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Volumn 66, Issue 1, 2004, Pages 11-13

Cyclic GMP and phosphodiesterase 5 inhibitor therapies: What's on the horizon

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC GMP; ILOPROST; NESIRITIDE; NITRATE; NITRIC OXIDE; PHOSPHODIESTERASE V INHIBITOR; SILDENAFIL; TADALAFIL; VARDENAFIL;

EID: 3042672838     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.104.001388     Document Type: Review
Times cited : (22)

References (11)
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    • Binding of tritiated sildenafil, tadalafil, vardenafil to the phosphodiesterase-5 catalytic site displays potency, specificity, heterogeneity, and cGMP stimulation
    • Blount MA, Beasley A, Zoraghi R, Sekhar KR, Bessay EP, Francis SH, and Corbin JD (2004) Binding of tritiated sildenafil, tadalafil, vardenafil to the phosphodiesterase-5 catalytic site displays potency, specificity, heterogeneity, and cGMP stimulation. Mol Pharmacol 66:144-152.
    • (2004) Mol Pharmacol , vol.66 , pp. 144-152
    • Blount, M.A.1    Beasley, A.2    Zoraghi, R.3    Sekhar, K.R.4    Bessay, E.P.5    Francis, S.H.6    Corbin, J.D.7
  • 3
    • 0242713126 scopus 로고    scopus 로고
    • Sildenafil in patients with cardiovascular disease
    • Brindis RG and Kloner RA (2003) Sildenafil in patients with cardiovascular disease. Am J Cardiol 92:26-36.
    • (2003) Am J Cardiol , vol.92 , pp. 26-36
    • Brindis, R.G.1    Kloner, R.A.2
  • 4
    • 0037195229 scopus 로고    scopus 로고
    • Erectile dysfunction: Comparison of efficacy and side effects of the PDE-5 inhibitors sildenafil, vardenafil and tadalafil: Review of the literature
    • Gresser U and Gleiter CH (2002) Erectile dysfunction: comparison of efficacy and side effects of the PDE-5 inhibitors sildenafil, vardenafil and tadalafil: review of the literature. Eur J Med Res 7:435-446.
    • (2002) Eur J Med Res , vol.7 , pp. 435-446
    • Gresser, U.1    Gleiter, C.H.2
  • 5
    • 1242298451 scopus 로고    scopus 로고
    • Sildenafil for pulmonary arterial hypertension: Still waiting for evidence
    • Humbert M and Simonneau G (2004) Sildenafil for pulmonary arterial hypertension: still waiting for evidence. Am J Respir Crit Care Med 169:6-7.
    • (2004) Am J Respir Crit Care Med , vol.169 , pp. 6-7
    • Humbert, M.1    Simonneau, G.2
  • 6
    • 0025081992 scopus 로고
    • NO and cyclic GMP formation upon electrical field stimulation causes relaxation of corpus cavernosum smooth muscle
    • Ignarro LJ, Bush GM, Buga KS, Wood KS, Fukuto JM, and Rajfer J (1990) NO and cyclic GMP formation upon electrical field stimulation causes relaxation of corpus cavernosum smooth muscle. Biochem Biophys Res Commun 170:843-850.
    • (1990) Biochem Biophys Res Commun , vol.170 , pp. 843-850
    • Ignarro, L.J.1    Bush, G.M.2    Buga, K.S.3    Wood, K.S.4    Fukuto, J.M.5    Rajfer, J.6
  • 7
    • 0348225320 scopus 로고    scopus 로고
    • The effect of sildenafil on oesophageal motor function in healthy subjects and patients with nutcracker oesophagus
    • Lee JI, Park H, Kim JH, Lee SI, and Conklin JL (2003) The effect of sildenafil on oesophageal motor function in healthy subjects and patients with nutcracker oesophagus. Neurogastrointest Motil 15:617-623.
    • (2003) Neurogastrointest Motil , vol.15 , pp. 617-623
    • Lee, J.I.1    Park, H.2    Kim, J.H.3    Lee, S.I.4    Conklin, J.L.5
  • 8
    • 0142200828 scopus 로고    scopus 로고
    • Effects of sildenafil on retinal blood flow and flicker-induced retinal vasodilatation in healthy subjects
    • Polak K, Wimpissinger B, Berisha F, Georgopoulos M, and Schmetterer L (2003) Effects of sildenafil on retinal blood flow and flicker-induced retinal vasodilatation in healthy subjects. Investig Ophthalmol Vis Sci 44:4872-4876.
    • (2003) Investig Ophthalmol Vis Sci , vol.44 , pp. 4872-4876
    • Polak, K.1    Wimpissinger, B.2    Berisha, F.3    Georgopoulos, M.4    Schmetterer, L.5
  • 9
    • 0038784879 scopus 로고    scopus 로고
    • Therapeutic potential of phosphodiesterase 5 inhibition for cardiovascular disease
    • Refflemann T and Kloner R (2003) Therapeutic potential of phosphodiesterase 5 inhibition for cardiovascular disease. Circulation 108:239-247.
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    • Refflemann, T.1    Kloner, R.2
  • 10
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    • Sildenafil improved pulmonary hypertension and peripheral blood flow in a patient with scleroderma-associated lung fibrosis and the Raynaud phenomenon
    • Rosenkranz S, Diet F, Karasch T, Weibrauch J, Wassermann K, and Erdmann E (2003) Sildenafil improved pulmonary hypertension and peripheral blood flow in a patient with scleroderma-associated lung fibrosis and the Raynaud phenomenon. Ann Intern Med 139:871-873.
    • (2003) Ann Intern Med , vol.139 , pp. 871-873
    • Rosenkranz, S.1    Diet, F.2    Karasch, T.3    Weibrauch, J.4    Wassermann, K.5    Erdmann, E.6
  • 11
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    • The evolving role of nesiritide in advanced or decompensated heart failure
    • Zinch I, Schofield RS, and Johnson JA (2003) The evolving role of nesiritide in advanced or decompensated heart failure. Pharmacotherapy 23:1266-1280.
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    • Zinch, I.1    Schofield, R.S.2    Johnson, J.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.