A pilot evaluation of the use of tissue microarrays for quantitation of target distribution in drug discovery pathology

Experimental and Toxicologic Pathology

Volumn 57, Issue 3, 2006, Pages 181-193

  McKay, Jennifer S ^a   Bigley, Alison ^a   Bell, Alex ^a   Jenkins, Richard ^a   Somers, Rebecca ^a   Brocklehurst, Simon ^a   White, Anne ^a   Goodwin, Louise ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

Histopathology; Image analysis; Immunohistochemistry; In situ hybridisation; Quantitative; Tissue microarray

Indexed keywords

MESSENGER RNA; OLIGONUCLEOTIDE; PEPTIDYLGLYCINE AMIDATING MONOOXYGENASE; PROTEIN KINASE; PROTEIN KINASE P CIP2; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL POPULATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOG; FEMALE; HISTOPATHOLOGY; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; RAT; TISSUE DISTRIBUTION; TISSUE MICROARRAY;

ANIMALIA; CANIS FAMILIARIS;

EID: 30344479446     PISSN: 09402993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etp.2005.09.002     Document Type: Article

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