Further evidence that mammalian sex ratios at birth are partially controlled by parental hormone levels around the time of conception

Human Reproduction

Volumn 19, Issue 6, 2004, Pages 1250-1256

  James, William H ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Estrogen; Sex ratios; Testosterone

Indexed keywords

1,2 DIBROMO 3 CHLOROPROPANE; DIOXIN; GONADOTROPIN; SEX HORMONE; TESTOSTERONE;

ARTICLE; CHILDBIRTH; COITUS; CONCEPTION; CONGENITAL MALFORMATION; ENDOCRINE DISEASE; FEMALE; GONADOTROPIN BLOOD LEVEL; GYNECOLOGIC DISEASE; HISTOCOMPATIBILITY GENE; HORMONAL REGULATION; HORMONE BLOOD LEVEL; HUMAN; HYPOTHESIS; INTRAUTERINE INSEMINATION; LIPID DIET; MALE; MULTIPLE SCLEROSIS; NONHUMAN; OVULATION; PARASITOSIS; PREDICTION; PREGNANCY; PROGENY; RISK ASSESSMENT; RISK FACTOR; SEX DIFFERENCE; SEX DIFFERENTIATION; SEX RATIO; TERATOLOGY; TESTIS CANCER; TESTOSTERONE BLOOD LEVEL; VIRUS INFECTION;

MAMMALIA;

EID: 3042597271     PISSN: 02681161     EISSN: None     Source Type: Journal    
DOI: 10.1093/humrep/deh245     Document Type: Article

References (126)

