High glucose exacerbates neutrophil adhesion to human retinal endothelial cells

Experimental Eye Research

Volumn 82, Issue 1, 2006, Pages 179-182

  Hirata, Fumisato ^a   Yoshida, Munenori ^a   Ogura, Yuichiro ^a  

^a NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

Author keywords

Diabetic retinopathy; Intercellular adhesion molecule 1; Leukocyte; Protein kinase C; Vascular inflammation

Indexed keywords

12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; GLUCOSE; INTERCELLULAR ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 1 ANTIBODY; LEVO GLUCOSE; PROTEIN KINASE C INHIBITOR;

ARTICLE; CELL ADHESION; CONTROLLED STUDY; DIABETIC RETINOPATHY; DRUG INHIBITION; ENDOTHELIUM CELL; ENZYME ACTIVATION; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN CELL; NEUTROPHIL; NORMAL HUMAN; PRIORITY JOURNAL; RETINA CELL;

ANTIBODIES, MONOCLONAL; CARBAZOLES; CELL ADHESION; CELLS, CULTURED; DIABETIC RETINOPATHY; ENDOTHELIAL CELLS; GLUCOSE; HUMANS; INDOLES; INTERCELLULAR ADHESION MOLECULE-1; NEUTROPHILS; PROTEIN KINASE C; RETINA;

EID: 30344466376     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2005.08.022     Document Type: Article

References (18)

1. A.P. Adamis Is diabetic retinopathy an inflammatory disease? Br. J. Ophthalmol. 86 2002 363 365
2. F.C. Barouch, K. Miyamoto, J.R. Allport, K. Fujita, S.E. Bursell, L.P. Aiello, F.W. Luscinskas, and A.P. Adamis Integrin-mediated neutrophil adhesion and retinal leukostasis in diabetes Invest. Ophthalmol. Vis. Sci. 41 2000 1153 1158
3. S.R. Bullard, D.L. Hatchell, H.J. Cohen, and K.M. Rao Increased adhesion of neutrophils to retinal vascular endothelial cells exposed to hyperosmolarity Exp. Eye. Res. 58 1994 641 647
4. M.B. Grisham, J.N. Benoit, and D.N. Granger Assessment of leukocyte involvement during ischemia and perfusion of intestine Methods Enzymol. 186 1990 729 741
5. F. Hirata, M. Yoshida, Y. Niwa, M. Okouchi, N. Okayama, Y. Takeuchi, M. Itoh, and Y. Ogura Insulin enhances leukocyte-endothelial cell adhesion in the retinal microcirculation through surface expression of intercellular adhesion molecule-1 Microvasc. Res. 69 2005 135 141
6. A.M. Joussen, T. Murata, A. Tsujikawa, B. Kirchhof, S.E. Bursell, and A.P. Adamis Leukocyte-mediated endothelial cell injury and death in the diabetic retina Am. J. Pathol. 158 2001 147 152
7. D. Koya, and G.L. King Protein kinase C activation and development of diabetic complications Diabetes 47 1998 859 866
8. T.A. Lane, G.E. Lamkin, and E. Wancewicz Modulation of endothelial cell expression of intercellular adhesion molecule-1 by protein kinase C activation Biochem Biophys Res Commun 161 1989 945 952
9. D.S. McLeod, D.J. Lefer, C. Merges, and G.A. Lutty Enhanced expression of intracellular adhesion molecule-1 and P-selectin in the diabetic retina and choroid Am. J. Pathol. 147 1995 642 653
10. K. Miyamoto, and Y. Ogura Pathogenetic potential of leukocytes in diabetic retinopathy Semin. Ophthalmol. 14 1999 233 239
11. K. Miyamoto, N. Hiroshiba, A. Tsujikawa, and Y. Ogura In vivo demonstration of increased leukocyte entrapment in retinal microcirculation of diabetic rats Invest. Ophthalmol. Vis. Sci. 39 1998 2190 2194
12. K. Miyamoto, S. Khosrof, S.E. Bursell, R. Rohan, T. Murata, A.C. Clermont, L.P. Aiello, Y. Ogura, and A.P. Adamis Prevention of leukostasis and vascular leakage in streptozotocin-induced diabetic retinopathy via intercellular adhesion molecule-1 inhibition Proc. Natl. Acad. Sci. USA 96 1999 10836 10841
13. M. Morigi, S. Angioletti, B. Imberti, R. Donadelli, G. Micheletti, M. Figliuzzi, A. Remuzzi, C. Zoja, and G. Remuzzi Leukocyte-endothelial interaction is augmented by high glucose concentrations and hyperglycemia in a NF-kB-dependent fashion J. Clin. Invest. 101 1998 1905 1915
14. A. Nonaka, J. Kiryu, A. Tsujikawa, K. Yamashiro, K. Miyamoto, H. Nishiwaki, Y. Honda, and Y. Ogura PKC-beta inhibitor (LY333531) attenuates entrapment in retinal microcirculation of diabetic rats Invest. Ophthalmol. Vis. Sci. 41 2000 2702 2706
15. M. Nozaki, Y. Ogura, Y. Hirabayashi, Y. Saishin, and S. Shimada Enhanced expression of adhesion molecules of the retinal vascular endothelium in spontaneous diabetic rats Ophthalmic. Res. 34 2002 158 164
16. M. Okouchi, N. Okayama, M. Shimizu, H. Omi, T. Fukutomi, and M. Itoh High insulin exacerbates neutrophil-endothelial cell adhesion through endothelial surface expression of intercellular adhesion molecule-1 via activation of protein kinase C and mitogen-activated protein kinase Diabetologia 45 2002 556 559
17. H. Omi, N. Okayama, M. Shimizu, M. Okouchi, S. Ito, T. Fukutomi, and M. Itoh Participation of high glucose concentrations in neutrophil adhesion and surface expression of adhesion molecules on cultured human endothelial cells: effect of antidiabetic medicines J. Diabetes Complications 16 2002 201 208
18. B. Wierusz-Wysocka, H. Wysocki, H. Siekierka, A. Wykretowicz, A. Szczepanik, and R. Klimas Evidence of polymorphonuclear neutrophils (PMN) activation in patients with insulin-dependent diabetes mellitus J. Leukoc. Biol. 42 1987 519 523