The Enhancement of Stereoselectivity of a Pd-Catalyzed Three-Component Cascade Reaction Using Parallel Synthesis and Multivariate Analysis

Journal of Laboratory Automation

Volumn 9, Issue 3, 2004, Pages 103-108

  Ross, Kate ^a   Grigg, Ron ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

experimental design; palladium; stereoselectivity

Indexed keywords

IODOBENZENE; MORPHOLINE; PALLADIUM COMPLEX;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MULTIVARIATE ANALYSIS; PRINCIPAL COMPONENT ANALYSIS; STEREOCHEMISTRY; SYNTHESIS;

EID: 3042551042     PISSN: 22110682     EISSN: 15402452     Source Type: Journal    
DOI: 10.1016/j.jala.2004.04.001     Document Type: Article

References (8)

1. Zimmer R. Dinesh C. U Nandanan E. Khan F. A. Palladium-catalyzed reactions of allenes. Chem. Rev. 2000, 100, 3067–3125.
2. Wold S. Sjoestroem M. Carlson R. Lundstedt T. Multivariate design. Anal. Chim. Acta 1986, 191, 17–32.
3. Carlson R. Lundstedt T. Albano C. Screening of suitable solvents in organic synthesis. Strategies for solvent selection. Acta. Chem. Scan. 1985, B39, 79–91.
4. Ballistreri F. P. Fortuna C. G. Musumarra G. Pavone D. Scire S. Principal properties (PPs) as solvent descriptors for multivariate optimization in organic synthesis: Specific PPs for ethers. ARKIVOC 2002, (xi), 54–64.
5. Chastrette M. Statistical study of solvent effects. I. Principles and applications to the evaluation of solvent parameters and to classification. Tetrahedron 1979, 35, 1441–1448.
6. Chastrette M. Rajzmann M. Chanon M. Purcell K. F. Approach to a general classification of solvents using a multivariate statistical treatment of quantitative solvent parameters. J. Am. Chem. Soc. 1985, 107, 1–11.
7. Abraham R. J. Bretscheider E. Medium Effects on Rotational and Conformational Equilibira. In Internal Rotation in Molecules; Wiley-Interscience, New York, 1974; pp 481–584.
8. Jorgensen W. L. Theoretical studies of medium effects on conformational equilibria. J. Phys. Chem. 1983, 87, 5304–5314.