Edaravone inhibits rheumatoid synovial cell proliferation and migration

Free Radical Research

Volumn 40, Issue 2, 2006, Pages 121-125

  Arii, Kaoru ^a   Kumon, Yoshitaka ^a   Ikeda, Yukio ^a   Suehiro, Tadashi ^a   Hashimoto, Kozo ^a  

^a KOCHI UNIVERSITY   (Japan)

Author keywords

Free radical; Migration; Oxidative stress; Proliferation; Rheumatoid arthritis; Synovial cell

Indexed keywords

CYTOKINE; INTERLEUKIN 1BETA; NORPHENAZONE; SCAVENGER;

AGED; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN INFARCTION; CASE REPORT; CELL MIGRATION; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; FEMALE; GENE FUNCTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; JAPAN; JOINT DESTRUCTION; OXIDATIVE STRESS; RHEUMATOID ARTHRITIS; SYNOVIOCYTE;

AGED; ANTIPYRINE; ARTHRITIS, RHEUMATOID; CELL MOVEMENT; CELL PROLIFERATION; FEMALE; FREE RADICAL SCAVENGERS; HUMANS; INTERLEUKIN-1; SYNOVIAL MEMBRANE;

EID: 30144431539     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.1080/10715760500401116     Document Type: Article

References (24)

