Different effects of TMP and verapamil on nociception mediated by P2X 3 receptor activation of rat hindpaw

Chinese Pharmacological Bulletin

Volumn 20, Issue 4, 2004, Pages 476-478

  Liang, Shang Dong ^a   Teng, Li Li ^b   Gao, Yun ^a   Xu, Bao Hua ^a   Mu, Song Niu ^a   Xu, Chang Shui ^a  

^a JIANGXI MEDICAL COLLEGE   (China)

^b Gannan Normal College   (China)

Author keywords

ATP; Intraplantar drug administration; Intrathecal drug administration; Nociception; P2X receptors; Tetramethylpyrazine; Verapamil

Indexed keywords

PURINE P2 RECEPTOR; PURINE P2X3 RECEPTOR; TETRAMETHYLPYRAZINE; VERAPAMIL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; FOOT; NOCICEPTION; NONHUMAN; RAT;

EID: 3042628526     PISSN: 10011978     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Chen CC, Akoplan AN, Sivilotti L et al. A P2X purinoceptor expressed by a subset of sensory neurons. Nature, 1995; 377 (6548): 428-31
2. Bland-Ward PA, Humphrey PPA. Acute nociception mediated by hindpaw P2X receptor activation in the rat. Br J Pharmacol, 1997; 122(2): 366-71
3. Hamilton SG, Wade A, McMahon SB. The effects of inflammation and inflammatory mediators on nociceptive behavior induced by ATP analogues in the rat. Br J Pharmacol, 1999; 126 (1): 326-32
4. Hamilton SG, Warburton J, Bhattacharjee A et al. ATP in human skin elicits a dose-related pain response under conditions of hyperalgesia. Brain, 2000; 123(Pt 6): 1238-465
5. Ozaki Y. Antiinflammatory effect of tetramethylpyrazine and ferulic acid. Chem Pharm Bull, 1991; 40(4): 954-6
6. Driessen B, Reimann W, Selve N et al. Antinociceptive effect of intrathecally administered P2-purinoceptor antagonists in rats. Brain Res, 1994; 666(2): 182-8
7. Fredholm BB, Abbracchio MP, Burnstock G et al. Towards a revised nomenclature for P1 and P2 receptors. Tremds Pharmacol, 1997; 18(3): 79-82
8. Dunn PM, Zhong Y, Burnstock G. P2X receptors in peripheral neurons. Prog Neurobiol, 2001; 68(2): 107-34
9. Neugebauer V, Vangegas H, Nebe J et al. Effects of N-and L-type calcium channel antagonists on the responses of nociceptive spinal cord neurons to mechanical stimulation of the normal and the inflamed knee joint, J Neurophysiol, 1996; 76(6): 3740-9
10. Burnstock G. Purine-mediated signaling in pain and visceral perception. Trends Pharmacol Sci, 2001; 22(4): 182-8