Amantadine to enhance readiness for rehabilitation following severe traumatic brain injury

Brain Injury

Volumn 19, Issue 14, 2005, Pages 1197-1206

  Hughes, Shari ^a   Colantonio, Angela ^b   Santaguida, P Lina ^c   Paton, Thomas ^a  

^a SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c MCMASTER UNIVERSITY   (Canada)

Author keywords

Amantadine; Brain injury; Coma; Recovery

Indexed keywords

AMANTADINE; ANTIBIOTIC AGENT;

ADOLESCENT; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; COHORT ANALYSIS; COMA; CONSCIOUSNESS; CONVALESCENCE; DISEASE DURATION; DRUG COST; DRUG SAFETY; EVOKED SOMATOSENSORY RESPONSE; FEMALE; GLASGOW COMA SCALE; HUMAN; INJURY SEVERITY; LENGTH OF STAY; MALE; PREDICTION; RETROSPECTIVE STUDY; SIDE EFFECT; STATISTICAL ANALYSIS; TRAUMATIC BRAIN INJURY;

EID: 30344447710     PISSN: 0883041X     EISSN: 1362301X     Source Type: Journal    
DOI: 10.1080/02699050500309296     Document Type: Article

References (67)

1. Bricolo, A and Turazzi, S and Feriotti, G. (1980) Prolonged posttraumatic unconsciousness: Therapeutic assets and liabilities Journal of Neurosurgery, 52, pp. 625 - 634.
2. Lyle, DM and Pierce, JP and Freeman, EA. (1986) Clinical course and outcome of severe head injury in Australia Journal of Neurosurgery, 65, pp. 15 - 18. et al.
3. (1994) Multi-Society Task Force on Persistent Vegetative State. Medical aspects of the persistent vegetative state New England Journal of Medicine, 330, pp. 1572 - 1579.
4. Hagen, C and Malkmus, D and Durham, P.(1979) Levels of cognitive functioning. In In: Rehabilitation of the head-injured adult: Comprehensive management. Downey CA: Professional Staff Association of Ranchos Los Amigos Hospital.
5. Ansell, BJ and Keenan, JE. (1989) The Western neuro sensory stimulation profile: A tool for assessing slow-to-recover head-injured patients Archives of Physical Medicine and Rehabilitation, 70, pp. 104 - 108.
6. Ansell, BJ. (1993) Slow to recover patients: Improvement to rehabilitation readiness Journal of Head Trauma Rehabilitation, 8, pp. 88 - 98.
7. Patrick, PD and Buck, ML and Conaway, MR. (2003) The use of dopamine enhancing medications with children in low response states following brain injury Brain Injury, 17, pp. 497 - 506. et al.
8. Waxman, K and Sundine, MJ and Young, RF. (1991) Is early prediction of outcome in severe head injury possible? Archives of Surgery, 126, pp. 1237 - 1241.
9. Braakman, R and Gelpke, GJ and Habbema, JD. (1980) Systematic selection of prognostic features in patients with severe head injury Neurosurgery, 64, pp. 362 - 370. et al.
10. Hans, P and Albert, A and Born, JD. (1987) Predicting recovery from head injury British Journal of Hospital Medicine, 37, pp. 535, 538 - 540.
11. Choi, SC and Narayan, RK and Anderson, RL. (1988) Enhanced specificity of prognosis in severe head injury Journal of Neurosurgery, 69, pp. 381 - 385. et al.
12. Jaggi, JL and Obrist, WD and Gennarelli, TA. (1990) Relationship of early cerebral blood flow and metabolism to outcome in acute head injury Journal of Neurosurgery, 72, pp. 176 - 182. et al.
13. Marmarou, A and Anderson, RL and Ward, JD. (1991) Impact of ICP instability and hypotension on outcome in patients with severe head trauma Journal of Neurosurgery, 75, pp. S59 - S66. et al
14. Rudnick, A and Wojtacha, M and Wencel, T. (1992) The prognostic value of some clinical and diagnostic factors in traumatic intracranial hematoma (Suppl) Acta Neurochirurgical, 55, pp. 33 - 36. et al.
