White particulate matter found in blood collection bags consist of platelets and leukocytes

Transfusion

Volumn 44, Issue 7, 2004, Pages 959-966

  Rentas, Francisco J ^a   Macdonald, V W ^a   Rothwell, S W ^a   McFaul, S J ^a   Asher, L V ^a   Kennedy, A M ^a   Hmel, P J ^a   Meledandri, C J ^a   Salata, J M ^a   Harman, R W ^a   Reid, T J ^a  

^a WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BLOOD BANK; BLOOD FILTER; BLOOD FILTRATION; BLOOD STORAGE; BRIGHT FIELD MICROSCOPY; DIFFERENTIAL INTERFERENCE CONTRAST MICROSCOPY; ELECTRON MICROSCOPY; ERYTHROCYTE TRANSFUSION; EXAMINATION; FLOW CYTOMETRY; HUMAN; INFRARED SPECTROSCOPY; LEUKOCYTE; LEUKOFILTRATION; PARTICULATE MATTER; PHASE CONTRAST MICROSCOPE; PLASMA TRANSFUSION; RESERVOIR; THROMBOCYTE; WHITE PARTICULATE MATTER;

BLOOD PLATELETS; BLOOD SPECIMEN COLLECTION; BLOOD TRANSFUSION; CELL AGGREGATION; FILTRATION; FLOW CYTOMETRY; HUMANS; LEUKOCYTES; MICROSCOPY; SPECTROPHOTOMETRY, INFRARED;

EID: 3042554708     PISSN: 00411132     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1537-2995.2004.03398.x     Document Type: Article

References (19)

1. Red Cross investigates noninfectious particles in blood. AABB Press Release, January 31, 2003. Bethesda, MD: AABB.
2. Update regarding blood quarantine by American Red Cross Southern Region. AABB Press Release, February 3, 2003. Bethesda, MD: AABB.
3. Key and terminology as relates to atypical blood units. AABB Press Release, February 5, 2003. Bethesda, MD: AABB.
4. Statement of the American Red Cross concerning blood quarantine. American Red Cross Press Release, February 3, 2003. Washington, DC: American Red Cross.
5. Update from the AABB Interorganizational Task Force regarding white particulate matter. AABB Press Release, February 6, 2003. Bethesda, MD: AABB.
6. Robertson M, Boulton FE, Doughty R, et al. Macroaggregate formation in optimal additive red cells. Vox Sang 1985;49:259-66.
7. Results of survey on white particulate matter. Washington, DC: America's Blood Centers, February 19, 2003.
8. Swank RL. Alteration of blood on storage: measurement of adhesiveness of "aging" platelets and leukocytes and their removal by filtration. N Engl J Med 1961;265:728-33.
9. Reiss RF, Katz AJ. Microaggregate content and flow rates of packed red blood cells. Transfusion 1977;17:484-9.
10. Marshall BE, Wurzel HA, Neufeld GR, et al. Effects of Fenwal 4C2423 transfusion microfilter on microaggregates and other constituents of stored blood. Transfusion 1978;18:38-45.
11. Linko K. Observations on the removal of microaggregates from stored blood by centrifugation and filtration through a standard 170 micron transfusion filter. Transfusion 1983;23:310-2.
12. Reynolds, LO, Simon TL. Size distribution measurements of microaggregates in stored blood. Transfusion 1980;20:669-78.
13. Goldfinger D, Solis RT, Meryman HT. Microaggregates in frozen and saline washed red blood cells. Transfusion 1974;14:151-4.
14. Barrett J, de Jongh DS, Miller E, Litwin MS. Microaggregate formation in stored human packed cells: comparison with formation in stored whole blood and a method for their removal. Ann Surg 1976;183:109-13.
15. Gervin AS, Mason KG, Buckman RF. The source and removal of microaggregates in aged human blood and human blood components. Surg Gynecol Obstet 1975;141:582-6.
16. Information alert on particulate matter in blood bags. Washington, DC: Center for Biologics Evaluation Research, FDA, February 7, 2003.
17. Update on FDA's continuing investigation of particulate matter in blood shows normal blood components and no evidence for an increase in adverse events. FDA News, February 27, 2003.
18. Blood Products Advisory Committee meeting, June 19-20, 2003. Washington, DC: Center for Biologics Evaluation Research, FDA, 2003.
19. Update on particulate matter in blood bags. Washington, DC: Center for Biologics Evaluation and Research, FDA, October 31, 2003.