Acute denervation alters the epithelial response to adrenoceptor activation through an increase in α 1-adrenoceptor expression on villus enterocytes

British Journal of Pharmacology

Volumn 147, Issue 1, 2006, Pages 101-108

  Baglole, Carolyn J ^a,b   Sigalet, David L ^a   Martin, Gary R ^a   Yao, Shengtao ^a   Meddings, Jon B ^a,c  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF ROCHESTER   (United States)

^c UNIVERSITY OF ALBERTA HOSPITAL   (Canada)

Author keywords

Adrenoceptors; Denervation; Enterocyte; Flow cytometry; Short circuit current; Small bowel transplantation

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 1 ADRENERGIC RECEPTOR STIMULATING AGENT; CHLORIDE; PHENYLEPHRINE;

ADRENERGIC SYSTEM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL FUNCTION; CONTROLLED STUDY; DENERVATION; EPITHELIUM CELL; FLOW CYTOMETRY; INTESTINE CELL; INTESTINE MUCOSA; INTESTINE SECRETION; INTESTINE TRANSPLANTATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RAT STRAIN; REDUCTION; SHORT CIRCUIT CURRENT; SYMPATHETIC INNERVATION;

ANIMALS; CELLS, CULTURED; DENERVATION; ENTEROCYTES; INTESTINAL MUCOSA; INTESTINE, SMALL; MALE; RATS; RATS, INBRED LEW; RECEPTORS, ADRENERGIC, ALPHA-1; SUCRASE;

EID: 30344461290     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706424     Document Type: Article

References (47)

