Economic and programmatic aspects of congenital syphilis prevention

Bulletin of the World Health Organization

Volumn 82, Issue 6, 2004, Pages 402-409

  Schmid, George ^a  

^a WORLD HEALTH ORGANIZATION   (Switzerland)

Author keywords

Cost of illness; National health programs organization and administration; Pregnancy; Prenatal care; Prenatal diagnosis economics; Syphilis, Congenital prevention and control economics; Syphilis prevention and control economics; Treatment failure

Indexed keywords

DISEASE CONTROL; DISEASE TRANSMISSION; HEALTH CARE; PREGNANCY; SYPHILIS;

CONGENITAL SYPHILIS; COST CONTROL; COST EFFECTIVENESS ANALYSIS; ECONOMIC ASPECT; FEMALE; FETUS; FETUS DEATH; HEALTH PROGRAM; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; PRENATAL CARE; PRENATAL SCREENING; REVIEW; SYSTEMATIC REVIEW; VERTICAL TRANSMISSION;

COST-BENEFIT ANALYSIS; DISEASE TRANSMISSION, VERTICAL; FEMALE; HEALTH PRIORITIES; HUMANS; INFANT, NEWBORN; MASS SCREENING; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; PRENATAL CARE; PROGRAM DEVELOPMENT; SYPHILIS SERODIAGNOSIS; SYPHILIS, CONGENITAL; WORLD HEALTH;

EID: 3042525232     PISSN: 00429686     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (54)

