High-resolution intravital NADH fluorescence microscopy allows measurements of tissue bioenergetics in rat ileal mucosa

Microcirculation

Volumn 13, Issue 1, 2006, Pages 41-47

  Rose, Jim ^a,b   Martin, Claudio ^a,b   MacDonald, Tammy ^a,b   Ellis, Chris ^a,b  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b LONDON HEALTH SCIENCES CENTRE   (Canada)

Author keywords

Bowel mucosa; Microcirculation; Mitochondrial; Oxygenation

Indexed keywords

ISOFLURANE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOENERGY; CONTROLLED STUDY; EX VIVO STUDY; FLUORESCENCE MICROSCOPY; ILEUM MUCOSA; IN VIVO STUDY; INTESTINE BLOOD FLOW; INTESTINE ISCHEMIA; MALE; NONHUMAN; PH; PRIORITY JOURNAL; RAT; RAT STRAIN; RELIABILITY;

ANIMALS; ENERGY METABOLISM; HYDROGEN-ION CONCENTRATION; ILEUM; INTESTINAL MUCOSA; ISCHEMIA; MALE; MICROSCOPY, FLUORESCENCE; MICROSCOPY, VIDEO; NAD; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA;

EID: 30144431856     PISSN: 10739688     EISSN: 15498719     Source Type: Journal    
DOI: 10.1080/10739680500383472     Document Type: Article

References (22)

1. Antonsson, J and Boyle, C and Kruithoff, K and Wang, H and Sacristan, E and Rothschild, H and Fink, M. (1990) Validation of tonometric measurement of gut intramural pH during endotoxemia and mesenteric occlusion in pigs Am J Physiol, 259, pp. G519-G523. [PUBMED] [INFOTRIEVE] [CSA]
2. Baum, T and Wang, H and Rothschild, H and Gang, D and Fink, M. (1990) Mesenteric oxygen metabolism, ileal mucosal hydrogen ion concentration, and tissue edema after crystalloid or colloid resuscitation in porcine endotoxic shock: Comparison of Ringer's lactate and 6% hetastarch Circ Shock, 30, pp. 385-397. [PUBMED] [INFOTRIEVE] [CSA]
3. Cicutti, N and Rakusan, K and Downey, H. (1994) Coronary artery occlusion extends perfusion territory boundaries through microvascular collaterals Basic Res Cardiol, 89, pp. 427-437. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
4. Coremans, J and Ince, C and Bruining, H and Puppels, G. (1997) (Semi-) Quantitative analysis of reduced nicotinamide adenine dinucleotide fluorescence images of blood-perfused rat heart Biophys J, 72, pp. 1849-1860. [PUBMED] [INFOTRIEVE] [CSA]
5. Duboc, D and Abastado, P and Muffat-Joly, M and Perrier, P and Toussaint, M and Marsac, C and Francois, D and Lavergne, T and Pocidalo, J and Guerin, F and Carpentier, A. (1990) Evidence of mitochondrial impairment during cardiac allograft rejection Transplantation, 50, pp. 751-755. [PUBMED] [INFOTRIEVE] [CSA]
6. Farquhar, I and Martin, C and Lam, C and Potter, R and Ellis, C and Sibbald, W. (1996) Decreased capillary density in vivo in bowel mucosa of rats with normotensive sepsis J Surg Res, 61, pp. 190-196. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
7. Fink, M. (1997) Cytopathic hypoxia: Mitohondrial dysfunction as a potential mechanism contributing to organ failure in sepsis Acta Anaesthesiol Scand Suppl, 110, pp. 87-95. [PUBMED] [INFOTRIEVE] [CSA]
8. Golub, A and Popel, A and Zheng, L and Pittman, R. (1999) Analysis of phosphorescence decay for nonuniform oxygen tension: Consequences of finite excitation flash duration Adv Exp Med Biol, 471, pp. 649-659. [PUBMED] [INFOTRIEVE] [CSA]
9. Ince, C and Ashruf, J and Sanderse, E and Pierik, E and Coremans, J and Bruining, H. (1992) In vivo NADH and Pd-porphyrin video fluori-/ phosphorimetry Adv Exp Med Biol, 317, pp. 267-275. [PUBMED] [INFOTRIEVE] [CSA]
10. Ince, C and Coremans, J and Bruining, H. (1992) In vivo NADH fluorescence Adv Exp Med Biol, 317, pp. 277-296. [PUBMED] [INFOTRIEVE] [CSA]
11. Ince, C and Vink, H and Wieringa, P and Giezeman, M and Spaan, J. (1990) Heterogeneous NADH fluorescence during post-anoxic reactive hyperemia in saline perfused rat heart Adv Exp Med Biol, 277, pp. 477-482. [PUBMED] [INFOTRIEVE] [CSA]
12. Jobsis, F and Duffield, J. (1967) Oxidative and glycolytic recovery metabolism in muscle: Fluorometric observations on their relative contributions J Gen Physiol, 50, pp. 1009-1047. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
13. Kampp, M and Lundgren, O and Nilsson, N. (1968) Extravascular shunting of oxygen in the small intestine of the cat Acta Physiol Scand, 72, pp. 396-403. [PUBMED] [INFOTRIEVE] [CSA]
14. Kelly, J and Rorvick, D and Richmond, K and Barlow, C. (1989) Videofluorometer for imaging tissue metabolism Rev Sci Instrum, 60, pp. 3498-3502. [CROSSREF] [CSA]
15. Menger, M and Vollmar, B. (1996) In vivo documentation of an arteriovenous shunt in rat pancreatic acinar tissue Pancreas, 13, pp. 125-129. [PUBMED] [INFOTRIEVE] [CSA]
16. Nuutinen, E. (1984) Subcellular origin of the surface fluorescence of reduced nicotinamide nucleotides in the isolated perfused rat heart Basic Res Cardiol, 79, pp. 49-58. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
17. Rose, J and Pitt-Hyde, M and Martin, C. (2001) Cellular dysoxia exists in the villus tips of rats with normotensive sepsis Crit Care Med, 29(12 Suppl), pp. A26. (Abstr) [CSA]
18. Temmesfeld-Wollbruck, B and Mayer, K and Grimminger, F. (2000) Assessment of intestinal tissue oxygenation: The canary sings - But what does the twitter tell us? Intensive Care Med, 26, pp. 1025-1027. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
19. Temmesfled-Wollbruck, B and Szalay, A and Olschewski, H and Grimminger, F and Seeger, W. (1997) Advantage of buffered solutions or automated capnometry in air-filled balloons for use in gastric tonometry Intensive Care Med, 23, pp. 423-427. [CROSSREF] [CSA]
20. Tugtekin, I and Radermacher, P and Theisen, M and Matejovic, M and Stehr, A and Ploner, F and Matura, K and Ince, C and Georgieff, M and Trager, K. (2001) Increased ileal mucosal arterial PCO2 gap is associated with impaired villus microcirculation in endotoxemic pigs Intensive Care Med, 27, pp. 757-766. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
21. Vollmar, B and Burkhardt, M and Minor, T and Klauke, H and Menger, M. (1997) Technical report: High-resolution microscopic assessment of hepatic NADH fluorescence for in vivo monitoring of tissue oxygenation during hemorrhagic shock and resuscitation Microvasc Res, 54, pp. 164-173. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
22. Wakita, M and Nishimura, G and Tamura, M. (1995) Some characteristics of the fluorescence lifetime of reduced pyridine nucleotides in isolated mitochondria, isolated hepatocytes, and perfused rat liver in situ J Biochem (Tokyo), 18, pp. 1151-1160. [CSA]