Determination of exemestane and its related compounds in tablets by RP-HPLC

Journal of China Pharmaceutical University

Volumn 33, Issue 6, 2002, Pages 537-539

  Li, Wei Lan ^a   Zheng, Xiang Yu ^a  

^a SOUTHEAST UNIVERSITY   (China)

Author keywords

Determination of content; Exemestane; Related compound; RP HPLC

Indexed keywords

ACETONITRILE; EXEMESTANE; METHANOL; POTASSIUM DIHYDROGEN PHOSPHATE;

ARTICLE; DRUG DETERMINATION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TABLET;

EID: 30044449154     PISSN: 10005048     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (4)

1. Kaufmann M,Bejetta E,Dirix LY,et al. Survival advantage of exemestane (EXE. Aromasin (r)) over megestrol acetate in postmenopausal women with advanced breast cancer refractory to tamoxifen: result of a phase III randomized doubleblind study [abstract no. 412][J]. Proc Am Soc Clin Oncol, 1999, 18: 109-110.
2. Breda M,Pianezzola E,Strolin Benedetti M,et al. Determination of exemestane, a new aromatase inhibitor in plasma by high-performance liquid chromatography with ultraviolet detection [J]. J Chromatogr Biomed Appl, 1993,620(2):225-231.
3. Persiani S,Broutin F,Cicioni P, et al. Determination of the new aromatase inhibitor exemestane in biological fluids by automated high-performance liquid chromatography followed by radioimmunoassay[J] Eur J Pharm Sci,1996,4(6):331- 340.
4. Allievi C,Zugnoni P,Benedetti MS,et al. Determination of plasma levels of exemestane(FCE 24304), a new irreversible aromatase inhibitor using liquid chromatography/thermospray massspectrometry[J]. J Mass Spectrom, 1995,30(5):693-697.