Potential role of macrophages as immunoregulators of pregnancy

Reproductive Biology and Endocrinology

Volumn 1, Issue , 2003, Pages

  Mor, Gil ^a   Abrahams, Vikki M ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; CELL DEATH; CELL PROLIFERATION; CELL SURVIVAL; CYTOKINE PRODUCTION; DECIDUA; FEMALE; HISTOGENESIS; HUMAN; HUMAN CELL; IMMUNE SYSTEM; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; MACROPHAGE FUNCTION; MOTHER; NIDATION; PREGNANCY; REVIEW; TH1 CELL; TH2 CELL; TROPHOBLAST; FETOMATERNAL TRANSFUSION; IMMUNOLOGY; MACROPHAGE; PATHOLOGY; PHAGOCYTOSIS; PREGNANCY COMPLICATION;

APOPTOSIS; FEMALE; HUMANS; MACROPHAGES; MATERNAL-FETAL EXCHANGE; PHAGOCYTOSIS; PREGNANCY; PREGNANCY COMPLICATIONS;

EID: 3042625540     PISSN: 14777827     EISSN: None     Source Type: Journal    
DOI: 10.1186/1477-7827-1-119     Document Type: Review

References (55)

1. Mincheva-Nilsson L, Baranov V, Yeung M, Hammarstrom S, Hammarstrom ML: Immunomorphologica studies in human decidua-associated lymphoid cells in normal early pregnancy. J Immuno 1994, 152:2020-2032.
2. Lessin DL, Hunt JS, King CR, Wood GW: Antigen expression by cells near the maternal-fetal interface. Am J Reprod Immunol Microbiol 1988, 16:1-7.
3. Loke YW, King A: Immunology of implantation. Baillieres Best Pract Res Clin Obstet Gynaecol 2000, 14:827-837.
4. Moffett-King A: Natural killer cells and pregnancy. Nat Rev Immunol 2002, 2:656-663.
5. Kabawat SE, Mostoufi-Zadeh M, Driscoll SG, Bhan AK: Implantation site in normal pregnancy. A study with monoclonal antibodies. Am J Pathol 1985, 118:76-84.
6. Bulmer JN, Pace D, Ritson A: Immunoregulatory cells in human decidua: morphology, immunohistochemistry and function. Reprod Nutr Dev 1988, 28:1599-1613.
7. Uckan D, Steele A, Cherry, Wang BY, Chamizo W, Koutsonikolis A, Gilbert-Barness E, Good RA: Trophoblasts express Fas ligand: a proposed mechanism for immune privilege in placenta and maternal invasion. Mol Hum Reprod 1997, 3:655-662.
8. Khong TY: Immunohistologic study of the leukocytic infiltrate in maternal uterine tissues in normal and preeclamptic pregnancies at term. Am J Reprod Immunol Microbiol 1987, 15:1-8.
9. Simon C, Martin JC, Meseguer M, Caballero-Campo P, Valbuena D, Pellicer A: Embryonic regulation of endometrial molecules in human implantation. J Reprod Fertil Suppl 2000, 55:43-53.
10. Simon C, Moreno C, Remohi J, Pellicer A: Cytokines and embryo implantation. J Reprod Immunol 1998, 39:117-131.
11. Formby B: Immunologic response in pregnancy. Its role in endocrine disorders of pregnancy and influence on the course of maternal autoimmune diseases. Endocrinol Metab Clin North Am 1995, 24:187-205.
12. Wegmann TG, Lin H, Guilbert L, Mosmann TR: Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a TH2 phenomenon? Immunol Today 1993, 14:353-356.
13. Aschkenazi S, Naftolin F, Mor G: Menopause, Sex Hormones and the Immune System. Menopause Management 2000, 9:6-13.
14. Hanna N, Hanna I, Hleb M, Wagner E, Dougherty J, Balkundi D, Padbury J, Sharma S: Gestational age-dependent expression of IL-10 and its receptor in human placental tissues and isolated cytotrophoblasts. J Immunol 2000, 164:5721-5728.
15. Tranchot-Diallo J, Gras G, Parnet-Mathieu F, Benveniste O, Marce D, Roques P, Milliez J, Chaouat G, Dormont D: Modulations of cytokine expression in pregnant women. Am J Reprod Immunol 1997, 37:215-226.
16. von Rango U, Classen-Linke I, Raven G, Bocken F, Beier HM: Cytokine microenvironments in human first trimester decidua are dependent on trophoblast cells. Fertil Steril 2003, 79:1176-1186.
