Application of the regression of offspring on mid-parent method to detect associations between single-nucleotide polymorphisms and the beta 2 electroencephalogram phenotype in the COGA data

BMC Genetics

Volumn 6, Issue SUPPL.1, 2005, Pages

  Roy Gagnon, Marie Hélène ^a   Mathias, Rasika A ^a   Wilson, Alexander F ^a  

^a NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ALCOHOLISM; ARTICLE; CHROMOSOME 1; CHROMOSOME 11; CHROMOSOME 12; CHROMOSOME 15; CHROMOSOME 16; CHROMOSOME 17; CHROMOSOME 18; CHROMOSOME 19; CHROMOSOME 2; CHROMOSOME 5; CHROMOSOME 6; CHROMOSOME 7; CHROMOSOME 8; CHROMOSOME ANALYSIS; CONTROLLED STUDY; ELECTROENCEPHALOGRAPHY; FEMALE; GENE FREQUENCY; GENETIC ANALYSIS; GENOME ANALYSIS; HERITABILITY; HUMAN; LINKAGE ANALYSIS; MALE; PHENOTYPE; PROGENY; QUANTITATIVE STUDY; REGRESSION ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; ADOLESCENT; CAUCASIAN; COOPERATION; GENETIC DATABASE; GENETIC PREDISPOSITION; GENETICS; METHODOLOGY; PARENT; PATHOPHYSIOLOGY;

ADOLESCENT; ADULT; ALCOHOLISM; COOPERATIVE BEHAVIOR; DATABASES, GENETIC; ELECTROENCEPHALOGRAPHY; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; PARENTS; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; REGRESSION ANALYSIS;

EID: 30344482139     PISSN: None     EISSN: 14712156     Source Type: Journal    
DOI: 10.1186/1471-2156-6-S1-S56     Document Type: Article

References (12)

1. Porjesz B, Begleiter H, Wang K, Almasy L, Chorlian DB, Stimus AT, Kuperman S, O'Connor SJ, Rohrbaugh J, Bauer LO, Edenberg HJ, Goate A, Rice JP, Reich T: Linkage and linkage disequilibrium mapping of ERP and EEG phenotypes. Biol Psychol 2002, 61:229-248.
2. Ghosh S, Begleiter H, Porjesz B, Chorlian DB, Edenberg HJ, Foroud T, Goate A, Reich T: Linkage mapping of beta 2 EEG waves via non-parametric regression. Am J Med Genet 2003, 118B:66-71.
3. Edenberg HJ, Dick DM, Xuei X, Tian H, Almasy L, Bauer LO, Crowe RR, Goate A, Hesselbrock V, Jones K, Kwon J, Li TK, Nurnberger JI Jr, O'Connor SJ, Reich T, Rice J, Schuckit MA, Porjesz B, Foroud T, Begleiter H: Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations. Am J Hum Genet 2004, 74:705-714.
4. Song J, Koller DL, Foroud T, Carr K, Zhao J, Rice J, Nurnberger JI Jr, Begleiter H, Porjesz B, Smith TL, Schuckit MA, Edenberg HJ: Association of GABA(A) receptors and alcohol dependence and the effects of genetic imprinting. Am J Med Genet B Neuropsychiatr Genet 2003, 117:39-45.
5. Pugh EW, Papanicolaou GJ, Justice CM, Roy-Gagnon MH, Sorant AJ, Kingman A, Wilson AF: Comparison of variance components, methods for SNP markers. Genet Epidemiol 2001, 21(Suppl 1):S794-S799.
6. Roy-Gagnon M-H: Theoretical and applied investigations of a regression of offspring on mid-parent approach: Familial idiopathic scoliosis. In Ph.D. thesis Johns Hopkins University, Department of Epidemiology; 2004.
7. SAS Institute Inc: SAS Release 8.2 Cary, NC, USA; 2001.
8. Ihaka R, Gentleman R: R: A language for data analysis and graphics. J Computat Graph Statist 1996, 5:299-314.
9. Single Nucleotide Polymorphism Database [http://www.ncbi.nlm.nih.gov/SNP/]
10. Statistical Solutions Ltd: S.A.G.E. Statistical Analysis for Genetic Epidemiology Cork, Ireland; 2002.
11. Dick DM, Foroud T: Candidate genesAfor alcohol dependence: a review of genetic evidence from human studies. Alcohol Clin Exp Res 2003, 27:868-879.
12. Schumann G, Spanagel R, Mann K: Candidate genes for alcohol dependence: animal studies. Alcohol Clin Exp Res 2003, 27:880-888.