Cloxacillin versus vancomycin for presumed late-onset sepsis in the Neonatal Intensive Care Unit and the impact upon outcome of coagulase negative staphylococcal bacteremia: A retrospective cohort study

BMC Pediatrics

Volumn 5, Issue , 2005, Pages

  Lawrence, Sarah L ^a   Roth, Virginia ^a   Slinger, Robert ^b   Toye, Baldwin ^a   Gaboury, Isabelle ^b   Lemyre, Brigitte ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

^b CHILDREN S HOSPITAL OF EASTERN ONTARIO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CLOXACILLIN; GENTAMICIN; VANCOMYCIN; ANTIINFECTIVE AGENT; COAGULASE;

ARTICLE; BACTEREMIA; BLOOD CULTURE; COAGULASE NEGATIVE STAPHYLOCOCCUS; COHORT ANALYSIS; CONFIDENCE INTERVAL; CONTROLLED STUDY; DISEASE DURATION; DRUG USE; HUMAN; MAJOR CLINICAL STUDY; NEWBORN; NEWBORN INTENSIVE CARE; NEWBORN MORTALITY; NEWBORN SEPSIS; OUTCOMES RESEARCH; RETROSPECTIVE STUDY; ANTIBIOTIC RESISTANCE; COMPARATIVE STUDY; MORTALITY; OUTCOME ASSESSMENT; PATHOPHYSIOLOGY; PROPORTIONAL HAZARDS MODEL; STAPHYLOCOCCUS INFECTION;

ANTI-BACTERIAL AGENTS; BACTEREMIA; CLOXACILLIN; COAGULASE; COHORT STUDIES; GENTAMICINS; HUMANS; INFANT, NEWBORN; INTENSIVE CARE UNITS, NEONATAL; OUTCOME ASSESSMENT (HEALTH CARE); PROPORTIONAL HAZARDS MODELS; RETROSPECTIVE STUDIES; STAPHYLOCOCCAL INFECTIONS; VANCOMYCIN; VANCOMYCIN RESISTANCE;

EID: 30044439875     PISSN: 14712431     EISSN: 14712431     Source Type: Journal    
DOI: 10.1186/1471-2431-5-49     Document Type: Article

References (24)

1. Karlowicz MG, Buescher ES, Surka AE: Fulminant late-onset sepsis in a neonatal intensive care unit, 1988-1997, and the impact of avoiding empiric vancomycin therapy. Pediatrics 2000, 106(6):1387-1390
2. Bonten MJ, Willems R, Weinstein RA: Vancomycin-resistant enterococci: why are they here, and where do they come from? Lancet Infect Dis 2001, 1(5):314-25
3. Martone WJ: Spread of Vancomycin-resistant, entercocci: why did it happen in the United States? Infect Control Hosp Epidemiol 1998, 19(8):539-45
4. Garrett DO, Jochimsen E, Murfitt K, Hill B, McAllister S, Nelson P, Spera RV, Sall RK, Tenover FC, Johnston J, Zimmer B, Jarvis WR: The emergence of decreased susceptibility to vancomycin in Staphylococcus Epidermidis. Infect Control Hosp Epidemiol 1999, 20(3):167-70
5. Veach LA, Pfaller MA, Barrett M, Koontz FP, Wenzel RP: Vancomycin resistance in Staphylococcus Haemolyticus causing colonization and bloodstream infection. J Clin Microbiol 1990, 28(9):2064-8
6. Public health dispatch: vancomycin-resistant Staphylococcus Aureus: Morbidity and mortality weekly report 2002, 51(40):902-4
7. Staphylococcus Aureus resistant to vancomycin: Morbidity and mortality weekly report 2002, 51(26):565-7
8. Interim guidelines for prevention and control of staphylococcal infection associated with reduced susceptibility to vancomycin: Morbidity and mortality weekly report 1997; 46(27):626
9. Hospital Infection Control Practices Advisory Committee: Recommendations for preventing the spread of vancomycin resistance. Infect Control Hosp Epidemiol 1995, 16:105-113
10. Matrai-Kovalskis Y, Greenberg D, Shinwell ES, Fraser D, Dagan R: Positive blood cultures for coagulase-negative staphylococci in neonates: does highly selective vancomycin usage affect outcome? Infection 1998, 26(2):85-92
11. Krediet TG, Jones ME, Gerards LJ, Fleer A: Clinical outcome of cephalothin versus vancomycin therapy in the treatment of coagulase-negative staphylococcal septicemia in neonates: relation to methicillin resistance and mec A gene carriage of blood isolates. Pediatrics 1999, 103(3):e29
12. Lam JPH, Mitchell SJ, Gore C: Selective use of vancomycin for empirical treatment of neonatal sepsis: effects on clinical outcome and glycopeptide usage. Arch Dis Child 2001, 84 suppl 1:A63
13. Allen TR, da Silva OP: Choice of antibiotics in late neonatal sepsis in the extremely low birth weight infant. Can J Infect Dis Med Microbiol 2003, 14(1):28-31
14. Furigay PJ, Karlowicz MG, Croitoru IDP, Buescher ES: Coagulase-negative staphylococcal bacteremia in neonates: Can it be treated successfully with vancomycin without removing central venous catheters? Pediatr Res 2000, 47(4):340A
15. Karlowicz MG, Furigay PJ, Croitoru DP, Buescher ES: Central venous catheter removal versus in situ treatment in neonates with coagulase-negative staphylococcal bacteremia. Pediatr Infect Dis J 2002, 21(1):22-7
16. Benjamin DK Jr, Miller W, Garges H, Benjamin DK, McKinney RE Jr, Cotton M, Fisher RG, Alexander KAI: Bacteremia, central catheters, and neonates: when to pull the line. Pediatrics 2001, 107(6):1272-6
17. Woods W, Ramotar K, Lem P, Toye B: Oxacillin susceptibility testing of coagulase-negative staphylococci using the disk diffusion method and the Vitek GPS-105 card. Diag Microbiol Infect Dis 2002, 42:291-294
18. Jones B, Jarvis P, Lewis JA, Ebbutt AF: Trials to assess equivalence: the importance of rigorous methods. BMJ 1996, 313:36-39
19. Newcombe RG: Interval estimation for the difference between independent proportions: comparison of eleven methods. Stat Med 1998, 17(8):873-890
20. Watanakunakorn C, Glotzbecker C: Enhancement of the effects of anti-Staphylococcal antibiotics by aminoglycosides. Antimicrob Agents Chemother 1974, 6:802-806.
21. Struthers S, Underhill H, Albersheim S, Greenberg D, Dobson S: A comparison of two versus one blood culture in the diagnosis and treatment of coagulase-negative staphylococcus in the Neonatal intensive care unit. J Perinatol 2002, 22:547-9
22. Sarkar S, Bhagat I, Mele P, Herbert C, Wiswell TE, Spitzer AR: A prospective trial of multiple site blood cultures in the initial evaluation of neonatal sepsis [abstract]. Pediatr Res 2003, 53 (4 part 2):442A
23. Donlan RM: Biofilms and Device-Associated Infections. Emerging infectious disease. 2001:7(2)
24. Rubin LG, Sanchez PJ, Siegel J, Levine G, Saiman L, Jarvis WR: Evaluation and treatment of neonates with suspected late-onset sepsis: a survey of neonatologists' practices. Pediatrics 2002, 110(4):e42