Nitric oxide donors: Effects on fetoplacental blood flow

European Journal of Obstetrics and Gynecology and Reproductive Biology

Volumn 115, Issue 1, 2004, Pages 10-14

  Kähler, Chistiane ^a   Schleußner, Ekkehard ^a   Möller, Arne ^a   Seewald, Hans Joachim ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Doppler; Fetal blood flow; Nitric oxide

Indexed keywords

GLYCERYL TRINITRATE; NITRIC OXIDE DONOR; NITRODERM TTS 10;

ARTICLE; DOPPLER FLOWMETRY; DRUG EFFECT; FEMALE; FETUS BLOOD; HUMAN; HUMAN EXPERIMENT; MATHEMATICAL COMPUTING; MIDDLE CEREBRAL ARTERY; NORMAL HUMAN; PLACENTA CIRCULATION; PREGNANCY; PREMATURE LABOR; PRIORITY JOURNAL; RANK SUM TEST; STATISTICAL ANALYSIS; UMBILICAL ARTERY; UTERINE ARTERY;

EID: 3042606219     PISSN: 03012115     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-2115(02)00429-3     Document Type: Article

References (22)

1. Fox S.B., Khong T.Y. Lack of innervation of human umbilical cord. An immunohistological and histochemical study. Placenta. 11:1990;59-62
2. Myatt L., Brewer A., Brockman D.E. The action of nitric oxide in the perfused human fetal-placental circulation. Am. J. Obstet. Gynecol. 164:1991;687-692
3. Gude N.M., King R.G., Brennecke S.P. Role of endothelium-derived nitric oxide in maintenance of low fetal vascular resistance in placenta. Lancet. 336(8730):1990;1589-1590
4. Ignarro L.J., Buga G.M., Wood K.S., Byrns R.E., Chaudhuri G. Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proc. Natl. Acad. Sci. U.S.A. 84:1987;9265-9269
5. Moncada S., Higgs A. The L-arginine-nitric oxide pathway. N. Engl. J. Med. 329:1993;2002-2012
6. Paulick R.P., Meyers R.L., Rudolph A.M. Vascular responses of umbilical-placental circulation to vasodilators in fetal lambs. Am. J. Physiol. 261(1 Pt 2):1991;H9-14
7. Sladek S.M., Magness R.R., Conrad K.P. Nitric oxide and pregnancy. Am. J. Physiol. 272(Pt. 2):1997;R441-463
8. Hanretty K.P., Primrose M.H., Neilson J.P., Whittle M.J. Pregnancy screening by Doppler uteroplacental and umbilical artery waveforms. Br. J. Obstet. Gynaecol. 96:1989;1163-1167
9. Schleußner E., Richter S., groß W., Kähler C., Möller A., Möller U., et al. Glycery trinitrate patches versus fenoterol intravenous in tocolysis - a prospective randomised trial. Z. Geburtsh. Neonat. 205:2001;189-194
10. Kurmanavicius J., Florio I., Wisser J., Hebisch G., Zimmermann R., Muller R. Reference resistance indices of the umbilical, fetal middle cerebral and uterine arteries at 24-42 weeks of gestation. Ultrasound Obstet. Gynecol. 10:1997;112-120
11. Bogaert M.G. Clinical pharmacokinetics of glyceryl trinitrate following the use of systemic and topical preparations. Clin. Pharmacokinet. 12:1987;1-11
12. Luzi G., Caserta G., Iammarino G., Clerici G., DiRenzo G.C. Nitric oxide donors in pregnancy: fetomaternal hemodynamic effects induced in mild pre-eclamsia and threatened preterm labor. Ultrasound Obstet. Gynecol. 14:1999;101-109
13. Grunewald C., Kublickas M., Carlstrom K., Lunell N.O., Nisell H. Effects of nitroglycerin on the uterine and umbilical circulation in severe pre-eclampsia. Obstet. Gynecol. 86:1995;600-604
14. Cacciatore B., Halmesmaki E., Kaaja R., Teramo K., Ylikorkala O. Effects of transdermal nitroglycerin on impedance to flow in the uterine, umbilical, and fetal middle cerebral arteries in pregnancies complicated by pre-eclampsia and intrauterine growth retardation. Am. J. Obstet. Gynecol. 179:1998;140-145
15. Lees C., Valensise H., Black R., et al. The efficacy and fetal-maternal cardiovascular effects of transdermal glyceryl trinitrate in the prophylaxis of pre-eclampsia and its complications: a randomized double-blind placebo-controlled trial. Ultrasound Obstet. Gynecol. 12:1998;334-338
16. Makino Y., Izumi H., Makino I., Shirakawa K. The effect of nitric oxide on uterine and umbilical artery flow velocity waveform in pre-eclampsia. Eur. J. Obstet. Gynecol. Reprod. Biol. 73:1997;139-143
17. Izumi H., Makino Y., Shirakawa K., Garfield R.E. Role of nitric oxide on vasorelaxation in human umbilical artery. Am. J. Obstet. Gynecol. 172:1995;1477-1484
18. Chaudhuri G., Buga G.M., Gold M.E., Wood K.S., Ignarro L.J. Characterization and actions of human umbilical endothelium-derived relaxing factor. Br. J. Pharmacol. 102:1991;331-336
19. Di Iorio R., Marinoni E., Coacci F., LaTorre R., Cosmi E.V. Amniotic fluid nitric oxide and uteroplacental blood flow in pregnancy complicated by intrauterine growth retardation. Br. J. Obstet. Gynaecol. 104:1997;1134-1139
20. Beinder E., Mohaupt M.G., Schlembach D. Nitric oxide synthetase activity and Doppler parameters in the fetoplacental and uteroplacental circulation in pre-eclampsia. Hypertens. Pregnancy. 18:1999;115-127
21. Ramsay B., De Belder A., Campbell S., Moncada S., Martin J.F. A nitric oxide donor improves uterine artery diastolic blood flow in normal early pregnancy and in women at high risk of pre-eclampsia. Eur. J. Clin. Invest. 24:1994;76-78
22. Giles W., O'Callaghan S., Boura A., Walters W. Reduction in human fetal umbilical-placental vascular resistance by glyceryl trinitrate. Lancet. 340:1992;856. [Letter]