Production of human osteoclasts in a three-dimensional bone marrow culture system

Biochemical Engineering Journal

Volumn 20, Issue 2-3, 2004, Pages 189-196

  Mantalaris, Athanasios ^a,c   Bourne, Patricia ^b   Wu, J H David ^a,b  

^a University of Rochester   (United States)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Bone marrow; Bone resorption; Human; Long term bone marrow culture; Osteoclast; Osteoclastogenesis; Parathyroid hormone; Three dimensional culture; Tissue engineering; Vitamin D3

Indexed keywords

BONE; CELL CULTURE; CELLS; PHYSIOLOGY; VITAMINS;

BONE MARROW; CELLULAR SIGNALS;

BIOCHEMICAL ENGINEERING;

ACID PHOSPHATASE; COLECALCIFEROL; GROWTH FACTOR; HYDROCORTISONE; TARTARIC ACID;

ARTICLE; BONE MARROW CULTURE; CELL CULTURE; CELL DENSITY; CELL STRUCTURE; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; MULTINUCLEAR CELL; OSTEOCLAST; OSTEOLYSIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STIMULATION; STROMA CELL;

EID: 3042558642     PISSN: 1369703X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bej.2003.09.020     Document Type: Article

References (39)

1. Hayashi S.-H., Yamane T., Miyamoto A., Hemmi H., Tagaya H., Tanio Y., Kanda H., Yamazaki H., Kunisada T. Commitment and differentiation of stem cells to the esteoclast lineage. Biochem. Cell. Biol. 76:1998;911-922
2. J.H. Jandl, Blood: Textbook of Hematology, Little Brown and Co., Boston, MA, 1987.
3. G.R. Mundy, Bone resorbing cells, in: M.J. Favus (Ed.), Primer on the Metabolic Bone Disease and Disorders of Mineral Metabolsim, Lippincott-Raven Publishers, Philadelphia, PA, 1996, pp. 16-23.
4. Tondravi M.M., McKercher S., Anderson K., Erdmann J.J., Quiroz M., Maki R., Teitelbaum S.L. Osteopetrosis in mice lacking haematopoietic transcription factor PU.1. Nature. 386:1997;81-84
5. Grigoriadis A.E., Wang Z., Cecchini M.G., Hofstetter W., Felix T., Fleisch H.A., Wagner E.F. c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling. Science. 266:1994;443-448
6. Kodama H., Yamasaki A., Nose M., Niida S., Ohgama Y., Abe M., Kumegawa M., Suda T. Congenital osteoclast deficiency in osteopetrotic (op/op) mice is cured by injections of macrophage colony stimulating factor. J. Exp. Med. 173:1991;269-272
7. Yasuda H., Shima N., Nakagawa N., Yamaguchi K., Kinosaki M., Mochizuki S., Tomoyasu A., Yano K., Gotto M., Murakami A., Tsuda E., Morinaga T., Higashio K., Udagawa N., Takahashi N., Suda T. Osteoclast differentiation factor is a ligand for osteoprotein/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc. Nat. Acad. Sci. U.S.A. 95:1998;3597-3602
8. McSheehy P.M.J., Chambers T.J. Osteoblastic cells mediate osteoclastic responsiveness to parathyroid hormone. Endocrinology. 118:1986;824-828
9. Hirayama T., Sabokbar A., Athanasou N.A. Effect of corticosteroids on human osteoclast formation and activity. J. Endocrinol. 175:2002;155-163
10. Hofbauer L.C., Gori F., Riggs B.L., Lacey D.L., Dunstand C.R., Spelsberg T.C., Khosla S. Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: potential paracrine mechanisms of glucocorticoid-induced osteoporosis. Endocrinology. 140:1999;4382-4392
11. Matsuzaki K., Udagawa N., Takahashi N., Yamaguchi K., Yasuda H., Shima N., Morinaga T., Toyama Y., Yabe Y., Higashio K., Suda T. Osteoclast differentiation factor (ODF) induces osteoclast-like cell formation in human peripheral blood mononuclear cell cultures. Biochem. Bioph. Res. Commun. 246:1998;199-204
12. Kurihara N., Chenu C., Miller M., Civin C., Roodman G.D. Identification of committed mononuclear precursors for osteoclast-like cells formed in long term human marrow cultures. Endocrinology. 126:1990;2733-2741
13. Thavarajah M., Evans D.B., Binderup L., Kanis J.A. 1, 25(OH)2D3 and calcipotriol (MC903) have similar effects on the induction of osteoclast-like cell formation in human bone marrow cultures. Biochem. Bioph. Res. Commun. 171:1990;1056-1063
14. Thavarajah M., Evans D.B., Kanis J.A. 1, 25(OH)2D3 induces differentiation of osteoclast-like cells from human bone marrow cultures. Biochem. Bioph. Res. Commun. 176:1991;1189-1195
15. Flanagan A.M., Horton M.A., Dorey E.L., Collins D.A., Evely R.S., Moseley J.M., Firkin F.C., Chambers T.J., Helfrich M.H., Martin T.J. An assessment of the ability of human bone-marrow cultures to generate osteoclasts. Int. J. Exp. Path. 73:1992;387-401
