Decreased inhibitory activity of prothrombin to calcium oxalate crystallization by specific chemical modification of its gamma-carboxyglutamic acid residues

Urology

Volumn 67, Issue 1, 2006, Pages 201-203

  Liu, Jihong ^a   Wang, Tao ^a   Chen, Junhui ^a   Wang, Shaogang ^a   Ye, Zhangqun ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

4 CARBOXYGLUTAMIC ACID; 4 METHYLGLUTAMIC ACID; CALCIUM OXALATE; FORMALDEHYDE; MORPHOLINE; PROTHROMBIN;

ARTICLE; CHEMICAL MODIFICATION; CRYSTALLIZATION; DRUG ACTIVITY; MINIMUM INHIBITORY CONCENTRATION; PRIORITY JOURNAL; RADIOACTIVITY; URINE LEVEL;

1-CARBOXYGLUTAMIC ACID; CALCIUM OXALATE; CRYSTALLIZATION; PROTHROMBIN;

EID: 30344479192     PISSN: 00904295     EISSN: 15279995     Source Type: Journal    
DOI: 10.1016/j.urology.2005.07.058     Document Type: Article

References (8)

1. B. Furie, B.C. Furie Molecular basis of vitamin K-dependent gamma-carboxylation Blood 75 1990 1753 1762
2. A.M. Stapleton, T.L. Timme, R.L. Ryall Gene expression of prothrombin in the human kidney and its potential relevance to kidney stone disease Br J Urol 81 1998 666 671
3. P.K. Grover, R.L. Ryall Inhibition of calcium oxalate crystal growth and aggregation by prothrombin and its fragments in vitro relationship between protein structure and inhibitory activity Eur J Biochem 263 1999 50 56
4. S.F. Wright, C.D. Bourne, R.A. Hoke A method for specific chemical modification of gamma-carboxyglutamic acid residues in proteins Anal Biochem 139 1984 82 90
5. B. Furie, B.A. Bouchard, B.C. Furie Vitamin K-dependent biosynthesis of gamma-carboxyglutamic acid Blood 93 1999 1798 1808
6. S.P. Bajaj, P.A. Price, W.A. Russell Decarboxylation of gamma-carboxyglutamic acid residues in human prothrombin stoichiometry of calcium binding to gamma-carboxyglutamic acid in prothrombin J Biol Chem 257 1982 3726 3731
7. P.K. Grover, R.L. Moritz, R.J. Simpson Inhibition of growth and aggregation of calcium oxalate crystals in vitro - a comparison of four human proteins Eur J Biochem 253 1998 637 644
8. J. Liu, J. Chen, T. Wang Effects of urinary prothrombin fragment 1 in the formation of calcium oxalate calculus J Urol 173 2005 113 116