(E)-8-(3-Chlorostyryl)-1,3,7-trimethylxanthine, a caffeine derivative acting both as antagonist of adenosine A2A receptors and as inhibitor of MAO-B

Acta Crystallographica Section C: Crystal Structure Communications

Volumn 61, Issue 9, 2005, Pages

  Frédérick, Raphaël ^a   Ooms, Frederic ^a,f   Castagnoli Jr , Neal ^b   Petzer, Jacques P ^c   Feng, Jiang Fan ^d   Schwarzschild, Michael A ^d   Van Der Schyf, Cornells J ^c,e   Wouters, Johan ^a  

^a UNIVERSITY OF NAMUR   (Belgium)

^b VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

^c NORTH WEST UNIVERSITY   (South Africa)

^d HARVARD MEDICAL SCHOOL   (United States)

^e TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^f Euroscreen SA   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE RECEPTORS; PARALLEL STACKING; PHARMACOPHORE ELEMENTS;

CONFORMATIONS; DERIVATIVES; SULFUR COMPOUNDS;

CRYSTAL STRUCTURE;

8 (3 CHLOROSTYRYL) 1,3,7 TRIMETHYLXANTHINE; 8-(3-CHLOROSTYRYL)-1,3,7-TRIMETHYLXANTHINE; ADENOSINE A2 RECEPTOR ANTAGONIST; ADENOSINE A2A RECEPTOR; MONOAMINE OXIDASE INHIBITOR; XANTHINE DERIVATIVE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DRUG ANTAGONISM; ELECTRICITY; STATIC ELECTRICITY;

ADENOSINE A2 RECEPTOR ANTAGONISTS; ELECTROSTATICS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MONOAMINE OXIDASE INHIBITORS; RECEPTOR, ADENOSINE A2A; STATIC ELECTRICITY; XANTHINES;

EID: 30344455384     PISSN: 01082701     EISSN: None     Source Type: Journal    
DOI: 10.1107/S0108270105023140     Document Type: Article

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