Parent-of-origin, imprinting, mitochondrial, and X-linked effects in traits related to alcohol dependence: Presentation Group 18 of Genetic Analysis Workshop 14

Genetic Epidemiology

Volumn 29, Issue SUPPL., 2005, Pages

  Strauch, Konstantin ^a,b   Baur, Max P ^a  

^a UNIVERSITY OF BONN   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Alcoholism; Allele sharing; Haseman Elston regression; Linkage analysis; Mitochondrion; MOD score; Sex specific map; Variance components; X chromosome

Indexed keywords

ALCOHOLISM; CHROMOSOME 10; CHROMOSOME 11; CHROMOSOME 12; CHROMOSOME 21; CONFERENCE PAPER; FEMALE; GENE IDENTIFICATION; GENE LOCUS; GENE MAPPING; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC MARKER; GENETIC TRAIT; GENOME IMPRINTING; HUMAN; HUMAN CELL; MALE; MICROSATELLITE MARKER; MITOCHONDRION; PARENT; PHENOTYPE; SEX DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM; X CHROMOSOME LINKAGE;

ALCOHOLISM; ALLELES; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, X; CYTOGENETIC ANALYSIS; DATA INTERPRETATION, STATISTICAL; GENETIC PREDISPOSITION TO DISEASE; GENOMIC IMPRINTING; GENOTYPE; HUMANS; MITOCHONDRIA;

EID: 30344473653     PISSN: 07410395     EISSN: None     Source Type: Journal    
DOI: 10.1002/gepi.20121     Document Type: Conference Paper

References (31)