15. Fearnside, MR and Cook, RJ and McDougall, P. (1993) The Westmead head injury project: Outcome in severe head injury. A comparative analysis of pre-hospital, clinical and CT variables British Journal of Neurosurgery, 7, pp. 267 - 279. et al.
16. Beca, J and Cox, PN and Taylor, MJ. (1995) Somatosensory evoked potentials for prediction of outcome in acute severe brain injury Journal of Pediatrics, 126, pp. 44 - 49. et al.
17. Combes, P and Fauvage, B and Colonna, M. (1996) Severe head injuries: On outcome prediction and survival analysis Intensive Care Medicine, 22, pp. 1391 - 1395. et al.
18. Koc, RK and Akdemir, H and Oktem, IS. (1997) Acute subdural hematoma: Outcome and outcome prediction Neurosurgical Review, 20, pp. 239 - 244. et al.
19. Pohlmann-Eden, B and Dingethal, K and Bender, HJ. (1997) How reliable is the predictive value of SEP (somatosensory evoked potentials) patterns in severe brain damage with special regard to bilateral loss of cortical responses? Intensive Care Medicine, 23, pp. 301 - 308. et al.
20. Quigley, MR and Vidovich, D and Cantella, D. (1997) Defining the limits of survivorship after very severe head injury Journal of Trauma-Injury Infection & Critical Care, 42, pp. 7 - 10. et al.
21. Kampfl, A and Schmutzhard, E and Franz, G. (1998) Prediction of recovery from post-traumatic vegetative state with cerebral magnetic resonance imaging Lancet, 351, pp. 1763 - 1767. et al.
22. Carter, BG and Taylor, A and Butt, W. (1999) Severe brain injury in children: Long-term outcome and its prediction using somatosensory evoked potentials (SEPs) Intensive Care Medicine, 25, pp. 722 - 728.
23. Signorini, DF and Andrews, PJ and Jones, PA. (1999) Predicting survival using simple clinical variables: A case study in traumatic brain injury Journal of Neurology, Neurosurgery & Psychiatry, 66, pp. 20 - 25. et al.
24. Signorini, DF and Andrews, PJ and Jones, PA. (1999) Adding insult to injury: The prognostic value of early secondary results for survival after traumatic brain injury Journal of Neurology, Neurosurgery & Psychiatry, 66, pp. 26 - 31. et al.
25. Houlden, DA and Chen Li, RA and Schwartz, ML. (1990) Median nerve somatosensory evoked potentials and the Glasgow Coma Scale as predictors of outcome in comatose patients with head injuries Neurosurgery, 27, pp. 701 - 707. et al.
26. Baker, SP and O'Neill, B and Haddon, W. (1974) The injury severity score: A method for describing patients with multiple injuries and evaluating emergency care Journal of Trauma - Injury, Infection & Critical Care, 14, pp. 187 - 196. et al.
27. Cope, DN. (1995) The effectiveness of traumatic brain injury rehabilitation: A review Brain Injury, 9, pp. 649 - 670.
28. Hall, KM and Cope, DN. (1995) The benefit of rehabilitation in traumatic brain injury: A literature review Journal of Head Trauma Rehabilitation, 10, pp. 1 - 13.
29. Cope, DN and Hall, K. (1982) Head injury rehabilitation: Benefit of early intervention Archives of Physical Medicine and Rehabilitation, 63, pp. 433 - 437.
30. Malec, JF and Basford, JS. (1996) Post-acute brain injury rehabilitation Archives of Physical Medicine and Rehabilitation, 77, pp. 198 - 207.
31. Davis, CW and Kerrick, RC. (1985) Treatment of head injured patients in the acute stages Clinical Management in Physical Therapy, 5, pp. 16 - 18. 20-21, 23