1. Arena JFP and Smith DW (1978) Sex liability to single structural defects. Am J Dis Child 132,970-972.
2. Astolfi P, Cuccia M and Martinetti M (2001) Paternal HLA genotype and offspring sex ratio. Hum Biol 73,315-319.
3. Barnard CJ, Behnke JM, Gage AR, Brown H and Smithurst PR (1998) The role of parasite-induced immunodepression, rank and social environment in the modulation of behaviour and hormone concentration in male laboratory mice (Mus musculus). Proc R Soc B 265,693-701.
4. Bernstein ME (1954) Evidence of genetic variation of the primary sex ratio in man. J Hered 45,59-64.
5. Bernstein ME and Martinez-Gustin M (1961) Physical and psychological variation and the sex ratio. J Hered 52,109-112.
6. Bhopal RS, Tate JA, Foy C, Moffatt S and Phillimore PR (1999) Residential proximity to industry and adverse birth outcomes. Lancet 354,920-921.
7. Brown GR and Silk JB (2002) Reconsidering the null hypothesis: is maternal rank associated with birth sex ratios in primate groups? Proc Natl Acad Sci USA 99,11252-11255.
8. Bunger L, Wallace H, Bishop JO, Hastings IM and Hill WG (1998) Effects of thyroid hormone deficiency on mice selected for increased and decreased body weight and fatness. Genet Res 72,39-53.
9. Burnham TC, Chapman JF, Gray PB, McIntyre MH, Lipson SF and Ellison PT (2003) Men in committed romantic relationships have lower testosterone. Horm Behav 44,119-127.
10. Chahnazarian A, Blumberg BS and London WT (1988) Hepatitis B and the sex ratio at birth: a comparative analysis of four populations. J Biosoc Sci 20,357-70
11. Clark MM and Galef BG (1994) Reply. Nature 367, 328.
12. Clark, MM, Karpiuk P and Galef BG (1993) Hormonally mediated inheritance of acquired characteristics in Mongolian gerbils. Nature 364,712.
13. Clutton-Brock TH and Iason GR (1986) Sex ratio variation in mammals. Q Rev Biol 61,339-374.
14. Curtsinger JW, Ito R and Hiraizumi Y (1983) A two-generation study of human sex ratio variation. Am J Hum Genet 35, 951-961.
15. delRioGomez I, Marshall T, Tsai PP, Shao Y-S and Guo YL (2002) Number of boys born to men exposed to polychlorinated biphenyls. Lancet 360,143-144.
16. Dickinson H and Parker L (1994) Do alcohol and lead change the sex ratio? J Theor Biol 169,313.
17. Divon MY, Ferber A, Nisell H and Westgren M (2002) Male gender predisposes to prolongation of pregnancy. Am J Obstet Gynecol 187,1081-1083.
18. Dorgan JF, Hunsberger SA, McMahon RP, Kwiterovich PO, Lauer RM, Van Horn L et al. (2003) Diet and sex hormones in girls: findings from a randomized controlled clinical trial. J Natl Cancer Inst 95,132-141.
19. Edwards AWF (1960) The meaning of binomial distribution. Nature 186,1074.
20. Egeland GM, Sweeney MH, Fingerhut MA, Wille KK, Schnorr TM and Halperin WE (1994) Total serum testosterone and gonadotropins in workers exposed to dioxins. Am J Epidemiol 139,272-281.
21. Ehman KD and Scott ME (2002) Female mice mate preferentially with non-parasitized males. Parasitology 125,461-466.
22. Ellis L (1986) Evidence of neuroandrogenic etiology of sex roles from a combined analysis of human, nonhuman primate and nonprimate mammalian studies. Personality Individual Diff 7, 519-552.
23. Fertmann R Schumann M, Karmaus W, Schmid-Hopner S and Kuppers-Chinnow M (1997) Sex ratio variation in the Bille settlement. Scand J Work Environ Health 23,308-310.
24. Fukuda M, Fukuda K, Andersen CY and Byskov AG (2000) Right-sided ovulation favours pregnancy more than left-sided ovulation. Hum Reprod 15,1921-1926.
25. Garry VF, Harkins ME, Erickson LL, Long-Simpson LK, Holland SE and Burroughs BL (2002a) Birth defects, season of conception and sex of children born to pesticide applicators living in the Red River Valley of Minnesota, USA. Environ Health Perspect 110, Suppl 3,441-449.
26. Garry VF, Harkins M, Lyubimov A, Erickson L and Long L (2002b) Reproductive outcomes in the women of Red River Valley of the north. 1. The spouses of pesticide applicators: pregnancy loss, age at menarche and exposure to pesticides. J Toxicol Environ Health A, 65,769-786.
27. Garry VF, Holland SE, Erickson LL and Burroughs BL (2003) Male reproductive hormones and thyroid function in pesticide applicators in the Red River Valley of Minnesota. J Toxicol Environ Health A, 66,965-986.
28. Goerres HP and Gerbert K (1976) Sex ratio in offspring of pilots: a contribution to stress research. Aviat Space Environ Med 47,889-892.
29. Grajewski B, Cox C, Schrader SM, Murray WE, Edwards RM, Turner TW et al. (2000) Semen quality and hormone levels among radiofrequency heater operators. J Occup Environ Med 42, 239-250.
