Packed column supercritical fluid chromatography of a peroxysome proliferator-activating receptor agonist drug: Achiral and chiral purity of substance, formulation assay and its enantiomeric purity

Journal of Chromatography A

Volumn 1042, Issue 1-2, 2004, Pages 173-180

  Gyllenhaal, Olle ^a  

^a ASTRAZENECA R AND D   (Sweden)

Author keywords

Enantiomer separation; Peroxysome proliferator activating receptor agonist; Pharmaceutical analysis; Supercritical fluid chromatography

Indexed keywords

ACIDITY; ALCOHOLS; CARBOXYLIC ACIDS; DRUG PRODUCTS; IMPURITIES; SURFACE PHENOMENA;

CHIRAL PURITY; ENANTIOMETRIC PURITY; PROLIFERATION; SUPERCRITICAL FLUID CHROMATOGRAPHY (SFC);

COLUMN CHROMATOGRAPHY;

2 PROPANOL; CITRIC ACID; METHANOL; PENTANOL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST;

ANALYTIC METHOD; ARTICLE; CHIRALITY; DRUG FORMULATION; DRUG PURIFICATION; DRUG PURITY; ENANTIOMER; ENANTIOSELECTIVITY; PRIORITY JOURNAL; SEPARATION TECHNIQUE; SUPERCRITICAL FLUID CHROMATOGRAPHY;

BUFFERS; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, LIQUID; DRUG CONTAMINATION; HYDROGEN-ION CONCENTRATION; INDICATORS AND REAGENTS; ION EXCHANGE RESINS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SOLUTIONS; SOLVENTS; SPECTROPHOTOMETRY, ULTRAVIOLET; STEREOISOMERISM; TARTRATES; TRANSCRIPTION FACTORS; WATER;

EID: 3042520936     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2004.05.035     Document Type: Article

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