32. Edwards, SM. (1987) Comprehensive treatment programs for severely disabled brain injured patients Clinical Management in Physical Therapy, 7, pp. 6 - 10.
33. Giacino, JT and Zasler, ND and Katz, DI. (1997) Development of practice guidelines for assessment and management of the vegetative and minimally conscious states Journal of Head Trauma Rehabilitation, 12, pp. 79 - 89. et al.
34. Hall, M and Brandys, C and Yetman, L. (1992) Multi-disciplinary approaches to management of acute head injury Journal of Neuroscience Nursing, 24, pp. 199 - 204.
35. Gladstone, DJ and Black, SE. (2000) Enhancing recovery after stroke with noradrenergic pharmacotherapy: A new frontier? Canadian Journal of Neurological Sciences, 27, pp. 97 - 105.
36. Phillips, JP and Devier, DJ and Feeney, DM. (2003) Rehabilitation pharmacology: Bridging laboratory work to clinical application Journal of Head Trauma Rehabilitation, 18, pp. 342 - 356.
37. Whyte, J. (1992) Attention and arousal: Basic science aspects Archives of Physical Medicine and Rehabilitation, 73, pp. 940 - 949.
38. Reinhard, DL and Whyte, J and Sandel, ME. (1996) Improved arousal and initiation following tricyclic antidepressant use in severe brain injury Archives of Physical Medicine and Rehabilitation, 77, pp. 80 - 83.
39. Chen, HV and Pellegrini, JW and Aggarwal, SK. (1992) Open-channel block of N-methyl-D-aspartate (NMDA) responses by Memantine: Therapeutic advantage against NMDA receptor- mediated neurotoxicity Journal of Neuroscience, 12, pp. 4427 - 4436. et al.
40. McIntosh, TK and Juhler, M and Wieloch, T. (1998) Novel pharmacologic strategies in the treatment of experimental traumatic brain injury: 1998 Journal of Neurotrauma, 15, pp. 731 - 769.
41. Stover, JF and Morganti-Kosmann, MC and Lenzlinger, PM. (1999) Glutamate and taurinease increased in ventricular CSF of severely brain injured Journal of Neurotrauma, 16, pp. 135 - 142. et al.
42. Yamamoto, T and Rossi, S and Stiefel, M. (1999) CSF and ECF glutamate concentrations in head injured patients Acta Neurochirurgica - Supplementum, 75, pp. 17 - 19. et al.
43. Nickels, JK and Schneider, WN and Dombovy, ML. (1994) Clinical use of amantadine in brain injury rehabilitation Brain Injury, 8, pp. 709 - 718. et al.
44. Aoki, FY and Sitar, DS. (1988) Clinical pharmacokinetics of amantadine hydrochloride Clinical Pharmacokinetics, 14, pp. 35 - 51.
45. Cowell, LC and Cohen, RF. (1995) Amantadine: A potential adjuvant therapy following traumatic brain injury Journal of Head Trauma Rehabilitation, 10, pp. 91 - 94.
46. Edby, K and Larsson, J and Eek, M. (1983) Amantadine treatment of a patient with anoxic brain injury Child's Nervous System, 11, pp. 607 - 609. et al.
47. Gualtieri, T and Chandler, M and Coons, TB. (1989) Amantadine: A new clinical profile for traumatic brain injury Clinical Neuropharmacology, 12, pp. 258 - 270. et al.
48. Kraus, MF and Maki, PM. (1997) Effect of amantadine hydrochloride on symptoms of frontal lobe dysfunction in brain injury: Case studies and review Journal of Neuropsychiatry and Clinical Neurosciences, 9, pp. 222 - 230.
49. van Reekum, R and Bayley, M and Garner, S. (1995) N of 1 study: Amantadine for the amotivational syndrome in a patient with traumatic brain injury Brain Injury, 9, pp. 49 - 53. et al.
