Linkage analysis of complex disease using microsatellites and single-nucleotide polymorphisms: Application to alcoholism

BMC Genetics

Volumn 6, Issue SUPPL.1, 2005, Pages

  Nsengimana, Jérémie ^a,b   Renard, Hélène ^a   Goldgar, David ^a  

^a INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

^b ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACCURACY; ALCOHOLISM; ARTICLE; CONTROLLED STUDY; GENE LINKAGE DISEQUILIBRIUM; GENE MAPPING; GENETIC ANALYSIS; GENOTYPE; HUMAN; LINKAGE ANALYSIS; MAJOR CLINICAL STUDY; MICROSATELLITE MARKER; NONPARAMETRIC TEST; PEDIGREE; SCORING SYSTEM; SIMULATION; SINGLE NUCLEOTIDE POLYMORPHISM; COMPUTER SIMULATION; GENETIC LINKAGE; GENETICS; HAPLOTYPE; QUANTITATIVE TRAIT;

MICROSATELLITE DNA;

ALCOHOLISM; COMPUTER SIMULATION; HAPLOTYPES; HUMANS; LINKAGE (GENETICS); MICROSATELLITE REPEATS; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT, HERITABLE; STATISTICS, NONPARAMETRIC;

EID: 30344462259     PISSN: None     EISSN: 14712156     Source Type: Journal    
DOI: 10.1186/1471-2156-6-S1-S10     Document Type: Article

References (9)

1. Reich T, Edenberg HJ, Goate A, Williams JT, Rice JP, Van Eerdewegh P, Foroud T, Hesselbrock V, Schuckit MA, Bucholz K, Porjesz B, Li TK, Conneally PM, Nurnberger JI Jr, Tischfield JA, Crowe RR, Cloninger CR, Wu W, Shears S, Carr K, Crose C, Willig C, Begleiter H: Genomewide search for genes affecting the risk for alcohol dependence. Am J Med Genet 1998, 81:207-215.
2. Almasy L, Borecki BI: Exploring genetic analysis of complex traits trough the paradigm of alcohol dependence: summary of GAW11 contributions. Genet Epidemiol 1999, 17(Suppl 1):S1-S24.
3. Kruglyak L, Daly MJ, Pat Reeve-Daly M, Lander ES: Parametric and non-parametric linkage analysis: a unified multipoint approach. Am J Hum Genet 1996, 58:1347-1363.
4. Sheffield LJ, Knauert MP, Pakstis AJ, Zhao H, Kidd KK: Analyses of the COGA data set in one ethnic group with examination of alternative definitions of alcoholism. Genet Epidemiol 1999, 17(Suppl 1):S319-S324.
5. Windemuth C, Hahn A, Strauch K, Baur MP, Weinker T: Linkage analysis in alcohol dependenc. Genet Epidemiol 1999, 17(Suppl 1):S403-S407.
6. Abecasis RG, Cherny SS, Cookson OW, Cardon RL: Merlin-rapid analysis of dense genetic maps using sparse gene flow trees. Nat Genet 2002, 30:97-101.
7. D'Alfonso S: Nonparametric linkage analysis of alcohol dependence with chromosome 4 and 7 markers. Genet Epidemiol 1999, 17(Suppl 1):S127-S131.
8. Barrett JC, Fry B, Maller J, Daly MJ: Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005, 21:263-265.
9. Gabriel SB, Schaffner SF, Nguyen H, Moore JM, Roy J, Blumenstiel B, Higgins J, DeFelice M, Lochner A, Faggart M, Liu-Cordero SN, Rotimi C, Adeyemo A, Cooper R, Ward R, Lander ES, Daly MJ, Atlshuler D: The structure of haplotype blocks in the human genome. Science 2002, 296:2225-2229.