Cytokine removal during continuous renal replacement therapy: An ex vivo comparison of convection and diffusion

International Journal of Artificial Organs

Volumn 27, Issue 5, 2004, Pages 388-397

  Cole, L ^a   Bellomo, Rinaldo ^a   Davenport, P ^b   Tipping, P ^b   Ronco, C ^c  

^a AUSTIN HEALTH   (Australia)

^b MONASH MEDICAL CENTRE   (Australia)

^c SAN BORTOLO HOSPITAL   (Italy)

Author keywords

Adsorption; Cytokines; Hemodialysis; Hemofiltration; Interleukin 1; Interleukin 10; Interleukin 6; Interleukin 8; Tumor necrosis factor

Indexed keywords

ADSORPTION; BLOOD; GLYCOPROTEINS; HEMODIALYZERS; INTENSIVE CARE UNITS; PROTEINS;

CYTOKINES; HAEMODIALYSIS; HEMOFILTRATION; INTERLEUKIN 1Β; INTERLEUKIN-10; INTERLEUKIN-8; INTERLEUKIN1; INTERLEUKIN6 (IL6); RENAL REPLACEMENT THERAPIES; TUMOR NECROSIS FACTORS;

DIALYSIS;

CYTOKINE; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; POLYACRYLONITRILE; TUMOR NECROSIS FACTOR;

ADSORPTION KINETICS; ARTICLE; CALCULATION; CLEARANCE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOKINE RELEASE; EFFLUENT; EX VIVO STUDY; FILTRATION; HEMODIALYSIS; HEMOFILTRATION; HUMAN; HUMAN EXPERIMENT; IN VIVO STUDY; INTENSIVE CARE UNIT; INTERMETHOD COMPARISON; NORMAL HUMAN; ROOM TEMPERATURE; SOLUTE;

EID: 3042583475     PISSN: 03913988     EISSN: None     Source Type: Journal    
DOI: 10.1177/039139880402700507     Document Type: Article

References (23)

1. Schetz M. Evidence-based analysis of the role of hemofiltration in sepsis and multiorgan dysfunction syndrome. Curr Opin Crit Care 1997; 3: 434-41.
2. Bellomo R, Baldwin I, Ronco C. Rationale for extracorporeal blood purification therapies in sepsis. Curr Opin Crit Care 2000; 6: 446-50.
3. De Vriese AS, Colardyn FA, Philippe JJ, et al. Cytokine removal during continuous hemofiltration in septic patients. J Am Soc Nephrol 1999; 10: 846-53.
4. Kellum JA, Johnson JP, Kramer D, et al. Diffusive vs. convective therapy: Effects on mediators of inflammation in patients with severe systemic inflammatory response syndrome. Crit Care Med 1998; 26: 1995-2000.
5. Tetta C, Mariano F, Buades J, et al. Relevance of platelet-activating factor in inflammation and sepsis: mechanisms and kinetics of removal in extracorporeal treatments. Am J Kidney Dis 1997; 30 (suppl 4): S57-65.
6. Barrera P, Janssen EM, Demacker PNM, et al. Removal of interleukin 1β and tumor necrosis factor from human plasma by in vitro dialysis with polyacrylonitrile membranes. Lymphokine Cytokine Res 1992; 11: 99-104.
7. Nagaki M, Hughes RD, Lau JYN, et al. Removal of endotoxin and cytokines by adsorbents and the effect of plasma protein binding. Int J Artif Organs 1991; 14: 43-50.
8. Goldfarb S, Golper TA. Proinflammatory cytokines and hemofiltration membranes. J Am Soc Nephrol 1994; 5: 228-32.
9. Van Bommel EFH, Hesse CJ, Jutte NHPM, et al. Cytokine kinetics (TNF-α, IL-1β, IL-6) during continuous hemofiltration: a laboratory and clinical study. In: Sieberth HG, Stummvol HK, Kierdorf H, eds. Continuous extracorporeal treatment in multiple organ dysfunction syndrome. Contrib Nephrol Basel; Karger, 1995; 116: 62-75.
10. Brown A, Mehta RL. Effect of CAVH membranes on transmembrane flux of TNF-α (Abstract). J Am Soc Nephrol 1991; 2: A316.
11. Hack CE, Aarden LA, Thijs LG. Role of cytokines in sepsis. Adv Immunol 1997; 66: 101-95.
12. Lamarre J, Wollenberg GK, Gonias SL, et al. Biology of disease: Cytokine binding and clearance properties of proteinase-activated alpha 2-macroglobulin. Lab Invest 1991; 65: 3-14.
13. Heering P, Morgera S, Schmitz G, et al. Cytokine removal and cardiovascular hemodynamics in septic patients with continuous hemofiltration. Intensive Care Med 1997; 23: 288-96.
14. Lonneman G, Koch KM, Shaldon S, et al. Studies on the ability of hemodialysis membranes to induce, bind, and clear interleukin-1. J Lab Clin Med 1988; 112: 76-86.
15. Bellomo R, Tipping P, Boyce N. Interleukin-6 and interleukin-8 extraction during continuous venovenous hemodiafiltration in septic acute renal failure. Ren Fail 1995; 17: 457-66.
16. Silvester W, Honore P, Sieffert E, et al. Interleukins 6 and 8, tumor necrosis factor alpha and complement D clearance by polyacrylonitrile and polysulphone membranes during haemofiltration in critically ill patients (Abstract). Blood Purif 1997; 15: 127.
17. Hoffman JN, Hartl WH, Deppisch R, et al. Effect of hemofiltration on hemodynamics and systemic concentrations of anaphylatoxins and cytokines in human sepsis. Intensive Care Med 1996; 22: 1360-7.
18. Webb LMC, Ehrengruber MU, Clark-Lewis I, et al. Binding to heparan sulfate or heparin enhances neutrophil responses to interleukin 8. Proc Natl Acad Sci USA 1993; 90: 7158-62.
19. Thijs LG, Hack CE. Time course of cytokine levels in sepsis. Intensive Care Med 1995; 21: S258-S263.
20. Engstad CS, Gutteberg TJ, Osterud B. Modulation of blood cell activation by four commonly used anticoagulants. Thromb Haemost 1997; 77: 690-6.
21. Marchant A, Alegre ML, Hakim A, et al. Clinical and biological significance of interleukin-10 plasma levels in patients with septic shock. J Clin Immunol 1995; 15: 266-73.
22. Lowry SF, Moldawer LL, Calvano SE. Cytokine markers of the human response to sepsis. In: Vincent JL, ed. Yearbook of intensive care and emergency medicine 1994. Berlin: Springer-Verlag, 1994; 14: 14-23.
23. Langsdorf LJ, Zydney AL. Effect of blood contact on the transport properties of hemodialysis membranes: A two-layer membrane model. Blood Purif 1994; 12: 292-307.