50. Schwab, RS and England, AC and Pokanzer, DC. (1969) Amantadine and the treatment of Parkinson's disease Journal of the American Medical Association, 208, pp. 1168 - 1170. et al.
51. Verhagen Metman, L and Del Dotto, P and Nad den Munchkhof, P. (1998) Amantadine as treatment for dyskinesias and motor fluctuations in Parkinson's disease Neurology, 50, pp. 1323 - 1326. et al.
52. Chandler, MC and Barnhill, JT and Gualtieri, CT. (1988) Amantadine for the agitated head injury patient Brain Injury, 2, pp. 309 - 311.
53. Kraus, MF and Maki, PM. (1997) The combined use of amantadine and l-dopa/ carbidopa in the treatment of chronic brain injury Brain Injury, 11, pp. 455 - 460.
54. Schneider, WN and Drew-Cates, J and Wong, TM.Cognitive and behavioural efficacy of amantadine in acute traumatic brain injury: An initial double blind, placebo-controlled study Brain Injury, 13, pp. 863 - 872. et al.
55. Shiller, AD and Burke, DT and Kim, HJ. (1999) Treatment with amantadine potentiated motor learning in a patient with traumatic brain injury of 15 years' duration Brain Injury, 13, pp. 715 - 721. et al.
56. Karli, DC and Burke, DT and Kim, HJ. (1999) Effects of dopaminergic combination therapy for frontal lobe dysfunction in traumatic brain injury rehabilitation Brain Injury, 13, pp. 63 - 68. et al.
57. Raffaele, R and Nicoletti, G and Vecchio, I. (2002) Use of amantadine in the treatment of the neurobehavioral sequelae after brain injury in elderly patients Archives of Gerontology and Geriatrics, Suppl. 8, pp. 309 - 312. et al.
58. Patrick, PD and Patrick, ST and Poole, JD. (2000) Evaluation and treatment of the vegetative and minimally conscious child: A single subject design Behavioral Interventions, 15, pp. 225 - 242. et al.
59. Zafonte, RD and Watanabe, T and Mann, NR. (1998) Amantadine: A potential treatment for the minimally conscious state Brain Injury, 12, pp. 617-621.
60. Meythaler, JM and Brunner, RC and Johnson, A. (2003) Amantadine to improve neurorecovery in traumatic brain injury-associated diffuse axonal injury: A pilot double blind randomized trial Journal of Head Trauma Rehabilitation, 17, pp. 300 - 313. et al.
61. McIntosh, TK. (1993) Novel pharmacologic therapies in the treatment of experimental traumatic brain injury: A review Journal of Neurotrauma, 10, pp. 215 - 234.
62. Bassetti, C and Bomio, F and Mathis, J. (1996) Early prognosis in coma after cardiac arrest: A prospective clinical, electrophysiological and biochemical study of 60 patients Journal of Neurology, Neuroscience & Psychiatry, 61, pp. 610 - 615. et al.
63. Goldberg, G and Karazim, E. (1998) Application of evoked potentials to the prediction of discharge status in minimally responsive patients: A pilot study Journal of Head Trauma Rehabilitation, 13, pp. 51 - 68.
64. Andrews, K. (1996) International working party on the management of the vegetative state: Summary report Brain Injury, 10, pp. 797 - 806.
65. Giacino, JT and Zasler, ND. (1995) Outcome after severe traumatic brain injury: Coma, the vegetative state and the minimally responsive state Journal of Head Trauma Rehabilitation, 10, pp. 40 - 56.
66. Rosner, B.(1995) Fundamentals of biostatistics. Toronto: Duxbury Press.
67. Whyte, J and Katz, D and Long, D. (2005) Predictors of outcome in prolonged posttraumatic disorders of consciousness and assessment of medication effects: A multi-center study Archives of Physical Medicine and Rehabilitation, 86, pp. 453 - 462. et al.