Crystal structure of a heterodimer of phospholipase A2 from Naja naja sagittifera at 2.3 Å resolution reveals the presence of a new PLA 2-like protein with a novel Cys 32-Cys 49 disulphide bridge with a bound sugar at the substrate-binding site

Proteins: Structure, Function and Genetics

Volumn 62, Issue 2, 2006, Pages 329-337

  Jabeen, Talat ^a   Singh, Nagendra ^a   Singh, Rajendra K ^a   Jasti, Jayasankar ^a   Sharma, Sujata ^a   Kaur, Punit ^a   Srinivasan, Alagiri ^a   Singh, Tej P ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Crystal structure; Cys PLA2; Heterodimer; PLA2; Sequence determination; X ray diffraction

Indexed keywords

CARBOHYDRATE; COORDINATION COMPOUND; CYSTEINE; DIMER; MONOMER; N ACETYLGLUCOSAMINE; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 LIKE PROTEIN; SNAKE VENOM; SOLVENT; UNCLASSIFIED DRUG; ZINC ION;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; CRYSTAL STRUCTURE; DIMERIZATION; ELECTRON; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; HYDROGEN BOND; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; NAJA NAJA SAGITTIFERA; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FOLDING; SNAKE; SURFACE PROPERTY; VAN DER WAALS INTERACTION;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; COBRA; COBRA VENOMS; CRYSTALLOGRAPHY, X-RAY; CYSTEINE; DIMERIZATION; DISULFIDES; DNA, COMPLEMENTARY; LIGHT; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; PHOSPHOLIPASES A; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; SCATTERING, RADIATION;

ANIMALIA; NAJA SAGITTIFERA;

EID: 30144443653     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/prot.20708     Document Type: Article

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