Drugs pharmacokinetics in ICU patients: Consequences of hypoalbuminemia upon drugs monitoring and dosing scheme [5]

Intensive Care Medicine

Volumn 30, Issue 6, 2004, Pages 1247-

  Lagneau, Franck ^a   Perbet, Sébastien ^a   Delefosse, Didier ^a   Wernet, Anne ^a   Stocco, Jeanick ^a   Marty, Jean ^a  

^a BEAUJON HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

LEUCINE; VALPROIC ACID;

AGITATION; ARTIFICIAL VENTILATION; BLOOD LEVEL; HEMODIALYSIS; HUMAN; LETTER; LIVER TRANSPLANTATION; MAPLE SYRUP URINE DISEASE; NEUROTOXICITY; PROTEIN DIET; SEDATION;

ADULT; ANTICONVULSANTS; HUMANS; HYPOALBUMINEMIA; VALPROIC ACID;

EID: 3042591772     PISSN: 03424642     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00134-004-2313-6     Document Type: Letter

References (5)

1. Consensus conference (1996) Use of albumin solutions in surgical anesthesia and surgical intensive care of adults. Ann Fr Anesth Reanim 15:407-568
2. Bertucci C, Domenici E (2002) Reversible and covalent binding of drugs to human serum albumin: methodological approaches and physiological relevance. Curr Med Chem 9:1463-1481
3. Nellis MM, Kasinski A, Carlson M, Allen R, Schaefer AM, Schwartz EM, Danner DJ (2003) Relationship of causative genetic mutations in maple syrup urine disease with their clinical expression. Mol Genet Metab 80:189-195
4. Chadwick D (1985) Concentration-effect relationships of valproic acid. Clin Pharmakcokinet 10:155-163
5. Bellver G, Sanchez G, Gonzalez A, Buelga S, Gil D (1993) Plasma protein binding kinetics of valproic acid over broad dosage range: therapeutic implications. J Clin Pharm Res 18:191-197