16. Koshihara Y., Hoshi K., Okawara R., Ishibashi H. Vitamin K stimulates osteoblastogenesis and inhibits osteoclastogenesis in human bone marrow cell culture. J. Endocrinol. 176:2003;339-348
17. Y. Hakeda, M. Kumegawa, The growth and culture of bone cells: osteoclastic, in: J.P. Bilezikian, L.G. Raisz, G.A. Rodan (Eds.), Principles of Bone Biology, Academic Press, San Diego, 1996, pp. 1217-1228.
18. Nesbitt S.A., Horton M.A. Trafficking of matrix collagens through bone-resorbing oscteoclasts. Science. 276:1997;266-269
19. Rieman D.J., McClung H.A., Dodds R.A., Hwang S.M., Lark M.W., Holmes S., James I.E., Drake F.H., Gowen M. Biosynthesis and processing of Cathepsin K in cultured human osteoclasts. Bone. 28:2001;282-289
20. Miyamoto A., Higuchi Y., Mori K., Ito M., Tsurudome M., Nishio M., Yamada H., Sudo A., Kato K., Uchida A., Ito Y. Human osteosarcoma-derived cell lines produce soluble factor(s) that induces differentiation of blood monocytes to osteoclast-like cells. Int. Immunol. 2:2002;25-38
21. Scheven B.A.A., Marshall D., Aspden R.M. In vitro behaviour of human osteoblasts on denton and bone. Cell Biol. Int. 26:2002;337-346
22. Mantalaris A., Wu J.H.D. Developing an ex vivo mimic of bone marrow: a three-dimensional bone marrow bioreactor. BICC. 2:1995;12-15
23. Mantalaris A., Keng P., Bourne P., Chang A.Y.C., Wu J.H.D. Engineering a human bone marrow model: a case study on ex vivo erythropoiesis. Biotechnol. Progr. 14:1998;126-133
24. Wang T.Y., Brennan J.K., Wu J.H.D. Multilineal hemopoiesis in a three-dimensional murine long-term bone marrow culture. Exp. Hematol. 23:1995;26-32
25. I. Lefkovits (Ed.), Immunology Methods Mannual: The Comprehensive Sourcebook of Techniques, Academic Press, San Diego, 1997.
26. G.L. Humason, Animal Tissue Techniques, Freeman, San Fransisco, 1967.
27. A. Johnstone, R. Thorpe, Immunohistochemistry in Practice, Blackwell Science, Oxford, UK, 1996.
28. Deldar A., Lewis H., Bloom J. Electron microscopic study of the unique features and structural-morphologic relationship of canine bone marrow. Am. J. Vet. Res. 50:1989;136-144
29. D. Zucker-Franklin, M.F. Greaves, C.E. Grossi, A.M. Marmont (Eds.), Atlas of Blood Cells: Function and Pathology, Lea & Febiger, Philadelphia, 1988.
30. Anselme K. Osteoblast behaviour on biomaterials. Biomaterials. 21:2000;667-681
31. Deligianni D.D., Katsala N.D., Koutsoukos P.G., Missirlis Y.F. Effect of surface roughness of hydroxyapatite on human bone marrow adhesion, proliferation, differentiation and detachment growth. Biomaterials. 22:2001;87-96
32. Popoff S.N., Marks S.C. Congenitally osteopetrotic (OS OS) rabbits are not cured by bone-marrow transplantation from normal littermates. Am. J. Anatomy. 192:1991;274-280
33. Quinn J.M., Neale S., Fujikawa Y., McGee J.O., Athanasou N.A. Human osteoclast formation from blood monocytes. Calcif. Tissue Int. 62:1998;527-531
34. Takahashi S., Reddy S.V., Dallas M., Devlin R., Chou J.Y., Roodman G.D. Development and characterization of a human marrow stromal cell line that enhances osteoclast-like cell formation. Endocrinology. 136:1995;1441-1449
35. Choi Y., Woo K.M., Ko S.-H., Lee Y.J., Park S.-J., Kim H.-M., Kwon B.S. Osteoclastogenesis is enhanced by activated B cells but suppressed by activated CD8+ T cells. Eur. J. Immunol. 31:2001;2179-2188
36. Dorshkind K. In vitro differentiation of B lymphocytes from primitive hemopoietic precursors present in long-term bone marrow cultures. J. Immunol. 136:1986;422-429
37. Takahashi N., Kukita T., MacDonald B.R., Bird A., Mundy G.R., McManus L.M., Miller M., Boyde A., Jones S.J., Roodman G.D. Osteoclast-like cells form in long-term human bone marrow but not in peripheral blood. J. Clin. Inv. 85:1989;543-550
38. Sarma U., Flanagan A.M. Macrophage colony-stimulating factor induces substantial osteoclast generation and bone resorption in human bone marrow cultures. Blood. 88:1996;2531-2540
39. L.A. Fitzpatrick, J.P. Bilezikian, Actions of parathyriod hormone, in: J.P. Bilezikian, L.G. Raisz, G.A. Rodan (Eds.), Principles of Bone Biology, Academic Press, San Diego, 1996, pp. 339-346.