30. Grant VJ (1998) Maternal Personality, Evolution and the Sex Ratio. Do Mothers Control the Sex of the Infant? London, Routledge.
31. Harris JA, Rushton JP, Hampson E et al. (1996) Salivary testosterone and self-report aggressive and pro-social personality characteristics in men and women. Aggressive Behav 22,321-331.
32. Harris JA, Vernon PA and Boomsma DI (1998) The heritability of testosterone: a study of Dutch adolescent twins and their parents. Behav Genet 28,165-171.
33. Hastings IM and Hill WG (1997) The effect of testosterone in mice divergently selected on fat content on body weight. Genet Res 70,135-141.
34. Hillgarth N and Wingfield JC (1997) Parasite-mediated sexual selection: endocrine aspects. In Clayton DH and Moore J (eds), Host-Parasite Evolution. Oxford University Press, New York, pp. 78-104.
35. Hohenboken WD, Wagner CR and Blodgett DJ (1998) Inbreeding and reproduction in mice divergently selected for response to a dietary toxin. Theriogenology 49,1397-1407.
36. Jacobsen R, Bostofte E, Engholm G, Hansen J, Skakkebaek NE and Moller H (2000) Fertility and offspring sex ratio of men who develop testicular cancer: a record linkage study. Hum Reprod 15,1958-1961.
37. James WH (1980) Gonadotrophin and the human secondary sex ratio. Br Med J 281,711-712.
38. James WH (1989) Parental hormone levels and mammalian sex ratios at birth. J Theor Biol 139,59-67.
39. James WH (1991) Sex ratios and hormones in HLA related rheumatic diseases. Ann Rheum Dis 50, 401-404.
40. James WH (1992) The hypothesized hormonal control of mammalian sex ratio at birth - a second update. J Theor Biol 155,121-128.
41. James WH (1994a) Cycle day of insemination, sex ratio and duration of gestation. Ann Hum Biol 21,263-266.
42. James WH (1994b) Sex ratios of the offspring of patients with multiple sclerosis. Neuroepidemiology 13,216-219.
43. James WH (1995a) What stabilizes the sex ratio? Ann Hum Genet 59,243-249.
44. James WH (1995b) Sex ratios of offspring and the causes of placental pathology. Hum Reprod 10,1403-1406.
45. James WH (1995c) Re: 'Total serum testosterone and gonadotropins in workers exposed to dioxin'. Am J Epidemiol 141,476-477.
46. James WH (1996) Evidence that mammalian sex ratios at birth are partially controlled by parental hormone levels at the time of conception. J Theor Biol 180,271-286.
47. James WH (1997a) A potential mechanism for sex ratio variation in mammals. J Theor Biol 189,253-255.
48. James WH (1997b) The sex ratios of offspring of people exposed to nonionising radiation. Occup Environ Med 54,622-623.
49. James WH (1998) Hypothesis: one cause of polydactyly. J Theor Biol 192,1-2.
50. James WH (1999) Is transposition of the great arteries a consequence of maternal hormone imbalance? Evidence from the sex ratios of the relatives of probands. J Theor Biol 198,301-303.
51. James WH (2000a) Analysing data on the sex ratio of human births by cycle day of conception. Hum Reprod 15,1206-1207.
52. James WH (2000b) The sex ratio of children born to women with dermatoses of pregnancy. Br J Dermatol 143,1345.
53. James WH (2000c) Are oral clefts a consequence of maternal hormone imbalance? Evidence from the sex ratios of sibs of probands. Teratology 62,342-345.
54. James WH (2001a) The associated offspring sex ratios and cause(s) of hyperemesis gravidarum. Acta Obstet Gynecol Scand 80,378-379.
55. James WH (2001b) The sex ratio of births associated with placenta praevia. J Obstet Gynecol 21,160-161.
56. James WH (2001c) Finger length ratios, sexual orientation and offspring sex ratios. J Theor Biol 212,273-274.
57. James WH (2002a) Is male sex an independent risk factor for preterm birth? Am J Obstet Gynecol 186,594.
58. James WH (2002b) Sex ratios of affected and unaffected offspring of male and female patients with multiple sclerosis. Neuroepidemiology 21,207.
59. James WH (2002c) Hormone levels in pre-eclampsia. Acta Obstet Gynecol Scand 81,1152.
60. James WH (2002d) The light thrown on the causes of fatty liver of pregnancy by the sex ratio of associated offspring. J Obstet Gynecol 22,9-10.
61. James WH (2002e) Fish eaters and sex ratio. J Occup Environ Med 44,885.
62. James WH (2003) The causes of the excess males among preterm births and among postterm births. Hum Reprod 18,655-656.
63. James WH (2004a) A possible cause of pyloric stenosis. Birth Defects Res 'A': Clin Mol Teratol 70,37-39.
64. James WH (2004b) Hypotheses on how selective breeding for some traits in rodents may occasion correlated variation in offspring sex ratio. J Theor Biol, in press.
65. Jilma B, Eichler HG, Koppl C, Weber B, Pidlich JP, Ferenci P and Muller C (1998) Effects of testosterone suppression in serum levels of hepatitis B surface antigen and HBV-DNA in men. Liver 18,162-165.
