Distinct localizations and repression activities of MM-1 isoforms toward c-Myc

Journal of Cellular Biochemistry

Volumn 97, Issue 1, 2006, Pages 145-155

  Hagio, Yuko ^a   Kimura, Yumiko ^a   Taira, Takahiro ^a,b   Fujioka, Yuko ^a   Iguchi Ariga, Sanae M M ^a,b   Ariga, Hiroyoshi ^a,b  

^a HOKKAIDO UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

c Myc; MM 1; Splicing isoform; Transrepression

Indexed keywords

AMINO ACID; BINDING PROTEIN; HYBRID PROTEIN; ISOPROTEIN; MYC PROTEIN; PROTEIN MM1ALPHA; PROTEIN MM1BETA; PROTEIN MM1DELTA; PROTEIN MM1GAMMA; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CELL NUCLEUS; CHROMOSOME 12; CHROMOSOME 14; CONTROLLED STUDY; CYTOPLASM; E BOX ELEMENT; HELA CELL; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN ISOLATION; PROTEIN LOCALIZATION; REPORTER GENE; TRANSCRIPTION REGULATION;

BASE SEQUENCE; CELL LINE; DNA PRIMERS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN ISOFORMS; PROTO-ONCOGENE PROTEINS C-MYC; REPRESSOR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA SPLICING;

EID: 30044449708     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.20619     Document Type: Article

References (16)

1. Chen SJ, Zelent A, Tong JH, Yu HO, Wang ZY, Derre J, Berger R, Waxman S, Chen Z. 1993a. Rearrangements of the retinoic acid receptor alpha and promyelocytic leukemia zinc finger genes resulting from t(11;17)(q23;q21) in a patient with acute promyelocytic leukemia. J Clin Invest 91:2260-2267.
2. Chen Z, Brand NJ, Chen A, Chen SJ, Tong JH, Wang ZY, Waxman S, Zelent A. 1993. Fusion between a novel Kruppel-like zinc finger gene and the retinoic acid receptor-alpha locus due to a variant t(11;17) translocation associated with acute promyelocytic leukaemia. EMBO J 12:1161-1167.
3. Chen Z, Guidez F, Rousselot P, Agadir A, Chen SJ, Wang ZY, Degos L, Zelent A, Waxman S, Chomienne C. 1994. PLZF-RAR alpha fusion proteins generated from the variant t(11;17)(q23;q21) translocation in acute promyelocytic leukemia inhibit ligand-dependent transactivation of wild-type retinoic acid receptors. Proc Natl Acad Sci USA 91:1178-1182.
4. Dang CV. 1999. c-Myc target genes involved in cell growth, apoptosis, and metabolism. Mol Cell Biol 19:1-11.
5. de The H, Lavau C, Marchio A, Chomienne C, Degos L, Dejean A. 1991. The PMLRAR alpha fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR. Cell 66:675-684.
6. Fujioka Y, Taira T, Maeda Y, Tanaka S, Nishihara H, Iguchi-Ariga SMM, Nagashima K, Ariga H. 2001. MM-1, a c-Myc-binding protein, is a candidate for a tumor suppressor in leukemia/lymphoma and tongue cancer. J Biol Chem 276:45137-45144.
7. Geissler S, Siegers K, Schiebel E. 1998. A novel protein complex promoting formation of functional alpha- and gamma-tubulin. EMBO J 145:265-277.
8. Graham FL, Vander EB AJ. 1973. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology 52:456-467.
9. Kakizuka A, Miller WH, Jr., Umesono K, Warrell RP, Jr., Frankel SR, Murty W, Dmitrovsky E, Evans RM. 1991. Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RAR alpha with a novel putative transcription factor, PML. Cell 66:663-674.
10. Mori K, Maeda Y, Kitaura H, Taira T, Iguchi-Ariga SMM, Ariga H. 1998. MM-1, a novel C-MYC associating protein which represses transcriptional activity of C-MYC. J Biol Chem 273:29794-29800.
11. Obaya AJ, Mateyak MK, Sedivy JM. 1999. Mysterious liaisons: The relationship between c-Myc and the cell cycle. Oncogene 18:2934-2941.
12. Prendergast GC. 1999. Mechanisms of apoptosis by c-Myc. Oncogene 18:2967-2987.
13. Satou A, Taira T, Iguchi-Ariga SMM, Ariga H. 2001. A novel transrepression pathway of c-Myc-Recruitment of a transcriptional corepressor complex to c-Myc by MM-1, a c-Myc-binding protein. J Biol Chem 276:46562-46567.
14. Satou A, Hagio Y, Taira T, Iguchi-Ariga SMM, Ariga H. 2004. Repression of the cfms gene in fibroblast cells by c-Myc-MM-1-TIF1β complex. FEBS Lett 572:211-215.
15. Vainberg IE, Lewis SA, Rommelaere H, Ampe C, Vandekerckhove J, Klein HL, Cowan NJ. 1998. Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin. Cell 93:863-873.
16. Watanabe K, Ozaki T, Nakagawa T, Miyazaki K, Takahashi M, Hosoda M, Hayashi S, Todo S, Nakagawara A. 2002. Physical interaction of p73 with c-Myc and MM1, a c-Myc-binding protein, and modulation of the p73 function. J Biol Chem 277:15113-15123.