Centrally administered oxytocin elicits exaggerated grooming in oxytocin null mice

Pharmacology Biochemistry and Behavior

Volumn 78, Issue 2, 2004, Pages 333-339

  Amico, Janet A ^a,b   Vollmer, Regis R ^a   Karam, Joseph R ^a   Lee, Paul R ^c   Li, Xia ^a   Koenig, James I ^c   McCarthy, Margaret M ^c  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Grooming; Mice; Neurohypophysis; Oxytocin; Oxytocin receptor; Vasopressin

Indexed keywords

ARGIPRESSIN; ATOSIBAN; NEUROTRANSMITTER; OXYTOCIN; OXYTOCIN RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; AUTORADIOGRAPHY; CONTROLLED STUDY; GROOMING; MALE; MOUSE; NONHUMAN; NULL ALLELE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; STATISTICAL SIGNIFICANCE; WILD TYPE;

ANIMALS; GROOMING; INJECTIONS, INTRAVENTRICULAR; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OXYTOCIN;

ANIMALIA;

EID: 3042668046     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2004.04.006     Document Type: Article

References (30)

1. Amico J.A., Morris M., Vollmer R.R. Mice deficient in oxytocin manifest increased saline consumption following overnight fluid deprivation. Am. J. Physiol. Regul. Integr. Comp. Physiol. 281:2001;R1368-R1373
2. Amico J.A., Mantella R.C., Vollmer R.R. Consumption of solutions containing sodium chloride is enhanced in female oxytocin-deficient mice. Behav. Neurosci. 117:2003;32-37
3. Amico J.A., Mantella R.C., Vollmer R.R., Li X. Anxiety and stress responses in female oxytocin deficient mice. J. Neuroendocrinol. 16:2004;319-324
4. Bale T.L., Davis A.M., Auger A.P., Dorsa D.M., McCarthy M.M. CNS region-specific oxytocin receptor expression: importance in regulation of anxiety and sex behavior. J. Neurosci. 21:2001;2546-2552
5. Caldwell J.D., Drago F., Prange A.J. Jr., Pedersen C.A. A comparison of grooming behavior potencies of neurohypophysial nonapeptides. Regul. Pept. 14:1986;261-271
6. Delanoy R.L., Dunn A.J., Tintner R. Behavioral responses to intracerebroventricularly administered neurohypophysial peptides in mice. Horm. Behav. 11:1978;348-362
7. Drago F., Pedersen C.A., Caldwell J.D., Prange A.J. Oxytocin potently enhances novelty-induced grooming behavior in the rat. Brain Res. 368:1986;287-295
8. Drago F., Caldwell J.D., Pedersen C.A., Continella G., Scapagnini U., Prange A.J. Jr. Dopamine neurotransmission in the nucleus accumbens may be involved in oxytocin-enhanced grooming behavior of the rat. Pharmacol. Biochem. Behav. 24:1986;1185-1188
9. Drago F., Sarnyai Z., Dagata V. The inhibition of oxytocin-induced grooming by a specific receptor antagonist. Physiol. Behav. 50:1991;533-536
10. Drago F., Contarino A., Busa L. The expression of neuropeptide-induced excessive grooming behavior in dopamine D1 and D2 receptor-deficient mice. Eur. J. Pharmacol. 365:1999;125-131
11. Ferguson J.N., Young L.J., Hearn E.F., Matzuk M.M., Insel T.R. Social amnesia in mice lacking the oxytocin gene. Nat. Genet. 25:2000;284-288
12. Ferguson J.N., Aldag J.M., Insel T.R., Young L.J. Oxytocin in the medial amygdala is essential for social recognition in the mouse. J. Neurosci. 21:2001;8278-8285
13. Francis D.D., Young L.J., Meaney M.J., Insel T.R. Naturally occurring differences in maternal care are associated with the expression of oxytocin and vasopressin (V1A) receptors: gender differences. J. Neuroendocrinol. 15:2002;349-353
14. Gould B.R., Zingg H.H. Mapping oxytocin receptor gene expression in the mouse brain and mammary gland using an oxytocin receptor-LacZ reporter mouse. Neuroscience. 22:2003;155-167
15. Higuchi T., Honda K., Fukuoka T., Negoro H., Wakabayashi K. Release of oxytocin during suckling and parturition in the rat. J. Endocrinol. 105:1985;339-346
16. Kaltwasser M.T., Andres U. The interaction of central oxytocin and cholecystokinin regulates grooming behavior in the rat. Brain Res. 496:1989;380-384
17. Kaltwasser M.T., Crawley J.N. Oxytocin and cholecystokinin induce grooming behavior in the ventral tegmentum of the rat. Brain Res. 426:1987;1-7
18. Mantella R.C., Vollmer R.R., Li X., Amico J.A. Female oxytocin deficient mice display enhanced anxiety-related behavior. Endocrinology. 144:2003;2291-2296
19. Nishimori K., Young L.J., Guo Q., Wang Z., Insel T.R., Matzuk M.M. Oxytocin is required for nursing but is not essential for parturition or reproductive behavior. Proc. Natl. Acad. Sci. U. S. A. 93:1996;11699-11704
20. Neumann I.D. Involvement of the brain oxytocin system in stress coping: interactions with the hypothalamo-pituitary-adrenal axis. Prog. Brain Res. 139:2002;147-162
21. Pedersen C.A., Ascher J.A., Monroe Y.L., Prange A.J. Jr. Oxytocin induces maternal behavior in virgin female rats. Science. 216:1982;648-650
22. Puryear R., Rigatto K.V., Amico J.A., Morris M. Enhanced salt intake in oxytocin deficient mice. Exp. Neurol. 171:2001;323-328
23. Robinson D.A., Wei F., Wang G.D., Li P., Kim S.J., Vogt S.K., et al. Oxytocin mediates stress-induced analgesia in adult mice. J. Physiol. 540:2002;593-606
24. Stivers J.A., Kaltwasser M.T., Hill P.S., Hruby V.J., Crawley J.N. Ventral tegmental oxytocin induces grooming. Peptides. 9(Suppl. 1):1988;223-231
25. Van Erp A.M., Kruk M.R., Semple D.M., Verbeet D.W. Initiation of self-grooming in resting rats by local PVH infusion of oxytocin but not alpha-MSH. Brain Res. 607:1993;108-112
26. Verbalis J.G., Blackburn R.E., Olson B.R., Stricker E.M. Central oxytocin inhibition of food and salt ingestion: a mechanism for intake regulation of solute homeostasis. Regul. Pept. 45:1993;149-154
27. Windle R.J., Shanks N., Lightman S.L., Ingram C.D. Central oxytocin administration reduces stress-induced corticosterone release and anxiety behavior in rats. Endocrinology. 138:1997;2829-2834
28. Winslow J.T., Hearn E.F., Ferguson J., Young L.J., Matzuk M.M., Insel T.R. Infant vocalization, adult aggression, and fear behavior of an oxytocin null mutant mouse. Horm. Behav. 37:2000;145-155
29. Young W.S. III, Shepard E., Amico J., Hennighausen L., Wagner K.U., LaMarca M.E., et al. Deficiency in mouse oxytocin prevents milk ejection, but not fertility or parturition. J. Neuroendocrinol. 8:1996;847-853
30. Young L.J., Winslow J.T., Wang Z., Gingrich B., Guo Q., Matzuk M.M., et al. Gene targeting approaches to neuroendocrinology: oxytocin, maternal behavior, and affiliation. Horm. Behav. 31:1997;221-231