1. AMEEN, N., ALEXIS, J. & SALAS, P. (2000). Cellular localization of the cystic fibrosis transmembrane conductance regulator in mouse intestinal tract. Histochem. Cell Biol., 114, 69-75.
2. BAGLOLE, C.J., DAVISON, J.S. & MEDDINGS, J.B. (2005). Epithelial distribution of neural receptors in the guinea pig small intestine. Can. J. Physiol. Pharmacol., 83, 389-395.
3. BALSIGER, B.M. & SARR, M.G. (2003). Chronic extrinsic denervation of the small bowel: effect on adrenergic and cholinergic contractile mechanisms in canine ileal circular muscle. Surgery, 134, 783-790.
4. BUTT, A.G., BOWLER, J.M. & MCLAUGHLIN, C.W. (1998). Villus and crypt cell composition in the secreting mouse jejunum measured with X-ray microanalysis. J. Membr. Biol., 162, 17-29.
5. CANADIAN COUNCIL ON CARE (1984). Guide to the Care and Use of Experimental Animals. Ottawa: Canadian Council on Animal Care.
6. CAREY, H.V. & ZAFIROVA, M. (1990). Adrenergic inhibition of neurally evoked secretion in ground squirrel intestine. Eur. J. Pharmacol., 181, 43-50.
7. CHANG, E.B., FEDORAK, R.N. & FIELD, M. (1986). Experimental diabetic diarrhea in rats. Intestinal mucosal denervation hypersensitivity and treatment with clonidine. Gastroenterology, 91, 564-569.
8. CHANG, E.B. & RAO, M.C. (1994). Intestinal water and electrolyte transport: mechanisms of physiological and adaptive responses. In: Physiology of the Gastrointestinal Tract. ed. Johnson, L.R., Alpers, D.H., Christensen, J., Jacobson, E.D. & Walsh, J.H. pp. 2027-2081. New York: Raven Press.
9. COOKE, H.J. & REDDIX, R.A. (1994). Neural regulation of intestinal electrolyte transport. In: Physiology of the Gasotrintestinal Tract. ed. Johnson, L.R., Alpers, D.H., Christensen, J., Jacobson, E.D. & Walsh, J.H. pp. 2083-2132. New York: Raven Press.
10. DAHLQVIST, A. (1964). Method for assay of intestinal disaccharidases. Anal. Biochem., 57, 18-25.
11. DELTZ, E., GEBHARDT, J.H., PREISSNER, C., SCHROEDER, P., HANSMANN, M.L., KAISERLING, E., MULLER-HERMELINK, H.K. & THIEDE, A. (1987). Distribution of gastrointestinal hormones in the adaptive response after small bowel transplantation. Gut., 28 (Suppl), 217-220.
12. - transport in rat small intestine. Pflugers Arch., 432, 293-300.
13. DONOWITZ, M. & MADARA, J.L. (1982). Effect of extracellular calcium depletion on epithelial structure and function in rabbit ileum: a model for selective crypt or villus epithelial cell damage and suggestion of secretion by villus epithelial cells. Gastroenterology, 83, 1231-1243.
14. EISENHOFER, G., ANEMAN, A., FRIBERG, P., HOOPER, D., FANDRIKS, L., LONROTH, H., HUNYADY, B. & MEZEY, E. (1997). Substantial production of dopamine in the human gastrointestinal tract. J. Clin. Endocrinol. Metab., 82, 3864-3871.
15. FIELD, M. & MCCOLL, I. (1973). Ion transport in rabbit ileal mucosa. 3. Effects of catecholamines. Am. J. Physiol., 225, 852-857.
16. FUKUDA, N., JAYR, C., LAZRAK, A., WANG, Y., LUCAS, R., MATALON, S. & MATTHAY, M.A. (2001). Mechanisms of TNF-alpha stimulation of amiloride-sensitive sodium transport across alveolar epithelium. Am. J. Physiol. Lung Cell Mol. Physiol., 280, L1258-L1265.
17. GRUBB, B.R. (1995). Ion transport across the jejunum in normal and cystic fibrosis mice. Am. J. Physiol., 268, G505-G513.
18. GUNTER-SMITH, P.J. & WHITE, J.F. (1979). Contribution of villus and intervillus epithelium to intestinal transmural potential difference and response to theophylline and sugar. Biochim. Biophys. Acta., 557, 425-435.
19. GYOMOREY, K., YEGER, H., ACKERLEY, C., GARAMI, E. & BEAR, C.E. (2000). Expression of the chloride channel ClC-2 in the murine small intestine epithelium. Am. J. Physiol. Cell. Physiol., 279, C1787-C1794.
20. HERKES, S.M., SMITH, C.D. & SARR, M.G. (1994). Jejunal responses to absorptive and secretory stimuli in the neurally isolated jejunum in vivo. Surgery, 116, 576-586.
21. HILDEBRAND, K.R. & BROWN, D.R. (1992). Norepinephrine and alpha-2 adrenoceptors modulate active ion transport in porcine small intestine. J. Pharmacol. Exp. Ther., 263, 510-519.
22. HILL, C.E., HIRST, G.D., NGU, M.C. & VAN HELDEN, D.F. (1985). Sympathetic postganglionic reinnervation of mesenteric arteries and enteric neurones of the ileum of the rat. J. Auton Nerv. Syst., 14, 317-334.
23. HIROKAWA, M., MIURA, S., SHIGEMATSU, T., YOSHIDA, H., HOKARI, R., HIGUCHI, H., KUROSE, I., KIMURA, H., SAITO, H., NAKAKI, T. & ISHII, H. (1997). Pressure stimulates proliferation and DNA synthesis in rat intestinal epithelial cells. Life Sci., 61, 667-672.
24. HUBEL, K.A. (1989). Control of intestinal secretion. In: Gastrointestinal Secretion. ed. Davison, J.S. pp. 178-201. London: Butterworth & Co.
