"Cyst-like" structures within the ciliary shafts in children with bronchiectasis

European Respiratory Journal

Volumn 23, Issue 6, 2004, Pages 857-860

  Pifferi, M ^a   Cangiotti, A M ^b   Caramella, D ^a   Pietrobelli, A ^c   Ragazzo, V ^a   De Marco, E ^a   Macchia, P ^a   Cinti, S ^b   Boner, A L ^c  

^a UNIVERSITY OF PISA   (Italy)

^b UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^c UNIVERSITY OF VERONA   (Italy)

Author keywords

Bronchiectasis children; Cyst like structures; High resolution computed tomography; Transmission electron microscopy

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; BRONCHIECTASIS; CHILD; CILIARY DYSKINESIA; CILIARY MOTILITY; CLINICAL ARTICLE; CORRELATION ANALYSIS; DISEASE SEVERITY; FEMALE; FOLLOW UP; HIGH RESOLUTION COMPUTER TOMOGRAPHY; HUMAN; INFANT; LOWER RESPIRATORY TRACT INFECTION; MALE; MEDICAL ASSESSMENT; NASAL BIOPSY; PREVALENCE; PRIORITY JOURNAL; RESPIRATORY TRACT INFLAMMATION; THORAX RADIOGRAPHY; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE;

EID: 3042589351     PISSN: 09031936     EISSN: None     Source Type: Journal    
DOI: 10.1183/09031936.04.00085704     Document Type: Article

References (24)

1. Afzelius BA. A human syndrome caused by immotile cilia. Science 1976; 193: 317-319.
2. Schidlow DV. Primary ciliary dyskinesia (the immotile cilia syndrome). Ann Allergy 1994; 73: 457-469.
3. Bush A, Cole P, Hariri M, et al. Primary ciliary dyskinesia: diagnosis and standards of care. Eur Respir J 1998; 12: 982-988.
4. Afzelius BA. Immotile cilia syndrome: past, present, and prospects for the future. Thorax 1998; 53: 894-897.
5. Pasteur MC, Helliwell SM, Houghton SJ, et al. An investigation into causative factors in patients with bronchiectasis. Am J Respir Crit Care Med 2000; 162: 1277-1284.
6. Greenstone M, Rutman A, Pavia D, Lawrence D, Cole PJ. Normal axonemal structure and function in Kartagener's syndrome: an explicable paradox. Thorax 1985; 40: 956-957.
7. Pifferi M, Cangiotti AM, Ragazzo V, Baldini G, Cinti S, Boner AL. Primary ciliary dyskinesia: diagnosis in children with inconclusive ultrastructural evaluation. Pediatr Allergy Immunol 2001; 12: 274-282.
8. Tsang KWT, Tipoe G, Sun J, et al. Severe bronchiectasis in patients with "cystlike" structures within the ciliary shafts. Am J Respir Crit Care Med 2000; 161: 1300-1305.
9. McGuinness G, Naidich DP, Leitman BS, McCauley DI. Bronchiectasis: CT evaluation. Am J Roentgenol 1993; 160: 253-259.
10. Rutland J, Cole PJ. Non-invasive sampling of nasal cilia for measurement of beat frequency and study of ultrastructure. Lancet 1980; 2: 564-565.
11. Braga PC. A variable-thickness, multipurpose culture chamber for high-magnification observation. J Microscopy 1990; 159: 285-288.
12. Rossman CM, Forrest JB, Lee RMKW, Newhouse MT. The dyskinetic cilia syndrome. Ciliary motility in immotile cilia syndrome. Chest 1980; 78: 580-582.
13. Carlén B, Stenram U. Ultrastructural diagnosis in the immotile cilia syndrome. Ultrastruct Pathol 1987; 11: 653-658.
14. Rossman CM, Lee RMKW, Forrest JB, Newhouse MT. Nasal ciliary ultrastructure and function in patient with primary ciliary dyskinesia compared with that in normal subjects and in subjects with various respiratory diseases. Am Rev Respir Dis 1984; 129: 161-167.
15. Wilson R. Secondary ciliary dysfunction. Clin Sci 1988; 75: 113-120.
16. Buchdahl RM, Reiser J, Ingram D, Rutman A, Cole PJ, Warner JO. Ciliary abnormalities in respiratory disease. Arch Dis Child 1988; 63: 238-243.
17. Lurie M, Rennert G, Goldenberg S, Rivlin J, Greenberg E, Katz I. Ciliary ultrastructure in primary ciliary dyskinesia and other chronic respiratory conditions: the relevance of microtubular abnormalities. Ultrastruct Pathol 1992; 16: 547-553.
18. Fonzi L, Lungarella G, De Santi MM. Ultrastructural observations on morphogenesis of atypical cilia. Anat Anz Jena 1982; 151: 151-159.
19. Hagiwara H, Ohwada N, Aoki T, Takata K. Ciliogenesis and ciliary abnormalities. Med Electron Microsc 2000; 33: 109-114.
20. Afzelius BA. "Immotile cilia" syndrome and ciliary abnormalities induced by infection and iniury. Am Rev Respir Dis 1981; 124: 107-109.
21. Gerrard CS, Levandowski RA, Gerrity TR, Yeates DB, Klein E. The acute effects of acute respiratory virus infection upon tracheal mucous transport. Arch Environ Health 1985; 40: 322-325.
22. Wilson R, Cole PJ. The effect of bacterial products on ciliary function. Am Rev Respir Dis 1988; 138: S49-S53.
23. Shemer-Avni Y, Lieberman D. Chlamydia pneumoniae-induced ciliostasis in ciliated bronchial epithelial cells. J Infect Dis 1995; 171: 1274-1278.
24. Fujihara K, Yamanaka N, Bernstein JM, Ogra PL, Hard R. Morphologic and motility changes of nasal cilia in primary culture caused by Haemophilus influenzae. Ann Otol Rhinol Laryngol 1996; 105: 452-457.