1. United Nations Children's Fund. Mother-to-child transmission of HIV. A UNICEF Fact Sheet. New York: UNICEF; 2002.
2. De Cock KM, Fowler MG, Mercier E, de Vincenzi I, Saba J, Hoff E, et al. Prevention of mother-to-child HIV transmission in resource-poor countries: translating research into policy and practice. JAMA 2000;283:1175-82.
3. Gloyd S, Chai S, Mercer MA. Antenatal syphilis in sub-Saharan Africa: missed opportunities for mortality reduction. Health Policy & Planning 2001;16:29-34.
4. Schulz KF, Cates W Jr, O'Mara PR. Pregnancy loss, infant death, and suffering: legacy of syphilis and gonorrhoea in Africa. Genitourinary Medicine 1987;63:320-5.
5. Aiken CG. The causes of perinatal mortality in Bulawayo, Zimbabwe. Central African Journal of Medicine 1992;38:263-81.
6. Berman SM. Maternal syphilis: pathophysiology and treatment. Bulletin of the World Health Organization 2004;82 433-8.
7. Delport SD, van den Berg JH. On-site screening for syphilis at an antenatal clinic. South African Medical Journal 1998;88:43-4.
8. Patel A, Moodley D, Moodley J. An evaluation of on-site testing for syphilis. Tropical Doctor 2001;31:79-82.
9. Watson-Jones D, Changalucha J, Gumodoka B, Weiss H, Rusizoka M, Ndeki L, et al. Syphilis in pregnancy in Tanzania. I. Impact of maternal syphilis on outcome of pregnancy. Journal of Infectious Diseases 2002;186:940-7.
10. Bronzan R, Mwesgwa-Kayongo D, Narkunas D. Report to the South African Ministry of Health. Atlanta: Centers for Disease Control and Prevention; 2002.
11. Alexander JM, Sheffield JS, Sanchez PJ, Mayfield J, Wendel GD Jr. Efficacy of treatment for syphilis in pregnancy. Obstetrics and Gynecology 1999;93:5-8.
12. Watson-Jones D, Gumodoka B, Weiss H, Changalucha J, Todd J, Mugeye K, et al. Syphilis in pregnancy in Tanzania. II. The effectiveness of antenatal syphilis screening and single-dose benzathine penicillin treatment for the prevention of adverse pregnancy outcomes. Journal of Infectious Diseases 2002;186:948-57.
13. Walker DG, Walker GJ. Forgotten but not gone: the continuing scourge of congenital syphilis. Lancet Infectious Diseases 2002;2:432-6.
14. Williams K. Screening for syphilis in pregnancy: an assessment of the costs and benefits. Community Medicine 1985;7:37-42.
15. Stray-Pedersen B. Economic evaluation of maternal screening to prevent congenital syphilis. Sexually Transmitted Diseases 1983;10:167-72.
16. Bryce RL, Pritchard RC. The cost of routine antenatal screening for syphilis. Australian & New Zealand Journal of Obstetrics & Gynaecology 1981;21:211-13.
17. Connor N, Roberts J, Nicoll A. Strategic options for antenatal screening for syphilis in the United Kingdom: a cost effectiveness analysis. Journal of Medical Screening 2000;7:7-13.
18. Garland SM, Kelly VN. Is antenatal screening for syphilis worth while? Medical Journal of Australia 1989;151:368.
19. Bateman DA, Phibbs CS, Joyce T, Heagarty MC. The hospital cost of congenital syphilis. Journal of Pediatrics 1997;130:752-8.
20. Fonck K, Claeys P, Bashir F, Bwayo J, Fransen L, Temmerman M. Syphilis control during pregnancy: effectiveness and sustainability of a decentralized program. American Journal of Public Health 2001;91:705-7.
21. Hira SK, Bhat GJ, Chikamata DM, Nkowane B, Tembo G, Perine PL, et al. Syphilis intervention in pregnancy: Zambian demonstration project. Genitourinary Medicine 1990;66:159-64.
22. Terris-Prestholt F, Watson-Jones D, Mugeye K, Kumaranayake L, Ndeki L, Weiss H, et al. Is antenatal syphilis screening still cost effective in sub-Saharan Africa. Sexually Transmitted Infections 2003;79:375-81.
23. World Bank. World Development Report 1993: Investing in Health. Washington (DC): World Bank; 1993.
24. Phaosavasdi S, Snidvongs W, Thasanapradit P, Asavapiriyanon S, Ungthavorn P, Bhongsvej S, et al. Cost-benefit analysis of diagnosis and treatment of syphilis in pregnant women. Journal of the Medical Association of Thailand 1987;70:90-95.
25. Mullick S, Htun Y, Temmerman M, Ndowa F, Broutet N. Controlling congenital syphilis in the era of HIV/AIDS. Bulletin of the World Health Organization 2004;82:431-2.
26. Gust DA, Levine WC, St Louis ME, Braxton J, Berman SM. Mortality associated with congenital syphilis in the United States, 1992-1998. Pediatrics 2002;109:E79.
27. St. Lawrence J. Proceedings of the 2000 National STD Prevention Conference. Milwaukee (WI) USA. Atlanta: Centers for Disease Control and Prevention; 2003.
28. Warner L, Rochat RW, Fichtner RR, Stoll BJ, Nathan L, Toomey KE. Missed opportunities for congenital syphilis prevention in an urban southeastern hospital. Sexually Transmitted Diseases 2001;28:92-8.
29. Fitzgerald DW, Behets FM, Lucet C, Roberfroid D. Prevalence, burden, and control of syphilis in Haiti's rural Artibonite region. International Journal of Infectious Diseases 1998;2:127-31.
