The crystal structure and physicochemical characteristics of 2-hydroxy-N-[3(5)-pyrazolyl]-1,4-naphthoquinone-4-imine, a new antitrypanosomal compound

AAPS PharmSciTech

Volumn 6, Issue 4, 2005, Pages

  Sperandeo, Norma R ^a   Karlsson, Alicia ^a   Cuffini, Silvia ^b   Pagola, Silvina ^c   Stephens, Peter W ^c  

^a UNIVERSIDAD NACIONAL DE CÓRDOBA   (Argentina)

^b Centro de Excelencia en Productos y Procesos de Cordoba   (Argentina)

^c STONY BROOK UNIVERSITY   (United States)

Author keywords

Anti Trypanosoma cruzi agent; Crystal structure; Differential scannina calorimetry; High resolution X ray powder diffraction

Indexed keywords

2 HYDROXY N [3(5) PYRAZOLYL] 1,4 NAPHTHOQUINONE 4 IMINE; ANTITRYPANOSOMAL AGENT; DIMETHYL SULFOXIDE; METHANOL; OXYGEN; UNCLASSIFIED DRUG; WATER; ANTIPROTOZOAL AGENT; IMINE; NAPHTHOQUINONE;

ARTICLE; CHEMICAL INTERACTION; CRYSTAL STRUCTURE; DIFFERENTIAL SCANNING CALORIMETRY; HYDROGEN BOND; INFRARED SPECTROSCOPY; MICROSCOPY; NONHUMAN; PHYSICAL CHEMISTRY; PRISM; SOLID; THERMAL ANALYSIS; THERMOGRAVIMETRY; TRYPANOSOMA CRUZI; TRYPANOSOMIASIS; X RAY POWDER DIFFRACTION; CHEMISTRY; CRYSTALLIZATION;

ANTIPROTOZOAL AGENTS; CHEMISTRY, PHYSICAL; CRYSTALLIZATION; IMINES; NAPHTHOQUINONES;

EID: 30344467547     PISSN: 15309932     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/pt060482     Document Type: Article

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