1. Cimen, MY and Cimen, OB and Kacmaz, M and Ozturk, HS and Yorgancioglu, R and Durak, I. (2000) Oxidant/antioxidant status of the erythrocytes from patients with rheumatoid arthritis Clin Rheumatol, 19, pp. 275-277.
2. Ozturk, HS and Cimen, MY and Cimen, OB and Kacmaz, M and Durak, I. (1999) Oxidant/antioxidant status of plasma samples from patients with rheumatoid arthritis Rheumatol Int, 19, pp. 35-37.
3. Firestein, GS and Yeo, M and Zvaifler, NJ. (1995) Apoptosis in rheumatoid arthritis synovium J Clin Invest, 96, pp. 1631-1638.
4. Winrow, VR and Winyard, PG and Morris, CJ and Blake, DR. (1993) Free radicals in inflammation: Second messengers and mediators of tissue destruction Br Med Bull, 49, pp. 506-522.
5. Giuseppe, MC and Angela, A and Salvatore, C and Alida, MF and Domenica, A and Alberto, C. (2003) Efficacy of treatment with glycosaminoglycans on experimental collagen-induced arthritis in rats Arthritis Res Ther, 5, pp. R122-R131.
6. Edaravone Acute Infarction Study Group. (2003) Effect of a novel free radical scavenger, edaravone (MCI-186), on acute brain infarction. Randomized, placebo-controlled, double-blind study at multicenters Cerebrovasc Dis, 15, pp. 222-229.
7. Shinji, A and Kazuyoshi, K and Koichiro, T and Masumi, O and Toyoshi, H and Hitoshi, H and Masanori, Y and Toshiaki, T. (2004) The reaction rate of Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one (MCI-186)) with hydroxyl radical Chem Pharm Bull, 52, pp. 186-191.
8. Satoh, M and Kashihara, N and Fujimoto, S and Horike, H and Tokura, T and Namikoshi, T and Sasaki, T and Makino, H. (2003) A novel free radical scavenger, Edarabone, protects against cisplatin-induced acute renal damage in vitro and in vivo J Pharmacol Exp Ther, 305, pp. 1183-1190.
9. Tada, S and Nakamoto, N and Kameyama, K and Tsunematsu, S and Kumagai, N and Saito, H and Ishii, H. (2003) Clinical usefulness of edaravone for acute liver injury J Gastroenterol Hepatol, 18, pp. 851-857.
10. Araki, Y and Andoh, A and Fujiyama, Y. (2003) The free radical scavenger edaravone suppresses experimental dextran sulfate sodium-induced colitis in rats Int J Mol Med, 12, pp. 125-129.
11. Araki, Y and Andoh, A and Yokono, T and Asano, N and Yoshikawa, K and Bamba, S and Ishizuka, I and Fujiyama, Y. (2003) The free radical scavenger edaravone suppresses experimental closed duodenal loop-induced acute pancreatitis in rats Int J Mol Med, 12, pp. 121-124.
12. Saibara, T and Toda, K and Wakatsuki, A and Ogawa, Y and Ono, M and Onishi, S. (2003) Protective effect 3-methyl-1-phenyl-2-pyrazolin-5-one, a free radical scavenger, on acute toxicity of paraquat in mice Toxicol Lett, 143, pp. 51-54.
13. Kumon, Y and Suehiro, T and Hashimoto, K and Nakatani, K and Sipe, JD. (1999) Local expression of acute-phase serum amyloid A (A-SAA) mRNA in rheumatoid arthritis synovial tissue and cells J Rheumatol, 26, pp. 785-790.
14. Trillo-Pazos, G and McFarlane-Abdulla, E and Campbell, IC and Pilkington, GJ and Everall, IP. (2000) Recombinant nef HIV-IIIB protein is toxic to human neurons in culture Brain Res, 864, pp. 315-326.
15. Bursztajn, S and Feng, JJ and Berman, SA and Nanda, A. (2000) Poly (ADP-ribose) polymerase induction is an early signal of apoptosis in human neuroblastoma Brain Res Mol Brain Res, 76, pp. 363-376.
16. Yamamoto, O and Hamada, T and Tokui, N and Sasaguri, Y. (2001) Comparison of three in vitro assay systems used for assessing cytotoxic effect of heavy metals on cultured human keratinocytes J UOEH, 23, pp. 35-44.
17. Okamoto, O and Fujiwara, S and Abe, M and Sato, Y. (1999) Dermatopontin interacts with transforming growth factor beta and enhances its biological activity Biochem J, 337, pp. 537-541.
18. Kumon, Y and Hosokawa, T and Suehiro, T and Ikeda, Y and Sipe, JD and Hashimoto, K. (2002) Acute-phase, but not constitutive serum amyloid A (SAA) is chemotactic for cultured human aortic smooth muscle cells Amyloid, 9, pp. 237-241.
19. Thabrew, MI and Senaratna, L and Samarawickrema, N and Munasinghe, C. (2001) Antioxidant potential of two polyherbal preparations used in ayurveda for the treatment of rheumatoid arthritis J Ethnopharmacol, 76, pp. 285-291.
20. Aaseth, J and Haugen, M and Forre, O. (1998) Rheumatoid arthritis and metal compounds-perspectives on the role of oxygen radical detoxification Analyst, 123, pp. 3-6.
21. Cerhan, JR and Saag, KG and Merlino, LA and Mikuls, TR and Criswell, LA. (2003) Antioxidant micronutrients and risk of rheumatoid arthritis in a cohort of older women Am J Epidemiol, 157, pp. 345-354.
22. Criswell, LA and Merlino, LA and Cerhan, JR and Mikuls, TR and Mudano, AS and Burma, M and Folsom, AR and Saag, KG. (2002) Cigarette smoking and the risk of rheumatoid arthritis among postmenopausal women: Results from the Iowa Women's Health Study Am J Med, 112, pp. 465-471.
23. Lipsky, PE and van der Heijde, DM and St Clair, EW and Furst, DE and Breedveld, FC and Kalden, JR and Smolen, JS and Weisman, M and Emery, P and Feldmann, M and Harriman, GR and Maini, RN. (2000) Anti-tumor necrosis factor trial in rheumatoid arthritis with concomitant therapy study group. Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-tumor necrosis factor trial in rheumatoid arthritis with concomitant therapy study group N Engl J Med, 343, pp. 1594-1602.
24. Klareskog, L and van der Heijde, D and de Jager, JP and Gough, A and Kalden, J and Malaise, M and Martin Mola, E and Pavelka, K and Sany, J and Settas, L and Wajdula, J and Pedersen, R and Fatenejad, S and Sanda, M. (2004) TEMPO (trial of etanercept and methotrexate with radiographic patient outcomes) study investigators. Therapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid arthritis: Double-blind randomized controlled trial Lancet, 363, pp. 675-681.