66. Jimenez A, Fernandez R, Madrid BN, Morena PN, Borque C, Pintado B and Gutierrez AA (2003) Experimental demonstration that pre- and post-conceptional mechanisms influence sex ratio in mouse embryos. Mol Reprod Dev 66,162-165.
67. Karmaus W, Huang S and Cameron L (2002) Parental concentration of dichlorodiphenyl dichloroethene and polychlorinated biphenyls in Michigan fish eaters and sex ratio in offspring. J Occup Environ Med 44,8-13.
68. Kemper TD (1990) Social Structure and Testosterone. Rutgers University Press, London, p. 137.
69. King AC, Emco AL and Parsons OA (1995) Eysenck's personality dimensions and sex steroids in male abstinent alcoholics and nonalcoholics: an exploratory study. Biol Psychol 39,103-113.
70. King HD (1918) Studies on inbreeding. 3. The effect of inbreeding with selection on the sex ratio of the albino rat. J Exp Zool 27,1-35.
71. Kozlov MV (1999) Offspring sex ratio in a heavily polluted town. Reprod Toxicol 13,567-568.
72. Krackow S, Schmidt TA and Elepfandt A (2003) Sexual growth dimorphism affects birth sex ratio in house mice. Proc R Soc B 270,943-947.
73. Lazarus J (2002) Human sex ratios: adaptations and mechanisms, problems and prospects. In Hardy ICW (ed.), Sex Ratios: Concepts and Research Methods. Cambridge University Press, pp. 287-311.
74. Little BB, Rigsby CH and Little LR (1987) Pilot and astronaut offspring: possible G-force effects on human sex ratio. Aviat Space Environ Med 58,707-709.
75. Lloyd OL, Smith G, Lloyd MM, Holland Y and Gailey F (1985) Raised mortality from lung cancer and high sex ratios of births associated with industrial pollution. Br J Indust Med 42,475-480.
76. Lubinsky MS (1997) Classifying sex-biased congenital anomalies. Am J Med Genet 69,225-228.
77. Lyster WR (1981) Pollution and sex ratio of births. Med J Aust ii, 151-152.
78. Lyster WR ( 1982) Altered sex ratio in children of divers. Lancet ii, 152.
79. Manning JT (2002) Digit Ratio: A Pointer to Fertility, Behavior and Health. Rutgers University Press, London.
80. Manning JT, Martin S, Trivers RL et al. (2002) 2nd to 4th digit ratio and offspring Sex ratio. J Theor Biol 217,93-96.
81. Mantzoros CS, Georgiadis EI and Trichopoulos D (1995) Contribution of dihydrotestosterone to male sexual behaviour. Br Med J 310,1289-1291.
82. Mazzur S and Watson TM (1974) Excess males among sibs of Australian antigen carriers. Nature 250,60-61.
83. Meikle A, Stephenson R, Lewis C and Middleton R (1997) Age, genetic and non-genetic factors influencing variation in serum sex steroids and zonal volumes of the prostate and benign prostatic hyperplasia in twins. Prostate 33,105-111.
84. Mocarelli P, Gerthoux PM, Ferrari E, Patterson DG, Kieszak SM, Brambilla P et al. (2000) Paternal concentrations of dioxin and sex ratio of offspring. Lancet 355,1858-1863.
85. Moles A, Rizzi R and D'Amato FR (2003) The number of male pups within a litter of NMRI mice is associated with the dam's food preferences in late pregnancy. Psychoneuroendocrinology 28,250-260.
86. Moller H (1998) Trends in sex ratio, testicular cancer and male reproductive hazards: are they connected? Acta Pathol Microbiol Scand 106,232-239.
87. Morris NM, Udry JR, Khan-Dawood F et al (1987) Marital sex frequency and midcycle female testosterone. Arch Sex Behav 16,27-37.
88. Moshammer H and Neuberger M (2000) Sex ratio in the children of the Austrian chloracne cohort. Lancet 356,1271-1272.
89. Neave N and Wolfson S (2003) Testosterone, territoriality and the 'home advantage'. Physiol Behav 78,269-275.
90. Nunez JL and Juraska JM (1998) The size of the splenium of the rat corpus callosum: influence of hormones, sex ratios and neonatal cryoanesthesia. Dev Psychobiol 33,295-303.
91. Ollier W, Spector T, Silman A et al. (1989) Are certain HLA haplotypes responsible for low testosterone, levels in males? Dis Markers 7,139-143.
92. Ortiz RM, Wade CE and Morey-Holton E (2000) Urinary excretion of LH and testosterone from male rats during exposure to increased gravity: post spaceflight and centrifugation. Proc Soc Exp Biol Med 225,98-102.
93. Petersen PM, Skakkebaek NE, Vistisen K, Rorth M and Giwercman A (1999) Semen quality and reproductive hormones in men with testicular cancer. J Clin Oncol 17,941-947.
94. Piazze J, Nigro G., Mazzocco M, Marchiani E, Brancato V, Anceschi MM and Cosmi EV (1999) The effect of primary cytomegalovirus infection on fetal lum, maturity indices. Early Hum Dev 54,137-144.
95. Potashnik G and Yanai-Inbar I (1987) Dibromochloropropane (DBCP): an 8-year re-evaluation of testicular function and reproductive performance. Fertil Steril 47,317-323.
