug action. Pharmacol. Rev. 51:1999;533-591
37. Prange A.J., Wilson I.C., Breese G.R., Lipton M.A. Hormonal alteration of imipramine reponse: a review. Sachar E.J. Hormones, Behaviour and Psychopathology. 1976;41 Raven Press, New York
38. 1A receptors: reductions in neuroendocrine responses to 8-OH-DPAT and in levels of Gz and Gi proteins. J. Pharmacol. Exp. Ther. 288:1999;98-106
39. Redei E.E., Solberg L.C., Kluczynski J.M., Pare W.P. Paradoxical hormonal and behavioral responses to hypothyroid and hyperthyroid states in the Wistar-Kyoto rat. Neuropsychopharmacology. 24:2001;632-639
40. Sandrini M., Vitale G., Vergoni A.V., Ottani A., Bertolini A. Effect of acute and chronic treatment with triiodothyronine on serotonin levels and serotonergic receptor subtypes in the rat brain. Life Sci. 58:1996;1551-1559
41. 1A receptor sensitivity. Psychopharmacology. 132:1997;296-302
42. 1B autoreceptor function in the anterior hypothalamus in vivo: effect of chronic antidepressant treatment. Br. J. Pharmacol. 126:1999;1777-1784
43. 2A receptor-mediated regulation of hippocampal BDNF mRNA expression. Neuropharmacology. 40:2001;48-56
44. Witherspoon L.R., El Shami A.S. Chemically blocked analog assays for free thyronines. Clin. Chem. 34:1988;9-16