Computational Challenges of Systems Biology

Computer

Volumn 37, Issue 5, 2004, Pages 26-33

  Finkelstein, Anthony ^a   Hetherington, James ^a   Li, Linzhong ^a   Margoninski, Ofer ^a   Saffrey, Peter ^a   Seymour, Rob ^a   Warner, Anne ^a  

^a University College   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COMPUTATIONAL METHODS; COMPUTER SCIENCE; MATHEMATICAL MODELS; MOLECULES;

BIOINFORMATICS; COMPUTER SCIENTISTS;

BIOLOGY;

EID: 3042678959     PISSN: 00189162     EISSN: None     Source Type: Journal    
DOI: 10.1109/MC.2004.1297236     Document Type: Article

References (12)

1. D. Noble, “Modeling the Heart: From Genes to Cells to the Whole Organ,” Science, vol. 295, 2002, pp. 1678-1682.
2. D. Noble and T. Colatsky, “A Return to Rational Drug Discovery: Computer-Based Models of Cells, Organs and Systems in Drug Target Identification,” Emerging Therapeutic Targets, vol. 4, 2000, pp. 39-49.
3. A. Hodgkin and A. Huxley, “A Quantitative Description of Membrane Current and Its Application to Conduction and Excitation in Nerve,” J. Physiology, vol. 117, 1952, pp. 500-544.
4. The Physiome Project, 2003; www.physiome.org.
5. M. Levin et al., “Origins of Individual Swimming Behavior in Bacteria,” Biophysical J., vol. 74, 1998, pp. 175-181.
6. C. Priami, ed., “Computational Methods in Systems Biology”, Proc. 1st Int'l Workshop Computational Methods in Systems Biology, Springer, 2003.
7. SBML: Systems Biology Markup Language, 2003; http://sbml.org/index.psp.
8. The Systems Biology Workbench, 2004; http://sbw.sourceforge.net.
9. CellML.org, 2001; www.cellml.org/public/about/what_is_cellml.html.
10. The UCL Beacon Project, 2003; http://grid.ucl.ac.uk/biobeacon/php/index.php.
11. C. Rosse and J. Mejino, “A Reference Ontology for Bioinformatics: The Foundational Model of Anatomy,” J. Biomedical Informatics, vol. 36, 2003, pp. 478-500.
12. Gene Ontology Consortium, Gene Ontology, 2004; www.geneontology.org.