17. Bennett WA, Lagoo-Deenadayalan S, Stopple JA, Barber WH, Hale E, Brackin MN, Cowan BD: Cytokine expression by first-trimester human chorionic villi. Am J Reprod Immunol 1998, 40:309-318.
18. Casey ML, Cox SM, Beutler B, Milewich L, MacDonald PC: Cachectin/tumor necrosis factor-alpha formation in human decidua. Potential role of cytokines in infection-induced preterm labor. J Clin Invest 1989, 83:430-436.
19. Casey ML, Cox SM, Word RA, MacDonald PC: Cytokines and infection-induced preterm labour. Reprod Fertil Dev 1990, 2:499-509.
20. Yoon BH, Romero R, Yang SH, Jun JK, Kim IO, Choi JH, Syn HC: Interleukin-6 concentrations in umbilical cord plasma are elevated in neonates with white matter lesions associated with periventricular leukomalacia. Am J Obstet Gynecol 1996, 174:1433-1440.
21. Levy R, Smith SD, Yusuf K, Huettner PC, Kraus FT, Sadovsky Y, Nelson DM: Trophoblast apoptosis from pregnancies complicated by fetal growth restriction is associated with enhanced p53 expression. Am J Obstet Gynecol 2002, 186:1056-1061.
22. Ratts VS, Tao XJ, Webster CB, Swanson PE, Smith SD, Brownbill P, Krajewski S, Reed JC, Tilly JL, Nelson DM: Expression of BCL-2, BAX and BAK in the trophoblast layer of the term human placenta: a unique model of apoptosis within a syncytium. Placenta 2000, 21:361-366.
23. Smith SC, Baker PN, Symonds EM: Increased placental apoptosis in intrauterine growth restriction. Am J Obstet Gynecol 1997, 177:1395-1401.
24. Smith SC, Baker PN, Symonds EM: Placental apoptosis in normal human pregnancy. Am J Obstet Gynecol 1997, 177:57-65.
25. Allaire AD, Ballenger K, Wells SR, MCMahon MJ, Lessey BA: Placental apoptosis in preeclampsia. Obstetrics and Gynecoly 2000, 96:271-276.
26. Zhou Y, Damsky CH, Chiu K, Roberts JM, Fisher SJ: Preeclampsia is associated with abnormal expression of adhesion molecules by invasive cytotrophoblasts. J Clin Invest 1993, 91:950-960.
27. Graham CH, McCrae KR: Altered expression of gelatinase and surface-associated plasminogen activator activity by trophoblast cells isolated from placentas of preeclamptic patients. Am J Obstet Gynecol 1996, 175:555-562.
28. Hara N, Fujii T, Yamashita T, Kozuma S, Okai T, Taketani Y: Altered expression of human leukocyte antigen G (HLA-G) on extravillous trophoblasts in preeclampsia: immunohistological demonstration with anti-HLA-G specific antibody "87G" and anti-cytokeratin antibody "CAM5.2". Am J Reprod Immunol 1996, 36:349-358.
29. Reister F, Frank HG, Heyl W, Kosanke G, Huppertz B, Schroder W, Kaufmann P, Rath W: The distribution of macrophages in spiral arteries of the placental bed in pre-eclampsia differs from that in healthy patients. Placenta 1999, 20:229-233.
30. Fadok VA, Chimini G: The phagocytosis of apoptotic cells. Semin Immunol 2001, 13:365-372.
31. Savill J, Fadok V: Corpse clearance defines the meaning of cell death. Nature 2000, 407:784-788.
32. Piacentini M, Autuori F: Immunohistochemical localization of tissue transglutaminase and Bcl-2 in rat uterine tissues during embryo implantation and post-partum involution. Differentiation 1994, 57:51-61.
33. Duvall E, Wyllie AH, Morris RG: Macrophage recognition of cells undergoing programmed cell death (apoptosis). Immunology 1985, 56:351-358.
34. Mor G, Straszewski S, Kamsteeg M: The role of the Fas/FasL system in reproductive organs: Survival and apoptosis. Biochemical Pharmacology 2002, 64:1305-1315.
35. Voll RE, Herrmann M, Roth EA, Stach C, Kalden JR, Girkontaite I: Immunosuppressive effects of apoptotic cells. Nature 1997, 390:350-351.
36. Huynh ML, Fadok VA, Henson PM: Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-beta1 secretion and the resolution of inflammation. J Clin Invest 2002, 109:41-50.