25. KEAST, J.R., FURNESS, J.B. & COSTA, M. (1984). Origins of peptide and norepinephrine nerves in the mucosa of the guinea pig small intestine. Gastroenterology, 86, 637-644.
26. KENDRICK, M.L., MEILE, T., ZYROMSKI, N.J., TANAKA, T., LIBSCH, K.D. & SARR, M.G. (2002). Extrinsic denervation causes a transient proabsorptive adrenergic hypersensitivity in the canine proximal colon. Dig. Dis. Sci., 47, 1752-1757.
27. KENDRICK, M.L., MEILE, T., ZYROMSKI, N.J., TANAKA, T. & SARR, M.G. (2001). Extrinsic neural innervation mediates absorption of water and electrolytes in canine proximal colon in vivo. J. Surg. Res., 97, 76-80.
28. KIYOCHI, H., ONO, A., SHIMAHARA, Y. & KOBAYASHI, N. (1994). Extrinsic reinnervation after intestinal transplantation in rats. Transplant Proc., 26, 951-952.
29. LANG, M.E., DAVISON, J.S., BATES, S.L. & MEDDINGS, J.B. (1996). Opioid receptors on guinea-pig intestinal crypt epithelial cells. J. Physiol., 497 (Part 1), 161-174.
30. MOHAMMAD-PANAH, R., GYOMOREY, K., ROMMENS, J., CHOUDHURY, M., LI, C., WANG, Y. & BEAR, C.E. (2001). ClC-2 contributes to native chloride secretion by a human intestinal cell line, Caco-2. J. Biol. Chem., 276, 8306-8313.
31. MONTROSE, M.H., KEELY, S.J. & BARRETT, K.E. (1999). Electrolyte secretion and absorption: small intestine and colon. In: Textbook of Gastroenterology. ed. Yamada, T., Alpers, D.H., Laine, L., Owyang, C. & Powell, D.W. pp. 320-355. Philadelphia: Lippincott Williams & Wilkins Publishers.
32. OHTANI, N., BALSIGER, B.M., ANDING, W.J., DUENES, J.A. & SARR, M.G. (2000). Small bowel transplantation induces adrenergic hypersensitivity in ileal longitudinal smooth muscle in rats. J. Gastrointest. Surg., 4, 77-85.
33. OISHI, A.J. & SARR, M.G. (1995). Intestinal transplantation: effects on ileal enteric absorptive physiology. Surgery, 117, 545-553.
34. REID, J.L. & VINCENT, J. (1986). Clinical pharmacology and therapeutic role of prazosin and related alpha-adrenoceptor antagonists. Cardiology, 73, 164-174.
35. SHIBATA, C., BALSIGER, B.M., ANDING, W.J., DUENES, J.A., MILLER, V.M. & SARR, M.G. (1998). Functional changes in nonadrenergic, noncholinergic inhibitory neurons in ileal circular smooth muscle after small bowel transplantation in rats. Dig. Dis. Sci., 43, 2446-2454.
36. SHIBATA, C., BALSIGER, B.M., ANDING, W.J. & SARR, M.G. (1997). Adrenergic denervation hypersensitivity in ileal circular smooth muscle after small bowel transplantation in rats. Dig. Dis. Sci., 42, 2213-2221.
37. SIGALET, D.L., KNETEMAN, N.M., FEDORAK, R.N., KIZILISIK, A.T. & THOMSON, A.B. (1992a). Intestinal function following allogeneic small intestinal transplantation in the rat. Transplantation, 53, 264-271.
38. SIGALET, D.L., KNETEMAN, N.N., FEDORAK, R.N., KIZILISIK, T., MADSEN, K.E. & THOMSON, A.B. (1996). Small intestinal function following syngeneic transplantation in the rat. J. Surg. Res., 61, 379-384.
39. SIGALET, D., KNETEMAN, N.M. & THOMSON, A.B. (1992b). Small bowel transplantation: past, present and future. Dig. Dis., 10, 258-273.
40. STADELMANN, A.M., WALGENBACH-TELFORD, S., TELFORD, G.L. & KOCH, T.R. (1998). Distribution of muscarinic receptor subtypes in rat small intestine. J. Surg. Res., 80, 320-325.
41. STEWART, C.P. & TURNBERG, L.A. (1989). A microelectrode study of responses to secretagogues by epithelial cells on villus and crypt of rat small intestine. Am. J. Physiol., 257, G334-G343.
42. TRABER, P.G. (1999). Carbohydrate assimilation. In: Textbook of Gastroenterology. ed. Yamada, T., Alpers, D.H., Laine, L., Owyang, C. & Powell, D.W. pp. 404-428. Philadelphia: Lippincott Williams & Wilkins.
43. TSIOTOS, G.G., KENDRICK, M.L., LIBSCH, K., BIERENS, K., LANKISCH, P., DUENES, J.A. & SARR, M.G. (2001). Ileal absorptive adaptation to jejunal resection and extrinsic denervation: implications for living-related small bowel transplantation. J. Gastrointest. Surg., 5, 517-524.
44. VERGNOLLE, N., MACNAUGHTON, W.K., AL-ANI, B., SAIFEDDINE, M., WALLACE, J.L. & HOLLENBERG, M.D. (1998). Proteinase-activated receptor 2 (PAR2)-activating peptides: identification of a receptor distinct from PAR2 that regulates intestinal transport. Proc. Natl. Acad. Sci. U.S.A., 95, 7766-7771.
45. VIEIRA-COELHO, M.A. & SOARES-DA-SILVA, P. (1998). Alpha2-adrenoceptors mediate the effect of dopamine on adult rat jejunal electrolyte transport. Eur. J. Pharmacol., 356, 59-65.
46. WATSON, A.J., LEAR, P.A., MONTGOMERY, A., ELLIOTT, E., DACRE, J., FARTHING, M.J. & WOOD, R.F. (1988). Water, electrolyte, glucose, and glycine absorption in rat small intestinal transplants. Gastroenterology, 94, 863-869.
47. WEISER, M.M. (1973). Intestinal epithelial cell surface membrane glycoprotein synthesis. I. An indicator of cellular differentiation. J. Biol. Chem., 248, 2536-2541.