30. Lim CT, Koh MT, Sivanesaratnam V. Early congenital-syphilis a continuing problem in Malaysia. Medical Journal of Malaysia 1995;50:131-5.
31. Bulatao RA, Ross JA. Rating maternal and neonatal health services in developing countries. Bulletin of the World Health Organization 2002;80:721-7.
32. World Health Organization. Chapter 5: Global, Regional and National Estimates. In: Coverage of maternity care: a listing of available information. 4th ed. Geneva: World Health Organization; 1997. p.1-136.
33. Southwick KL, Blanco S, Santander A, Estenssoro M, Torrico F, Seoane G, et al. Maternal and congenital syphilis in Bolivia, 1996: prevalence and risk factors. Bulletin of the World Health Organization 2001;79:33-42.
34. Webber MP, Lambert G, Bateman DA, Hauser WA. Maternal risk factors for congenital syphilis: a case-control study. American Journal of Epidemiology 1993;137:415-22.
35. Lumbiganon P, Piaggio G, Villar J, Pinol A, Bakketeig L, Bergsjo P, et al. The epidemiology of syphilis in pregnancy. International Journal of STD & AIDS 2002;13:486-94.
36. McDermott J, Steketee R, Larsen S, Wirima J. Syphilis-associated perinatal and infant mortality in rural Malawi. Bulletin of the World Health Organization 1993;71:773-80.
37. Mobley JA, McKeown RE, Jackson KL, Sy F, Parham JS, Brenner ER. Risk factors for congenital syphilis in infants of women with syphilis in South Carolina. American Journal of Public Health 1998;88:597-602.
38. Swingler GH, Van Coeverden de Groot HA. The antenatal prevention of congenital syphilis in a peri-urban settlement. South African Medical Journal 1993;83:34-5.
39. Rotchford K, Lombard C, Zuma K, Wilkinson D. Impact on perinatal mortality of missed opportunities to treat maternal syphilis in rural South Africa: baseline results from a clinic randomized controlled trial. Tropical Medicine & International Health 2000;5:800-4.
40. World Health Organization, United Nations Children's Fund. Antenatal care in developing countries: promises, achievements and missed opportunities: an analysis of trends, levels and differentials, 1990-2001. Geneva: World Health Organization; 2003. Available from: URL: http://www.who.int/reproductive-health/ docs/antenatal_care.pdf
41. Maggwa BN, Askev I, Mugwe E, Hagembe B, Homan R. A case study of Nairobi City Council's Decentralised Syphilis Screening Programme in Antenatal Clinics. Population Council, Nairobi City Council: Family Health International; 2001.
42. West B, Walraven G, Morison L, Brouwers J, Bailey R. Performance of the rapid plasma reagin and the rapid syphilis screening tests in the diagnosis of syphilis in field conditions in rural Africa. Sexually Transmitted Infections 2002;78:282-5.
43. Delport SD. On-site screening for maternal syphilis in an antenatal clinic. South African Medical Journal 1993;83:723-4.
44. Peeling R, Htun Y. Diagnostic tools for preventing and managing maternal and congenital syphilis: an overview. Bulletin of the World Health Organization 2004;82:439-46.
45. Donders GG, Desmyter J, Hooft P, Dewet GH. Apparent failure of one injection of benzathine penicillin G for syphilis during pregnancy in human immunodeficiency virus-seronegative African women. Sexually Transmitted Diseases 1997;24:94-101.
46. Wilkinson D, Sach M, Connolly C. Epidemiology of syphilis in pregnancy in rural South Africa: opportunities for control. Tropical Medicine & International Health 1997;2:57-62.
47. Gichangi P, Fonck K, Sekande-Kigondu C, Ndinya-Achola J, Bwayo J, Kiragu D, et al. Partner notification of pregnant women infected with syphilis in Nairobi, Kenya. International Journal of STD & AIDS 2000;11:257-61.
48. Mlisana KP, Monokoane S, Hoosen AA, Moodley J, Adhikari M, Taylor L. Syphilis in the 'unbooked' pregnant woman. South African Medical Journal 1992;82:18-20.
49. Plan of action for the elimination of congenital syphilis. Washington (DC): Pan American Health Organization; 1995. PAHO/WHO/CE116/14, 1995.
50. World Health Organization. Antenatal care report of a technical working group. Geneva: World Health Organization; 1994.
51. World Health Organization. WHO antenatal care randomized trial: manual for the implementation of the new model. Geneva: World Health Organization; 2002. WHO document WHO/RHR/01.30.
52. Temmerman M, Fonck K, Bashir F, Inion I, Ndinya-Achola JO, Bwayo J, et al. Declining syphilis prevalence in pregnant women in Nairobi since 1995: another success story in the STD field? International Journal of STD & AIDS 1999;10:405-8.
53. Temmerman M, Mohamedali F, Fransen L. Syphilis prevention in pregnancy: an opportunity to improve reproductive and child health in Kenya. Health policy and planning 1993;8:122-7.
54. Qolohle DC, Hoosen AA, Moodley J, Smith AN, Mlisana KP. Serological screening for sexually transmitted infections in pregnancy: is there any value in re-screening for HIV and syphilis at the time of delivery? Genitourinary Medicine 1995;71:65-7.