37. Duffield JS, Ware CF, Ryffel B, Savill J: Suppression by apoptotic cells defines tumor necrosis factor-mediated induction of glomerular mesangial cell apoptosis by activated macrophages. Am J Pathol 2001, 159:1397-1404.
38. De M, Wood GW: Influence of Oestrogen and Progesterone on Macrophage Distribution in the Mouse Uterus. Journal of Endocrinology 1990, 126:417-424.
39. Miller L, Hunt J: Sex steroids hormones and macrophage function. Life Sciences 1996, 59:1-14.
40. Tachi C, Tachi S: Macrophages and implantation. Ann N Y Acad Sci 1986, 476:158-182.
41. Ben-Hur H, Gurevich P, Berman V, Tchanyshev R, Gurevich E, Zusman I: The secretory immune system as part of the placental barrier in the second trimester of pregnancy in humans. In Vivo 2001, 15:429-435.
42. Hunt JS: Cytokine networks in the uteroplacental unit: Macrophages as pivotal regulatory cells. Journal of Reproductive Immunology 1989, 16:1-17.
43. Garcia-Velasco J, Arici A, Naftolin F, Zreick T, Mor G: Macrophage-derived growth factors regulate FasL expression in endometrial stromal cells. Molecular Human Reproduction 1998, 5:642-650.
44. Mor G, Wei Y, Santen R, Gutierrez L, Eliza M, Lev B, Harada N, Wang J, Lysiak J, Diano S, Naftolin F: Macrophages, estrogen and the microenvironment of breast cancer. Journal of Steroid Biochemistry and Molecular Biology 1998, 67:403-411.
45. Mor G, Naftolin F: Oestrogen, menopause and the immune system. The Journal of the British Menopause Society 1998, 4:4-8.
46. Mor G, Sapi E, Abrahams VM, Rutherford T, Song J, Hao XY, Muzaffar S, Kohen F: Interaction of the Estrogen Receptors with the Fas Ligand Promoter in Human Monocytes. J Immunol 2003, 170:114-122.
47. Reiter I, Krammer B, Schwamberger G: Differential effect of apoptotic versus necrotic tumor cells on macrophage antitumor activities. J Immunol 1999, 163:1730-1732.
48. Cavaillon JM: Cytokines and macrophages. Biomed Pharmacother 1994, 48:445-453.
49. Pijnenborg R, McLaughlin PJ, Vercruysse L, Hanssens M, Johnson PM, Keith J. C., Jr., Van Assche FA: Immunolocalization of tumour necrosis factor-alpha (TNF-alpha) in the placental bed of normotensive and hypertensive human pregnancies. Placenta 1998, 19:231-239.
50. Kim YM, Chaiworapongsa T, Gomez R, Bujold E, Yoon BH, Rotmensch S, Thaler HT, Romero R: Failure of physiologic transformation of the spiral arteries in the placental bed in preterm premature rupture of membranes. Am J Obstet Gynecol 2002, 187:1137-1142.
51. Reister F, Frank HG, Kingdom JC, Heyl W, Kaufmann P, Rath W, Huppertz B: Macrophage-induced apoptosis limits endovascular trophoblast invasion in the uterine wall of preeclamptic women. Lab Invest 2001, 81:1143-1152.
52. Manfredi AA, Rovere P, Galati G, Heltai S, Bozzolo E, Soldini L, Davoust J, Balestrieri G, Tincani A, Sabbadini MG: Apoptotic cell clearance in systemic lupus erythematosus. I. Opsonization by antiphospholipid antibodies. Arthritis Rheum 1998, 41:205-214.
53. Guleria I, Pollard JW: The trophoblast is a component of the innate immune system during pregnancy. Nat Med 2000, 6:589-593.
54. Aschkenazi S, Straszewski S, Verwer KM, Foellmer H, Rutherford T, Mor G: Differential regulation and function of the Fas/Fas ligand system in human trophoblast cells. Biol Reprod 2002, 66:1853-1861.
55. Neale D, Demasio K, Illuzi J, Chaiworapongsa T, Romero R, Mor G: Maternal serum of women with pre-eclampsia reduces trophoblast cell viability: evidence for an increased sensitivity to Fas-mediated apoptosis. J Matern Fetal Neonatal Med 2003, 13:39-44.