Ovarian hypercytolipidemia induced by obese (ob/ob) and diabetes (db/db) mutations: Basis of female reproductive tract involution II

Tissue and Cell

Volumn 36, Issue 3, 2004, Pages 157-169

  Garris, David R ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

Author keywords

Diabetes (db db) mutation; Diabetes obesity syndrome; Female reproductive tract; Hypercytolipidemia; Lipidemia; Lipidemic organ involution; Obese (ob ob) mutation; Ovarian follicular ultrastructure

Indexed keywords

ADIPOCYTE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL NUCLEUS; CELL ORGANELLE; CELL VACUOLE; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE GENITAL SYSTEM; FEMALE INFERTILITY; FEMALE STERILITY; GENE EXPRESSION; GENE MUTATION; GENOTYPE; GRANULOSA CELL; HYPERGLYCEMIA; HYPERTRIGLYCERIDEMIA; INTERSTITIUM; INVOLUTION; LIPIDOSIS; METABOLIC PARAMETERS; MOUSE; NONHUMAN; OBESITY; OVARY DISEASE; OVARY FOLLICLE CELL; THECA CELL; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE;

EID: 3042665931     PISSN: 00408166     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tice.2004.01.001     Document Type: Article

References (32)

1. Chieri, R.A., Pivetta, O.H., Foglia, V.G., 1969. Altered ovulation pattern in experimental diabetes. Fertil. Steril. 20, 661-668.
2. Coleman, D.L., 1978. Obese and diabetes: two mutant genes causing diabetes-obesity syndromes in mice. Diabetologia 14, 141-148.
3. Coleman, D.L., Leiter, E.H., Appleweig, N., 1984. Therapeutic effects of dehydroepiandrosterone metabolites in diabetes mutant mice (C57BL/KsJ-db/db). Endocrinology 115, 239-243.
4. Foreman, D., Kolettis, E., Garris, D.R., 1983. Diabetes prevents the normal responses of the ovary to FSH. Endocr. Res. 19, 187-205.
5. Garris, D.R., 1984. Effects of progressive hyperglycemia on ovarian structure and function in the spontaneously diabetic Chinese hamster. Anat. Rec. 210, 485-489.
6. Garris, D.R., 1985. Diabetes-associated alterations in uterine structure in the C57BL/KsJ mouse: relationship to changes in estradiol accumulation, circulating ovarian steroid levels and age. Anat. Rec. 211, 414-419.
7. Garris, D.R., 1987. Depressed progesterone accumulation by the brain and peripheral tissues of diabetic C57BL/KsJ mice: normalization by estrogen therapy. Horm. Res. 25, 37-48.
8. Garris, D.R., 1988a. Effects of diabetes on uterine condition, decidualization, vascularization and corpus luteum function in the pseudopregnant rat. Endocrinology 122, 665-672.
9. Garris, D.R., 1988b. Reproductive tract and pancreatic norepinephrine levels in pre- and overt-diabetic C57BL/KsJ mice: relationship to body weight, blood glucose, serum insulin and reproductive dysfunction. Proc. Soc. Exp. Biol. Med. 189, 79-83.
10. Garris, D.R., 1989a. Effects of estradiol and progesterone on diabetes-associated utero-ovarian atrophy in C57BL/KsJ (db/db) mutant mice. Anat. Rec. 225, 310-317.
11. Garris, D.R., 1989b. Morphometric analysis of obesity (ob/ob) and diabetes (db/db) Associated hypothalamic neuronal degeneration in C57BL/KsJ mice. Brain Res. 501, 162-170.
12. Garris, D.R., 1990. Effects of estradiol and progesterone on reproductive tract atrophy and tissue adrenergic indices in diabetic C57BL/KsJ mice. Proc. Soc. Exp. Biol. Med. 193, 39-45.
13. Garris, D.R., 2004. Ultrastructural analysis of progressive uterine hypercytolipidemia induced by obese (ob/ob) and diabetes (db/db) mutations: basis of female reproductive tract involution I. Tissue Cell 36, 19-28.