96. Reder AT, Makowiec RL and Lowy MT (1994) Adrenal size is increased in multiple sclerosis. Arch Neurol 51,151-154.
97. Richiardi L, Akre O, Montgomery SM, Lambe M, Kvist U and Ekbom A (2004) Fecundity and twinning rates as measures of fertility before diagnosis of germ cell testicular cancer. J Natl Cancer Inst 96,145-147.
98. Roberts AM (1978) The origins of fluctuations in the human secondary sex ratio. J Biosoc Sci 10,169-182.
99. Rockert HOE (1977) Changes in the vascular bed in testes of rats exposed to air at 6 atmospheres absolute pressure. IRCS J Med Sci 5,107.
100. Rockert HOE and Haglid K (1983) Reversible changes in the rate of DNA synthesis in the testes of rats after daily exposure to a hyperbaric environment of air. IRCS J Med Sci 11,531.
101. Rockert HOE, Damber J-E and Janson PO (1978) Testicular blood flow and plasma testosterone concentrations in anesthetized rats previously exposed to air at 6 ATA. Undersea Biomed Res 5,355-361.
102. Rosenfeld CS, Grimm KM, Livingston KA, Brokman AM, Lamberson WE and Roberts RM (2003) Striking variation in the sex ratio of pups born to mice according to whether maternal diet is high in fat or carbohydrate. Proc Natl Acad Sci USA 100,4628-4632.
103. Ryan BC and Vandenbergh JG (2002) Intrauterine position effects. Neurosci Biobehav Rev 26,665-678.
104. Ryan JJ, Amirova Z and Carrier G (2002) Sex ratios of children of Russian pesticide workers. Environ Health Perspect 110,A699-A701.
105. Saadat M, Ansari-Lari M and Bahaoddini A (2002) Sex ratio at birth in Masjid-I-Sulaiman (Khozestan Province, Iran). Occup Environ Med 59,853.
106. Schnorr TM, Lawson CC, Whelan EA et al (2001) Spontaneous abortion, sex ratio and paternal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Environ Health Perspect 109,1127-1132.
107. Schoner. (1927) Besteht eine Beziehung zwischen dem Geschlechte und der Seite des Corpus-luteum-Sitzes? Schweiz Med Woch, Basel 8,953-954.
108. Seeman MV (1996) The role of estrogen in schizophrenia. J Psychiatry Neurosci 21,123-127.
109. Sharp D (2003) Faster, higher, stronger... and deeper? Lancet 362,846.
110. Shields MD, O'Hare B, Nelson J, Stewart MC and Coyle P (2002) Maternal cytomegalovirus seropositivity. Br Med J 325,335.
111. Snyder RG (1961) The sex ratio of offspring of pilots of high performance military aircraft. Hum Biol 33,1-10.
112. Speir E, Yu ZX, Takeda K, Ferrans VJ and Cannon RO (2000) Antioxidant effect of estrogen on cytomegalovirus-induced gene expression in coronary artery smooth cells. Circulation 102,2990-2996.
113. Strollo F (1999) Hormonal changes in humans during spaceflight. Adv Space Biol Med 7,99-129.
114. Strollo F, Riondiono G, Harris B et al. (1998) The effect of microgravity on testicular androgen secretion. Aviat Space Environ Med 69,133-136.
115. Trichopoulos D (1967) Evidence of genetic variation in the human sex ratio. Hum Biol 39,170-175.
116. Trivers RL and Willard DE (1973) Natural selection of parental ability to vary the sex ratio of offspring. Science 179,90-91.
117. Vandenbergh JG and Huggett CL (1994) Mother's prior intrauterine position affects the sex ratio of her offspring in house mice. Proc Natl Acad Sci USA 91,11055-11059.
118. Vassilev ZP, Robson MG and Klotz JB (2001) Outdoor exposure to airborne polycyclic organic matter and adverse reproductive oucomes: a pilot study. Am J Ind Med 40,255-262.
119. Weir JA (1955) Male influence on sex ratio of offspring in high and low blood-pH. J Hered 46,277-283.
120. Wells R (1990) Human Sex Determination: An Historical Review and Synthesis. Riverlea Press, Tharwa, ACT Australia.
121. Whelan EM (1977) Boy or Girl? The Sex Selection Technique That Makes All Others Obsolete. Bobbs-Merrill, New York.
122. Whorton D, Milby TH, Krauss RM and Stubbs HA (1979) Testicular function in DBCP exposed workers. J Occup Med 21,161-166.
123. Williams FLR, Lawson AB and Lloyd OL (1992) Low sex ratios of births in areas at risk from air pollution from incinerators as shown by geographical analysis and 3-dimensional mapping. Int J Epidemiol 21,311-319.
124. Williams FLR, Ogston SA and Lloyd OL (1995) Sex ratios of births, mortality and air pollution: can measuring the sex ratios of births help to identify health hazards from air pollution in industrial environments? Occup Environ Med 52,164-169.
125. Wilson SP, Goodale WD, Kyle WH and Godfrey EE (1971) Long term selection for body weight in mice. J Hered 62,228-234.
126. Zuckerman M (1994) Behavioral Expressions and Biosocial Bases of Sensation Seeking. Cambridge University Press, New York.