1. Almasy L, Blangero J. 1998. Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet 62:1198-1211.
2. American Psychiatric Association. 1987. Diagnostic and Statistical Manual of Mental Disorders. Third edition, revised. Washington, DC: American Psychiatric Association Press.
3. American Psychiatric Association. 1994. Diagnostic and Statistical Manual of Mental Disorders. Fourth Edition, Washington, DC: American Psychiatric Association Press.
4. Bautista JF, Quade SRE, Parrado AR, Goddard KAB. 2005. Linkage analysis of alcoholism-related electrophysiological phenotypes: genome scans with microsatellites compared to single-nucleotide polymorphisms. BMC Genet [Suppl] 6:156.
5. Bulmer MG. 1985. The mathematical theory of quantitative genetics. New York: Oxford University Press.
6. Clerget-Darpoux F, Bonaïti-Pellié C, Hochez J. 1986. Effects of misspecifying genetic parameters in lod score analysis. Biometrics 42:393-399.
7. Czerwinski SA, Williams JT, Demerath EW, Towne B, Siervogel RM, Blangero J. 2001. Does accounting for mitochondrial genetic variation improve the fit of genetic models? Genet Epidemiol [Suppl] 21:779-782.
8. Edenberg HJ, Bierut LJ, Boyce P, Cao M, Cawley S, Chiles R, Doheny KF, Hansen M, Hinrichs T, Jones K, Kelleher M, Kennedy GC, Liu G, Marcus G, McBride C, Murray SS, Oliphant A, Pettengill J, Porjesz B, Pugh EW, Rice JP, Rubano T, Shannon S, Steeke R, Tischfield JA, Tsai Y-Y, Zhang C, Begleiter H. 2005. Description of the data from the Collaborative Study on the Genetics of Alcoholism (COGA) and single-nucleotide polymorphism genotyping for Genetic Analysis Workshop 14. BMC Genet [Suppl] 6:2.
9. Ekstrøm CT. 2004. Multipoint linkage analysis of quantitative traits on sex-chromosomes. Genet Epidemiol 26:218-230.
10. Feighner JP, Robins E, Guze SB, Woodruff Jr RA, Winokur G, Munoz R. 1972. Diagnostic criteria for use in psychiatric research. Arch Gen Psychiatry 26:57-63.
11. Gudbjartsson DF, Jonasson K, Frigge ML, Kong A. 2000. Allegro, a new computer program for multipoint linkage analysis. Nat Genet 25:12-13.
12. Karason A, Gudjonsson JE, Upmanyu R, Antonsdottir AA, Hauksson VB, Runasdottir EH, Jonsson HH, Gudbjartsson DF, Frigge ML, Kong A, Stefansson K, Valdimarsson H, Gulcher JR. 2003. A susceptibility gene for psoriatic arthritis maps to chromosome 16q: evidence for imprinting. Am J Hum Genet 72:125-131.
13. Kent JW Jr, Lease LR, Mahaney MC, Dyer TD, Almasy L, Blangero J. 2005. X chromosome effects and their interactions with mitochondrial effects: the COGA study. BMC Genet [Suppl] 6:157.
14. Kong A, Cox NJ. 1997. Allele-sharing models: LOD scores and accurate linkage tests. Am J Hum Genet 61:1179-1188.
15. Lathrop GM, Lalouel JM, Julier C, Ott J. 1984. Strategies for multilocus linkage analysis in humans. Proc Natl Acad Sci USA 81:3443-3446.
16. Lease LR, Winnier DA, Williams JT, Dyer TD, Almasy L, Mahaney MC. 2005. Mitochondrial genetic effects on latent class variables associated with susceptibility to alcoholism. BMC Genet [Suppl] 6:158.
17. Lemire M. 2005. A simple nonparametric multipoint procedure to test for linkage through mothers or fathers as well as imprinting effects in the presence of linkage. BMC Genet [Suppl] 6:159.
18. Liu X-Q, Greenwood CMT, Wang K-S, Paterson AD. 2005. A genome scan for parent-of-origin linkage effects in alcoholism. BMC Genet [Suppl] 6:160.
19. Paterson AD, Naimark DMJ, Petronis A. 1999. The analysis of parental origin of alleles may detect susceptibility loci for complex disorders. Hum Hered 49:197-204.
20. S.A.G.E. 2004. Statistical Analysis for Genetic Epidemiology (S.A.G.E.), version 5.0. Department of Epidemiology and Biostaristics, MetroHealth Campus. Cleveland, OH: Case Western Reserve University.
21. Shete S, Amos CI. 2002. Testing for genetic linkage in families by a variance-components approach in the presence of genomic imprinting. Am J Hum Genet 70:751-757.
22. Shete S, Yu R. 2005. Genetic imprinting analysis for alcoholism genes using variance components approach. BMC Genet [Suppl] 6:161.
23. Shete S, Zhou X, Amos CI. 2003. Genomic imprinting and linkage test for quantitative-trait loci in extended pedigrees. Am J Hum Genet 73:933-938.
24. Sobel E, Lange K. 1996. Descent graphs in pedigree analysis: applications to haplotyping, location scores, and marker-sharing statistics. Am J Hum Genet 58:1323-1337.
25. Song J, Koller DL, Foroud T, Carr K, Zhao J, Rice J, Nurnberger JI Jr, Begleiter H, Porjesz B, Smith TL, Schuckit MA, Edenberg HJ. 2003. Association of GABA(A) receptors and alcohol dependence and the effects of genetic imprinting. Am J Med Genet 117:39-45.
26. Strauch K. 2003. Parametric linkage analysis with automatic optimization of the disease model parameters. Am J Hum Genet [Suppl] 73:2624.
27. Strauch K. 2005. Gene mapping, imprinting and epigenetics. In: Jorde LB, Little PFR, Dunn MJ, Subramaniam S, editors. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. Chichester, UK: John Wiley & Sons, Ltd. Vol 1, p 379-388.
28. Strauch K, Fimmers R, Kurz T, Deichmann KA, Wienker TF, Baur MP. 2000a. Parametric and nonparametric multipoint linkage analysis with imprinting and two-locus-trait models: application to mite sensitization. Am J Hum Genet 66:1945-1957.
29. Strauch K, Fimmers R, Wienker TF, Baur MP, Cichon S, Propping P, Nöthen MM. 2000b. Reply to Paterson. Mol Psychiatry 5:126-127.
30. Strauch K, Fürst R, Rüschendorf F, Windemuth C, Dietter J, Plaquer A, Baur MP, Wienker TF. 2005. Linkage analysis of alcohol dependence using MOD scores. BMC Genet [Suppl] 6:162.
31. Weeks DE, Sobel E, O'Connell JR, Lange K. 1995. Computer programs for multilocus haplotyping of general pedigrees. Am J Hum Genet 56:1506-1507.