Analgesic effects of aqueous extracts of the leaves of Bryophyllum pinnatum

Pharmaceutical Biology

Volumn 43, Issue 8, 2005, Pages 658-661

  Igwe, S A ^a   Akunyili, D N ^b  

^a EBONYI STATE UNIVERSITY TEACHING HOSPITAL   (Nigeria)

^b UNIVERSITY OF NIGERIA   (Nigeria)

Author keywords

Analgesia; Aqueous extract; Bryophyllum pinnatum; Potency; Shrub

Indexed keywords

ACETYLSALICYLIC ACID; ANALGESIC AGENT; BRYOPHYLLUM PINNATUM EXTRACT; NONSTEROID ANTIINFLAMMATORY AGENT; PHENYLQUINONE; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANALGESIA; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRYOPHYLLUM PINNATUM; CONTROLLED STUDY; CRASSULACEAE; DOSE RESPONSE; DRUG EFFICACY; DRUG POTENCY; DRUG SCREENING; FEMALE; HOT PLATE TEST; MALE; MOUSE; NONHUMAN; PAIN; PAIN THRESHOLD; PAW EDEMA; PLANT LEAF; RAT; TOXICITY TESTING; WRITHING TEST;

ANIMALIA; CRASSULACEAE; KALANCHOE PINNATA;

EID: 30344453618     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.1080/13880200500383108     Document Type: Article

References (11)

1. Beckett AN, Casy AF (1962): The testing and development of analgesic drugs. In: Ellis GP, ed., Progress in Medicine Chemistry, 2nd ed. London, Butterworth & Co., pp. 46-50.
2. Chau T, Walter T, Zimmerman J, Hartman D, Ochalski S, Weichman B. (1993): Analgesic activities of Pen-420, the active eutainer of Pumedolac. Agents Actions 39: C27-C29.
3. Covino BG, Dubner R, Gybeis J, Kosterlitz HW, Liebeskin C, Sternbach RA, Vyklicky L, Yamanura H, Zimmerman M (1980): Ethical standards for investigation of experimental pain in animals. Pain 9: 141-143.
4. Dalziel JM (1956): Useful plants of West Tropical Africa, 2nd ed. London, Crown Agents for Overseas Govts., pp. 26-29.
5. Dalziel JM, Hutchinston J (1958): Flora of West Tropical Africa, 2nd ed., Vol. I, part 1. London, Crown Agents for Overseas Governments and Administrations, p. 116.
6. Iwu MM (1982): Perspective of Igbo Tribal ethnomedicine, Vol. 2. Enugu, CECTA Nig. Ltd., p. 33.
7. Marini-Bettolo GB, Nicoletti M, Patamia M, Geleffi C, Messana I (1981). Plant screening by chemical and chromatographic procedures under field conditions. J Chromatogr 213: 113-127.
8. Otterness IG, Bliven ML (1985): Laboratory models for testing nonsteroidal anti-inflammatory drugs. In: Lombardino JG, ed., NSAID. New York, John Wiley & Sons, pp. 111-252.
9. Siegmund E, Cadmus R, Lu G. (1957): A method for evaluating both non-narcotic and narcotic analgesics. Proc Soc Exp Biol Med 95: 729-731.
10. Woolfe G, MacDonald AD (1964): Hot plate for assessing analgesic effects. J Pharmacol Exp Ther 80: 300-307.
11. Zimmerman M (1983): Ethical guidelines for investigation of experimental pain in conscious animals. Pain 16: 109-110.