14. Garris, D.R., Coleman, D.L., Morgan, C.R., 1985. Age- and diabetes-related changes in tissue glucose uptake and estradiol accumulation in the C57BL/KsJ mouse. Diabetes 34, 47-52.
15. Garris, D.R., Garris, B.L., 2002. Lipotrophic diabetes-associated utero-ovarian dysfunction: influence of cellular lipid deposition on norepinephrine indices. Horm. Res. 58, 120-127.
16. Garris, D.R., Garris, B.L., 2003a. Diabetes-induced, progressive, endometrial involution: characterization of periluminal epithelial lipoatrophy. Diabetes 52, 51-58.
17. Garris, D.R., Garris, B.L., 2003b. Diabetes (db/db)-mutation induced ovarian involution: progressive hypercytolipidemia. Exp. Biol. Med. 228, 1040-1050.
18. Garris, D.R., Smith, C., Davis, D., Diani, A.R., Gerritsen, G., 1982. Morphometric analysis of the hypothalamic-ovarian axis of the ketonuric-diabetic Chinese hamster: relationship to reproductive cycle. Diabetologia 23, 275-279.
19. Garris, D.R., West, R.L., Pekala, P.H., 1986. Structural and metabolic changes associated with reproductive tract atrophy and adiposity in diabetic female mice. Anat. Rec. 216, 359-366.
20. Garris, D.R., Williams, S., Smith-West, C., West, L., 1984a. Diabetes-associated endometrial disruption in the Chinese hamster: structural changes in relation to progressive hyperglycemia. Gynecol. Obstet. Invest. 17, 293-300.
21. Garris, D.R., Whitehead, D.S., Morgan, C.R., 1984b. Effects of alloxan-induced diabetes on corpus luteum function in the pseudopregnant rat. Diabetes 33, 611-615.
22. Garris, D.R., Williams, S.K., West, L., 1985. Morphometric evaluation of the diabetes-associated ovarian atrophy in the C57BL/KsJ mouse: relationship to age and ovarian function. Anat. Rec. 211, 434-443.
23. Hall, R.E., Tillman, A.J.B., 1951. Diabetes and pregnancy. Am. J. Obstet. Gynecol. 61, 1107-1115.
24. Hoffman, E.O., Flores, T.R., Coover, J., Garrett, H.B., 1983. Polychrome stains for high resolution light microscopy. Lab. Med. 14, 779-781.
25. Johnson, L.M., Sidman, R.L., 1979. A reproductive endocrine profile in the diabetes (db) mutant mouse. Biol. Reprod. 20, 552-559.
26. Leibel, R.L., Chung, W.K., Chua Jr., S.C., 1997. The molecular genetics of rodent single gene obesities. J. Biol. Chem 272, 31937-31940.
27. Mounzih, K., Lu, R., Chehab, F.F., 1997. Leptin treatment rescues sterility of genetically obese ob/ob/males. Endocrinology 138, 1190-1193.
28. Qiu, J., Mounzih, K., Ewart-Toland, A., Chehab, F.F., 2001. Leptin-deficient mice backcrossed to the BALB/cj genetic background have reduced adiposity, enhanced fertility, normal body temperature and severe diabetes. Endocrinology 142, 3421-3425.
29. Santonge, J., Cote, R., 1983. Intrauterine growth retardation and diabetic pregnancy: two types of fetal malnutrition. Am. J. Obstet. Gynecol. 146, 194-201.
30. Shimabukuro, M., Zhou, Y.T., Levi, M., Unger, R.H., 1998. Fatty acid-induced B cell apoptosis: a link between obesity and diabetes. Proc. Natl. Acad. Sci. 95, 2498-2506.
31. Swerdloff, R.S., Batt, R.A., Bray, G.A., 1976. Reproductive hormonal function in the genetically obese (ob/ob) mouse. Endocrinology 98, 1359-1364.
32. Unger, R.H., Zhou, Y.T., 2001. Lipotoxicity of B-cells in obesity and in other causes of fatty acid spillover. Diabetes 50 (Suppl. 1), S118-S121.